TESTICULAR TISSUE TRANSPLANTATION OR TESTOSTERONE ADMINISTRATION IN BILATERALLY CASTRATED MALE RATS: EFFECTS ON MATING TEST AND MOLECULAR PARAMETERS OF ERECTILE FUNCTION

2008 ◽  
Vol 7 (3) ◽  
pp. 296
Author(s):  
N. Pardalidis ◽  
D. Giannakis ◽  
D. Baltogiannis ◽  
P. Tsounapi ◽  
N. Giotitsas ◽  
...  
Keyword(s):  
Erectile Function ◽  
Testicular Tissue ◽  
Tissue Transplantation ◽  
Male Rats ◽  
Mating Test ◽  
Molecular Parameters ◽  
Testosterone Administration

Effects of Chronic Hyperprolactinemia on Sexual Arousal and Erectile Function in Male Rats

1986 ◽  
Vol 42 (5) ◽  
pp. 368-375 ◽  
Author(s):  
Paul C. Doherty ◽  
Michael J. Baum ◽  
Roberta B. Todd
Keyword(s):  
Sexual Arousal ◽  
Erectile Function ◽  
Male Rats

Losartan Preserves Erectile Function After Bilateral Cavernous Nerve Injury via Antifibrotic Mechanisms in Male Rats

2009 ◽  
Vol 181 (6) ◽  
pp. 2816-2822 ◽  
Author(s):  
Onder Canguven ◽  
Gwen Lagoda ◽  
Sena F. Sezen ◽  
Arthur L. Burnett
Keyword(s):  
Nerve Injury ◽  
Erectile Function ◽  
Male Rats ◽  
Cavernous Nerve ◽  
Cavernous Nerve Injury

Testicular Tissue Transplantation for Fertility Preservation

2012 ◽  
pp. 141-157
Author(s):  
Jose R. Rodriguez-Sosa ◽  
Stefan Schlatt ◽  
Ina Dobrinski
Keyword(s):  
Fertility Preservation ◽  
Testicular Tissue ◽  
Tissue Transplantation

scholarly journals Curcumin Along With Fe3O4 Nanoparticles Improved Sperm Parameters In Rats With Testicular Ischemia

2021 ◽  
Vol 10 ◽  
pp. e2034
Author(s):  
Shabnam Zarei Moradi ◽  
Seyed Abdolhamid Angaji ◽  
Mitra Salehi ◽  
Mehrdad Hashemi
Keyword(s):  
Fe3o4 Nanoparticles ◽  
Sperm Concentration ◽  
Concomitant Administration ◽  
Testicular Tissue ◽  
Sperm Parameters ◽  
Male Rats ◽  
Semen Parameters ◽  
Control Group ◽  
Fe3o4 Nps ◽  
Testicular Ischemia

Background: Ischemic/reperfusion (I/R) in testicular tissue is one reason for the worldwide increase in male infertility. In the present study, we assessed the effects of curcumin and Fe3O4 nanoparticles (NPs) on sperm parameters in rats with I/R damage. Materials and Methods: Forty-eight adult male rats were divided into two groups (n=24 per group): control and torsion/detorsion. The control and torsion/detorsion groups were divided into four subgroups include sham, Fe3O4 NPs, curcumin, and Fe3O4 NPs+curcumin. After the rats were sacrificed, semen was collected from their epididymal tissues to assess sperm viability, motility, concentration, and morphology. Results: Curcumin significantly improved viability, motility, and normal sperm morphology in rats with I/R damage compared to the control group; however, it did not have a significant effect on sperm concentration (P<0.001). Fe3O4 NPs alone decreased all sperm parameters in the control and I/R rats (P<0.001). However, concomitant administration of Fe3O4 nanoparticles with curcumin significantly improved sperm parameters in rats with I/R damage (P<0.001). Conclusion: The increase in all semen parameters in the experimental groups with concomitant use of Fe3O4 NPs plus curcumin indicated that green synthesis of NPs could be recommended for future clinical studies.

scholarly journals The effect of testosterone on the rate of oxygen consumption by prostate tissue

2018 ◽  
Vol 99 (5) ◽  
pp. 775-778
Author(s):  
A O Lobkarev ◽  
R Kh Khafiz’yanova ◽  
O A Lobkarev
Keyword(s):  
Oxygen Consumption ◽  
Chronic Prostatitis ◽  
Clinical Effectiveness ◽  
Prostatic Hyperplasia ◽  
Prostate Tissue ◽  
Male Rats ◽  
Rate Of Oxygen Consumption ◽  
Testosterone Administration ◽  
Air Tightness ◽  
Increasing Demand

Aim. To study the effect of testosterone on the rate of oxygen consumption by rodent prostate homogenate. Methods. The study included 30 healthy old white outbred male rats divided into two groups with 15 animals in each group. The rats of the first group were administered the application of 1 % testosterone-containing gel Androgel before the operation. The rats of the second group received no testosterone. Under anesthesia prostatectomy was performed. Homogenate was immediately prepared from each prostate. Further every homogenate was placed into 250 ml vial to determine the rate of oxygen consumption. Then the device measuring the concentration of oxygen dissolved in water was placed into the vial, and the air-tightness was created. Each vial was put into the thermostat for 30 minutes at 36.6 ˚C. Then the measurement of the concentration of O2 dissolved in the water was performed. Results. Application of transdermal gel with 1 % testosterone was found to cause increase of oxygen consumption by prostate tissue. This fact can explain why the clinical effectiveness of testosterone is individual to each patient with benign prostatic hyperplasia (BPH) and chronic prostatitis (CP): oxygen supply to the prostate is different in each patient with BPH and CP. So not in every patient the oxygen-transporting system is capable of supplying prostate tissues with the amount of oxygen according to increasing demand of the organ on testosterone administration. Conclusion. Testosterone increases the rate of oxygen consumption by prostate tissue.

THE EFFECT OF STILBOESTROL ANALOGUES ON THE METABOLISM OF STEROIDS BY THE TESTIS AND PROSTATE OF THE RAT IN VITRO

1973 ◽  
Vol 59 (3) ◽  
pp. 539-544 ◽  
Author(s):  
VARAPAN DANUTRA ◽  
MAUREEN E. HARPER ◽  
K. GRIFFITHS
Keyword(s):  
Marked Effect ◽  
Enzyme System ◽  
Testicular Tissue ◽  
Sesame Oil ◽  
Prostatic Tissue ◽  
Synthetic Activity ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Testosterone Administration

SUMMARY Male Sprague—Dawley rats were injected (i.m.) daily for 10 days with 100 μg of either oestradiol-17β, diethylstilboestrol (DES), dl-dihydrodibutylstilboestrol (dl-DHBS) or meso-dihydrodibutylstilboestrol (meso-DHBS) in 0·2 ml sesame oil. After 10 days, the testicular tissue was removed and incubated simultaneously with [7α-3H]dehydroepiandrosterone and [4-14C]17α-hydroxyprogesterone. Less testosterone was synthesized by the testicular tissue from animals treated with oestradiol-17β, DES and meso-DHBS than by the controls or animals treated with dl-DHBS. The decreased synthetic activity was related to the decreased activity of both the 17β-hydroxysteroid dehydrogenase and 17α-pregnene-C17, 20-lyase enzyme systems. Prostatic tissue was also incubated with [7α-3H]testosterone. Administration of DES, oestradiol-17β or meso-DHBS increased the metabolism of testosterone by the prostatic tissue with a marked effect on the 5α-reductase enzyme system.

THE EFFECT OF CERTAIN ANDROGENIC STEROIDS ON THE UPTAKE OF RADIOSULPHUR IN A HEALING FRACTURED BONE IN THE RAT

1957 ◽  
Vol 35 (1) ◽  
pp. 771-776 ◽  
Author(s):  
K. Kowalewski ◽  
R. T. Morrison
Keyword(s):  
Normal Control ◽  
Marked Effect ◽  
Testosterone Propionate ◽  
Chondroitin Sulphate ◽  
Significant Rise ◽  
Male Rats ◽  
Testosterone Administration ◽  
Androgenic Steroids ◽  
Intact Rats

The uptake of radiosulphur in the fractured and intact humerus of male rats was determined in normal and in castrated animals and the ratio F/I of radioactivity of fractured (F) to intact (I) bone was calculated. Castration resulted in a significant decrease of F/I ratio, as compared with normal control rats.The effect of testosterone propionate and 17-ethyl-19 nortestosterone (Nilevar) on the S35 uptake in bones was studied. Testosterone administration resulted in a slight increase of the F/I in castrated rats, but had no effect on this ratio in intact animals. Both castrated and intact rats treated with Nilevar exhibited a significant rise of S35 uptake in fractured bones and, consequently, high F/I ratios. It is suggested that Nilevar has a marked effect on the synthesis of chondroitin sulphate in the collagen tissues of healing fractures, as measured by the described S35 uptake technique.

THE EFFECT OF CERTAIN ANDROGENIC STEROIDS ON THE UPTAKE OF RADIOSULPHUR IN A HEALING FRACTURED BONE IN THE RAT

1957 ◽  
Vol 35 (10) ◽  
pp. 771-776 ◽  
Author(s):  
K. Kowalewski ◽  
R. T. Morrison
Keyword(s):  
Normal Control ◽  
Marked Effect ◽  
Testosterone Propionate ◽  
Chondroitin Sulphate ◽  
Significant Rise ◽  
Male Rats ◽  
Testosterone Administration ◽  
Androgenic Steroids ◽  
Intact Rats

The uptake of radiosulphur in the fractured and intact humerus of male rats was determined in normal and in castrated animals and the ratio F/I of radioactivity of fractured (F) to intact (I) bone was calculated. Castration resulted in a significant decrease of F/I ratio, as compared with normal control rats.The effect of testosterone propionate and 17-ethyl-19 nortestosterone (Nilevar) on the S35 uptake in bones was studied. Testosterone administration resulted in a slight increase of the F/I in castrated rats, but had no effect on this ratio in intact animals. Both castrated and intact rats treated with Nilevar exhibited a significant rise of S35 uptake in fractured bones and, consequently, high F/I ratios. It is suggested that Nilevar has a marked effect on the synthesis of chondroitin sulphate in the collagen tissues of healing fractures, as measured by the described S35 uptake technique.

Erectile function in male rats after lesions in the lateral paragigantocellular nucleus

1999 ◽  
Vol 262 (3) ◽  
pp. 203-206 ◽  
Author(s):  
Yian-Cheng Liu ◽  
Benjamin D Sachs
Keyword(s):  
Erectile Function ◽  
Male Rats
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