314 MiR200c as outcome predictor of renal cell cancer patients with tumor thrombus of the inferior vena cava (IVC)

2012 ◽  
Vol 11 (1) ◽  
pp. e314
Author(s):  
D.C. Vergho ◽  
C. Kalogirou ◽  
M. Spahn ◽  
A. Loeser ◽  
A. Rosenwald ◽  
...  
Keyword(s):  
Inferior Vena Cava ◽  
Cancer Patients ◽  
Renal Cell Cancer ◽  
Renal Cell ◽  
Tumor Thrombus ◽  
Inferior Vena ◽  
Cell Cancer ◽  
Vena Cava ◽  
Outcome Predictor

scholarly journals Multidisciplinary surgical treatment of clear-cell renal carcinoma with inferior vena cava tumor thrombus level III and IV: our experience during the past decade

2020 ◽  
Vol 48 (2-3) ◽  
pp. 68-72
Author(s):  
Tvrtko Hudolin ◽  
◽  
Vladimir Ferenčak ◽  
Luka Penezić ◽  
Toni Zekulić ◽  
...  
Keyword(s):  
Inferior Vena Cava ◽  
Renal Cell ◽  
Tumor Thrombus ◽  
Inferior Vena ◽  
Clear Cell ◽  
Cell Cancer ◽  
Vena Cava ◽  
Cell Renal Cell Carcinoma ◽  
Cell Renal Carcinoma ◽  
Primary Determinant

Patients with non-metastatic, stage T3 clear-cell renal cell cancer present a clinical challenge for urologists. The extent of tumor thrombus in inferior vena cava is the primary determinant of surgical procedure complexity. Level III and IV thrombi require the use of cardiopulmonary bypass and hypothermic arrest. Careful preoperative planning and a multidisciplinary approach are mandatory. In this paper, we report outcomes of 12 patients who were surgically treated in our center. The 29 months overall survival for all patients was 69%, while three patients died during follow-up. Of nine surviving patients, six are currently disease-free, whereas three had disease progression. Our study showed that carefully selected patients with clear-cell renal cell carcinoma with inferior vena cava tumor thrombus level III and IV could be successfully treated with an aggressive surgical approach.

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