974 Impact of preoperative proteinuria on postoperative renal functional outcome after open partial nephrectomy: A propensity score matching study

2016 ◽  
Vol 15 (3) ◽  
pp. e974
Author(s):  
H. Tachibana ◽  
T. Takagi ◽  
J. Iizuka ◽  
T. Kondo ◽  
K. Tanabe
Keyword(s):  
Propensity Score ◽  
Functional Outcome ◽  
Propensity Score Matching ◽  
Partial Nephrectomy ◽  
Open Partial Nephrectomy

scholarly journals Severity assessment in maximally treated ICH patients

Neurology ◽  
2017 ◽  
Vol 89 (5) ◽  
pp. 423-431 ◽  
Author(s):  
Jochen A. Sembill ◽  
Stefan T. Gerner ◽  
Bastian Volbers ◽  
Tobias Bobinger ◽  
Hannes Lücking ◽  
...  
Keyword(s):  
Propensity Score ◽  
Functional Outcome ◽  
Propensity Score Matching ◽  
Scale Score ◽  
Predictive Validity ◽  
Assessment Tool ◽  
Favorable Outcome ◽  
Severity Assessment ◽  
Poor Outcome ◽  
Ich Score

Objective:As common prognostication models in intracerebral hemorrhage (ICH) are developed variably including patients with early (<24 hours) care limitations (ECL), we investigated its interaction with prognostication in maximally treated patients and sought to provide a new unbiased severity assessment tool.Methods:This observational cohort study analyzed consecutive ICH patients (n = 583) from a prospective registry over 5 years. We characterized the influence of ECL on overall outcome by propensity score matching and on conventional prognostication using receiver operating characteristic analyses. We established the max-ICH score based on independent predictors of 12-month functional outcome in maximally treated patients and compared it to existing models.Results:Prevalence of ECL was 19.2% (n = 112/583) and all of these patients died. Yet propensity score matching displayed that 50.7% (n = 35/69) theoretically could have survived, with 18.8% (n = 13/69) possibly reaching favorable outcome (modified Rankin Scale score 0–3). Conventional prognostication seemed to be confounded by ECL, documented by a decreased predictive validity (area under the curve [AUC] 0.67, confidence interval [CI] 0.61–0.73 vs AUC 0.80, CI 0.76–0.83; p < 0.01), overestimating poor outcome (mortality by 44.8%, unfavorable outcome by 10.1%) in maximally treated patients. In these patients, the novel max-ICH score (0–10) integrates strength-adjusted predictors, i.e., NIH Stroke Scale score, age, intraventricular hemorrhage, anticoagulation, and ICH volume (lobar and nonlobar), demonstrating improved predictive accuracy for functional outcome (12 months: AUC 0.81, CI 0.77–0.85; p < 0.01). The max-ICH score may more accurately delineate potentials of aggressive care, showing favorable outcome in 45.4% (n = 214/471) and a long-term mortality rate of only 30.1% (n = 142/471).Conclusions:Care limitations significantly influenced the validity of common prognostication models resulting in overestimation of poor outcome. The max-ICH score demonstrated increased predictive validity with minimized confounding by care limitations, making it a useful tool for severity assessment in ICH patients.

517 COMPARISON OF RENAL FUNCTIONAL OUTCOME AFTER LAPAROSCOPIC AND OPEN PARTIAL NEPHRECTOMY

2010 ◽  
Vol 183 (4S) ◽  
Author(s):  
Yasuhito Funahashi ◽  
Ryohei Hattori ◽  
Tokunori Yamamoto ◽  
Momokazu Gotoh
Keyword(s):  
Functional Outcome ◽  
Partial Nephrectomy ◽  
Open Partial Nephrectomy

1435 IMPACT OF ISCHEMIA TIME AND MODALITY ON RENAL FUNCTIONAL OUTCOME AFTER OPEN PARTIAL NEPHRECTOMY

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Seth A. Cohen ◽  
Kerrin L. Palazzi ◽  
Sean P. Stroup ◽  
James H. Masterson ◽  
Ryan P. Kopp ◽  
...  
Keyword(s):  
Functional Outcome ◽  
Partial Nephrectomy ◽  
Open Partial Nephrectomy ◽  
Ischemia Time

scholarly journals Comparison of Sutureless and Conventional Laparoscopic Partial Nephrectomy: A Propensity Score-Matching Analysis

2021 ◽  
Vol 11 ◽  
Author(s):  
Feng Zhang ◽  
Shuang Gao ◽  
Yiqiao Zhao ◽  
Bin Wu ◽  
Xiaonan Chen
Keyword(s):  
Propensity Score ◽  
Propensity Score Matching ◽  
Partial Nephrectomy ◽  
Laparoscopic Partial Nephrectomy ◽  
Renal Tumors ◽  
Tumor Diameter ◽  
Propensity Score Matching Analysis ◽  
Conventional Laparoscopic ◽  
Before And After ◽  
T1 Stage

Objective: To compare the functional outcome, safety and efficacy of sutureless and conventional laparoscopic partial nephrectomy.Methods: After the inclusion and exclusion criteria were applied, our study reviewed 379 patients with T1 stage renal tumors. We applied propensity score matching (PSM) to limit potential baseline confusion. Perioperative and functional outcomes between sutureless laparoscopic partial nephrectomy (sLPN) and conventional laparoscopic partial nephrectomy (cLPN) groups were compared and analyzed before and after PSM.Results: Of our 379 patients with T1 stage renal tumors, 199 and 180 were identified in the cLPN and sLPN groups, respectively. After applying PSM with preoperative features, 116 patients in the cLNP group were paired to 116 patients in the sLNP group. We found that all differences in preoperative baseline characteristics disappeared. All the preoperative characteristics (age, gender, tumor diameter, RENAL nephrometry score, side, preoperative eGFR, hypertension, diabetes mellitus, ASA score) were not statistically different between the two groups. The operative time (OT) (p &lt; 0.001) and warm ischemia time (WIT) (p &lt; 0.001) of the sLPN group were of shorter duration than that of the cLPN group. The eGFR baseline was almost equal, but there was a statistically smaller decrease in eGFR in the sLPN than in the cLPN group 1 week after surgery (14.3 vs. 7.4, p &lt; 0.001) and after 6 months (11.9 vs. 5.0, p &lt; 0.001). After both preoperative features and WIT were included in PSM, fifty-one pairs of patients were identified between the groups, the WIT difference between them disappeared, while the decrease in eGFR between the groups remained as it was previously at 1 week (15.4 vs. 8.6, p &lt; 0.001) and at 6 months (13.0 vs. 6.2, p &lt; 0.001).Conclusion: Sutureless laparoscopic partial nephrectomy is as safe and effective as conventional laparoscopic partial nephrectomy, and compared to cLPN, sLPN can effectively reduce the WIT, retain more renal parenchyma and protect renal function.

scholarly journals Comparison of perioperative outcomes with or without renorrhaphy during open partial nephrectomy: A propensity score-matched analysis

2018 ◽  
Vol 44 (3) ◽  
pp. 467-474 ◽  
Author(s):  
Hidekazu Tachibana ◽  
Toshio Takagi ◽  
Tsunenori Kondo ◽  
Hideki Ishida ◽  
Kazunari Tanabe
Keyword(s):  
Propensity Score ◽  
Partial Nephrectomy ◽  
Perioperative Outcomes ◽  
Open Partial Nephrectomy
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