Surgical treatment of renal cell carcinoma (RCC) with extended inferior vena cava (IVC) thrombosis: Oncological outcomes

2019 ◽  
Vol 18 (11) ◽  
pp. e3530
Author(s):  
V. Atduev ◽  
D. Ledyaev ◽  
Y. Lyubarskaya ◽  
Z. Amoev ◽  
A. Danilov ◽  
...  
2018 ◽  
Vol 0 (3) ◽  
pp. 75-79
Author(s):  
I. I. Kobza ◽  
Yu. S. Mota ◽  
S. A. Lebedeva ◽  
Yu. G. Orel ◽  
R. A. Zhuk

2020 ◽  
Vol 99 (4) ◽  
pp. 167-171

Introduction: Thrombosis of inferior vena cava (IVC) is an important complication amongst oncological patients. Tumor thrombus of IVC is characteristic for patients with renal cell carcinoma, occurring in 10−18%. The aim of the work is to analyze of surgical treatment in patients with cancer thrombosis of inferior vena cava in kidney cancer. Methods: Between 2010 and 2019 we treated 32 patients with kidney cancer complicated by thrombotic infiltration of the inferior vena cava. According to Nesbitt classification the levels of thrombotic infiltration of the inferior vena cava were: I–8 (25%), II–14 (43.8%), III–6 (18.8%), and IV–4 (12.5%). Nephrectomy with thrombectomy of the cancer thrombus in the inferior vena cava was performed in all patients. In addition to laparotomy, sternotomy was approached in 4 patients with Nesbitt IV and in 2 patients with Nesbitt III. Results: Primary suture of IVC was performed in 26 patients; angioplasty of IVC was performed in 4 patients; and resection of IVC with replacement using a polytetrafluoroethylene interposition graft was done in 2 patients. Radical surgical treatment was performed in 27 (84.3%) patients, and palliative in 5 (15.6%) patients. In the postoperative period, 1 (3.1%) patient (Nesbitt IV) died of cardiac failure during hospitalisation. Two-year survival was observed in 75% of the cases. Conclusion: Tumorous infiltration of IVC is associated with a high potential for tumour embolisation to the lungs, leading to the formation of multiple metastases and spreading of the underlying disease. Postoperative comfort is improved considerably after nephrectomy of the affected kidney and removal of the tumour thrombus, including IVC resection as appropriate, and when combined with oncological treatment, the survival rate is increased significantly, as well.


2008 ◽  
Vol 31 (2) ◽  
pp. 75-82 ◽  
Author(s):  
Tawatchai Taweemonkongsap ◽  
Chaiyong Nualyong ◽  
Sunai Leewansangtong ◽  
Teerapon Amornvesukit ◽  
Yongyut Sirivatanauksorn ◽  
...  

2020 ◽  
Vol 7 (3) ◽  
pp. 91-98
Author(s):  
N. V. Vorobev ◽  
F. S. Ashyrova ◽  
M. P. Golovashchenko ◽  
L. O. Petrov ◽  
A. D. Kaprin

Among malignant neoplasms, kidney cancer occupies one of the first places in terms of the growth rate of incidence in Russia. Despite the possibilities of modern diagnostic research methods, the number of patients with common forms of the disease does not decrease. In 5–10% of cases, renal cell carcinoma is complicated by the formation of a tumor clot in the inferior Vena cava (VCI), which requires volume surgery — nephrectomy with thrombectomy, which is the only effective treatment option for this group of patients. Previously, the results of treatment of locally advanced kidney cancer were unsatisfactory due to the high incidence of complications and mortality after extended surgical interventions. However, improving the operation technique requires a re-evaluation of previous representations. Performing a nephrectomy with a VCI thrombectomy is not an easy task and is often associated not only with technical difficulties due to the need for mobilization, control and resection of the inferior Vena cava, but also with the risk of intra — and postoperative complications. The most difficult task is the choice of surgical tactics for descending non-tumor hemorrhagic thrombosis. As a result of long-term tumor obstruction, organized blood clots that are soldered to the intima of the vessel often spread to the common iliac veins and, as a rule, are technically impossible to remove. If the VCI is preserved, a residual hemorrhagic blood clot in the area of its confluence is a potential source of pulmonary embolism (PE), for the prevention of which mechanical plication is used. This maneuver does not lead to the development of clinically significant chronic venous insufficiency of the lower extremities (CVI NC), postoperative VCI or PE thrombosis. Despite the technical complexity of the operation and the difficult course of the postoperative period, surgical treatment of renal cell cancer complicated by tumor thrombosis is certainly justified. This article presents a clinical case of surgical treatment of a patient with renal cell cancer complicated by massive specific (tumor) and non-specific thrombosis in the presence of reduced parenchymalexcretory function of the contralateral kidney and severe cardiac pathology. Goal: to share experience and demonstrate the results of successful surgical treatment of renal cell carcinoma.


2017 ◽  
Vol 13 (1) ◽  
pp. 27-36 ◽  
Author(s):  
M. I. Davydov ◽  
V. B. Matveev ◽  
M. I. Volkova ◽  
A. K. Begaliev ◽  
P. I. Feoktistov ◽  
...  

1997 ◽  
Vol 2 (4) ◽  
pp. 213-218
Author(s):  
Kazuo Gohji ◽  
Koichi Ueno ◽  
Akinobu Gotoh ◽  
Isao Hara ◽  
Hiroshi Okada ◽  
...  

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