PP168-SUN BONE MINERAL DENSITY, BODY COMPOSITION AND TRAUMA MECHANISM IN YOUNG AND MIDDLE-AGED PATIENTS WITH FEMORAL NECK FRACTURE. A PROSPECTIVE MULTICENTRE STUDY ON 185 PATIENTS

2011 ◽  
Vol 6 (1) ◽  
pp. 87-88
Author(s):  
A. Al-Ani
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Femoral Neck ◽  
Multicentre Study ◽  
Femoral Neck Fracture ◽  
Trauma Mechanism ◽  
Mineral Density ◽  
Aged Patients ◽  
Prospective Multicentre Study ◽  
Neck Fracture

Low bone mineral density and fat-free mass in younger patients with a femoral neck fracture

2015 ◽  
Vol 45 (8) ◽  
pp. 800-806 ◽  
Author(s):  
Amer N. Al-Ani ◽  
Tommy Cederholm ◽  
Maria Sääf ◽  
Gustaf Neander ◽  
Richard Blomfeldt ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Femoral Neck ◽  
Femoral Neck Fracture ◽  
Bone Mineral ◽  
Fat Free Mass ◽  
Mineral Density ◽  
Younger Patients ◽  
Low Bone Mineral Density ◽  
Neck Fracture

scholarly journals Adipocytokine and ghrelin levels in relation to bone mineral density in physically active older women: longitudinal associations

2009 ◽  
Vol 160 (3) ◽  
pp. 381-385 ◽  
Author(s):  
Jaak Jürimäe ◽  
Tatjana Kums ◽  
Toivo Jürimäe
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Lumbar Spine ◽  
Femoral Neck ◽  
Older Women ◽  
Bone Mineral ◽  
Total Variance ◽  
Mineral Density ◽  
Physically Active ◽  
Independent Variables

PurposeWe investigated the relationship between the decrease in bone mineral mass (BMC) and bone mineral density (BMD) values with baseline adipocytokine and ghrelin concentrations in physically active postmenopausal women.MethodsLeptin, adiponectin, ghrelin, BMC, BMD and different body composition values were measured in 35 women (age: 69.7±6.0 years) before and after a 12-month prospective study period.ResultsSignificant (P<0.05) decreases in fat-free mass (FFM) (by 2.56%) and BMC (by 1.63%) and increases in adiponectin (by 14.8%) were seen in older females as a result of the study period. The independent variables that were associated with decreases in total BMC were baseline fat mass (FM) and adiponectin explaining 30.6% (R2×100) of the total variance. In another model, baseline FFM and leptin were the independent variables that explained 20.6% (P<0.05) of the total variance in the decreases in total BMD value. The variables that were associated with decreases in femoral neck BMD were FM and leptin (R2=0.102;P<0.05), while the independent variables were baseline trunk fat:leg fat ratio and adiponectin in the model with decreases in lumbar spine BMD as the dependent variable, and accounted for 13.1% (P<0.05) of the decreases in BMD variance.ConclusionsInitial adiponectin concentration together with specific body composition characteristics predicted loss in BMC and lumbar spine BMD values, while initial leptin concentration together with specific body composition parameters determined the loss in total and femoral neck BMD values in physically active older women.

scholarly journals POS0519 BONE MINERAL DENSITY, LEAN AND FAT MASS IN POSTMENOPAUSAL WOMEN WITH RHEUMATOID ARTHRITIS

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 493.2-493
Author(s):  
N. Toroptsova ◽  
O. Dobrovolskaya ◽  
A. Feklistov ◽  
O. Nikitinskaya ◽  
A. Efremova ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Femoral Neck ◽  
Postmenopausal Women ◽  
Bone Mineral ◽  
Fat Mass ◽  
Multivariate Linear Regression Analysis ◽  
Mineral Density ◽  
Total Hip ◽  
The Relationship

Background:The relationship between lean mass (LM), fat mass (FM) and bone mineral density (BMD) remains controversial. Some population studies have emphasized the positive association between them, while others have found an inverse relationship. RA patients are characterized by a decrease in muscle mass and an increase in fat mass. Such changes in body composition may be associated with low BMD.Objectives:To study the relationship between BMD, LM and FM in postmenopausal women with RA.Methods:68 postmenopausal women with RA (median age 59 [54; 63] years) were included in the study. BMD and body composition were evaluated using two-energy X-ray absorptiometry. Correlation analysis between body composition parameters and BMD was performed with the Spearman method, correlation coefficients R for p<0.05 are presented.Results:The average L1-L4 BMD was 0,92±0,16 g/cm2, total hip BMD - 0,84±0,15 g/cm2 and femoral neck - 0,73±0,13 g/cm2. 33 (48.5%) women had osteopenia, and 17 (25.0%) - osteoporosis (OP). Low appendicular LM was found in 5 (7.4%) and low appendicular muscle index (appendicular LM/height2, AMI) – in 10 (14.7%) patients. Overfat was revealed in 47 (69.1%) women, but only 20 (29.4%) women had BMI corresponding to obesity. The positive correlations between BMD in L1-L4, total hip and femoral neck regions and body weight (R=0.46, R=0.56 and R=0.50, respectively), trunk fat (R=0.4, R=0.51 and R=0.37, respectively), total FM (R=0.27, R=0.43 and R=0.34, respectively), trunk LM (R=0.55, R=0.54 and R=0.51, respectively), total LM (R=0.51, R=0.50 and R=0.52, respectively), appendicular LM (R=0.31, R=0.29 and R=0.37, respectively) and AMI (R=0.26, R=0.33 and R=0.51, respectively) were found out. In the multivariate linear regression analysis total LM was associated with BMD of lumbar spine (β=0.638, p=0.001) and total hip (β=0.473, p=0.008), and AMI - with femoral neck BMD (β=0.360; p=0.014). We found that FM hadn’t a significant effect on BMD in any region.Conclusion:73.5% of patients with RA had a reduced BMD, and 14.7% women – low AMI. LM was positively associated with BMDs in different regions of interest, but FM had no effect on BMD. Further researches are needed to identify associations between body composition, inflammatory activity and bone health in patients with RA.Disclosure of Interests:None declared

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