scholarly journals The Role of Magnetic Resonance Imaging in Acute Transverse Myelitis

Author(s):  
Sara G. Austin ◽  
Chi-Shing Zee ◽  
Cheryl Waters

ABSTRACT:Eighteen adult patients presenting with acute transverse myelitis (ATM) were evaluated using magnetic resonance imaging. Only 7 had abnormal scans showing an area of increased signal intensity within the cord solely on T2 weighted images; Tl weighted images were normal. The MRI abnormality did not correlate with the cause of the transverse myelitis, the extent of maximum neurological deficit, or the prognosis. A scan performed more than 5 days after the onset of disease was most likely to be positive. Even though the prognostic value of MRI in ATM may be limited, it remains a valuable technique for ruling out other causes of noncompressive spinal cord lesions, such as hemmorhage, vascular malformation, or tumor.

Author(s):  
Thomas Scott ◽  
Norbert Weikers ◽  
Mark Hospodar ◽  
Joseph Wapenski

Abstract:The prognostic value of magnetic resonance imaging (MRI) in the syndrome of acute transverse myelitis had not been evaluated. After retrospective study of 14 cases, we found that MRI is valuable for both diagnosis and prognosis in this illness. The criteria for the diagnosis of acute transverse myelitis consisted of acute onset (over less than 3 weeks) of symmetrical motor and sensory dysfunction referable to a distinct spinal cord level, with sphincter dysfunction. Patients with abnormal MRIs of the spinal cord had significantly worse outcomes than patients with normal MRIs.


Neurosurgery ◽  
2003 ◽  
Vol 52 (4) ◽  
pp. 806-816 ◽  
Author(s):  
Aaron A. Cohen-Gadol ◽  
Ofer M. Zikel ◽  
Gary M. Miller ◽  
Allen J. Aksamit ◽  
Bernd W. Scheithauer ◽  
...  

Abstract OBJECTIVE Neurosurgeons are frequently asked to evaluate patients for spinal cord biopsies when preoperative magnetic resonance imaging studies demonstrate nonspecific features. These lesions often appear unresectable, but surgeons must decide whether a biopsy is warranted. To determine the best approach to these cases, we evaluated the clinicopathological findings for patients with unknown spinal cord lesions who underwent spinal cord biopsies. METHODS Thirty-eight consecutive patients who underwent spinal cord biopsies at the Mayo Clinic (Rochester, MN) between August 1988 and July 1998 were studied. A detailed review of the case histories, radiological results, surgical notes, histological findings, and outcomes was performed. RESULTS Spinal cord biopsies were performed for 21 male and 17 female patients (mean age, 42.1 yr) with progressive neurological deficits related to spinal cord lesions. All patients underwent preoperative magnetic resonance imaging evaluations. High T2-weighted signal intensity and spinal cord expansion were identified in 92 and 87% of cases, respectively. After gadolinium infusion, the majority (94%) of the inflammatory lesions demonstrated patchy and often peripherally situated enhancement. This neuroradiological pattern was less common for neoplasms (50%) and benign lesions (40%). The most common pathological findings were inflammatory changes of demyelination or sarcoidosis, which together accounted for 13 cases (34%). Nonspecific changes or benign lesions were observed in 10 cases (26%). Neoplasms were identified in eight cases (21%). One case of tuberculosis and one of schistosomiasis were found. Overall, 47% of the preoperative diagnoses made by the attending surgeon were correct. For 26% of the patients, specific treatment was based on the biopsy results. The average follow-up period was 12 months (standard deviation, 14 mo; range, 0–50 mo). CONCLUSION Preoperative laboratory and imaging studies are often diagnostically inconclusive in cases of spinal cord lesions with nonspecific features. Biopsies should be considered for patients with progressive symptomatic lesions.


2011 ◽  
Vol 28 (8) ◽  
pp. 1401-1411 ◽  
Author(s):  
Anthony Bozzo ◽  
Judith Marcoux ◽  
Mohan Radhakrishna ◽  
Julie Pelletier ◽  
Benoit Goulet

2014 ◽  
Vol 14 (8) ◽  
pp. 1601-1610 ◽  
Author(s):  
Kenzo Uchida ◽  
Hideaki Nakajima ◽  
Naoto Takeura ◽  
Takafumi Yayama ◽  
Alexander Rodriguez Guerrero ◽  
...  

2019 ◽  
Vol 100 (4) ◽  
pp. 921-931 ◽  
Author(s):  
Kiran Polavarapu ◽  
Veeramani Preethish-Kumar ◽  
Seena Vengalil ◽  
Saraswati Nashi ◽  
Mallika Lavania ◽  
...  

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