Long-Lasting and Efficient Tumor Imaging Using a High Relaxivity Polysaccharide Nanogel Magnetic Resonance Imaging Contrast Agent

2015 ◽  
Vol 16 (9) ◽  
pp. 2964-2971 ◽  
Author(s):  
Minnie Chan ◽  
Jacques Lux ◽  
Tomoki Nishimura ◽  
Kazunari Akiyoshi ◽  
Adah Almutairi
2008 ◽  
Vol 61 (9) ◽  
pp. 682 ◽  
Author(s):  
Stéphane Dumas ◽  
Jeffrey S. Troughton ◽  
Normand J. Cloutier ◽  
Jaclyn M. Chasse ◽  
Thomas J. McMurry ◽  
...  

EP-647 is a serum albumin-targeted magnetic resonance imaging contrast agent comprising a GdDTPA (DTPA, diethylenetriaminepentaacetate) chelate for magnetic resonance signal generation linked via a phosphodiester to a substituted biphenyl for albumin targeting. Albumin binding and relaxivity are higher than the benchmark magnetic resonance angiographic agent MS-325. EP-647 binds primarily to a unique site on serum albumin that is different from the MS-325 site and the binding sites of other drugs.


2019 ◽  
Vol 55 (4) ◽  
pp. 478-481 ◽  
Author(s):  
Jiaomin Lin ◽  
Pengyan Xin ◽  
Lu An ◽  
Yanjun Xu ◽  
Cheng Tao ◽  
...  

Fe3O4 nanoparticles were assembled into a zeolitic-imidazole framework to form a pH- and glutathione-responsive T2–T1 switching contrast agent for sensitive tumor imaging.


2002 ◽  
Vol 9 (9) ◽  
pp. 1027-1032 ◽  
Author(s):  
Kenjiro Hanaoka ◽  
Kazuya Kikuchi ◽  
Yasuteru Urano ◽  
Michiko Narazaki ◽  
Takashi Yokawa ◽  
...  

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