Permanganate Oxidation of DNA Nucleotides: An Introductory Redox Laboratory Framed as a Murder Mystery

2018 ◽  
Vol 95 (10) ◽  
pp. 1840-1847 ◽  
Author(s):  
Stephen M. Testa ◽  
John P. Selegue ◽  
April French ◽  
Brett Criswell
Keyword(s):  
Permanganate Oxidation ◽  
Oxidation Of Dna

8-Hydroxyguanine Is Not Produced by Permanganate Oxidation of DNA

1994 ◽  
Vol 311 (2) ◽  
pp. 523-524 ◽  
Author(s):  
T. Nawamura ◽  
K. Negishi ◽  
H. Hayatsu
Keyword(s):  
Permanganate Oxidation ◽  
Oxidation Of Dna

p-Cyano substituted 5-benzoyldeoxyuridine as a novel electron-accepting nucleobase for one-electron oxidation of DNA

1998 ◽  
Vol 39 (33) ◽  
pp. 5995-5998 ◽  
Author(s):  
Kazuhiko Nakatani ◽  
Kazuhiko Fujisawa ◽  
Chikara Dohno ◽  
Takashi Nakamura ◽  
Isao Saito
Keyword(s):  
Oxidation Of Dna

The Mechanism of Permanganate Oxidation of Sulfides and Sulfoxides

2011 ◽  
Vol 77 (1) ◽  
pp. 351-356 ◽  
Author(s):  
Arumugam Jayaraman ◽  
Allan L. L. East
Keyword(s):  
Permanganate Oxidation ◽  
Oxidation Of Sulfides

scholarly journals Oxidative damage to DNA: Inhibition of guanine damage

2006 ◽  
Vol 78 (12) ◽  
pp. 2297-2304 ◽  
Author(s):  
Sriram Kanvah ◽  
Gary B. Schuster
Keyword(s):  
Oxidative Damage ◽  
Structural Changes ◽  
Global Structure ◽  
Chemical Damage ◽  
Oxidation Of Dna ◽  
Anthraquinone Derivatives ◽  
Covalently Linked ◽  
The One ◽  
Oxidative Damage To Dna ◽  
Dna Inhibition

One-electron oxidation of DNA results in chemical damage to nucleobases, particularly guanine in multiple G sequences. Oxidation may be triggered by numerous events, including photosensitization. We describe studies of photoinduced oxidations of DNA triggered by irradiation of covalently linked anthraquinone derivatives under various conditions that affect the global structure of the DNA. These structural changes have subtle effects on the result of the one-electron oxidation.

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