Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device

Nano Letters ◽  
2021 ◽  
Author(s):  
Sarah J. Shepherd ◽  
Claude C. Warzecha ◽  
Sagar Yadavali ◽  
Rakan El-Mayta ◽  
Mohamad-Gabriel Alameh ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Nanoparticle Production ◽  
Lipid Nanoparticle

scholarly journals Three-dimensional, symmetrically assembled microfluidic device for lipid nanoparticle production

RSC Advances ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 1430-1439
Author(s):  
Niko Kimura ◽  
Masatoshi Maeki ◽  
Kosuke Sasaki ◽  
Yusuke Sato ◽  
Akihiko Ishida ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Three Dimensional ◽  
Size Control ◽  
Lipid Nanoparticles ◽  
Nanoparticle Production ◽  
Lipid Nanoparticle

We developed a three-dimensional and symmetrically assembled microfluidic device named the 3D-iLiNP device. The 3D-iLiNP device allowed the precise size control of sub-100 nm sized lipid nanoparticles by the homogeneous and slow ethanol dilution.

Tucumã (Astrocaryum vulgare) fat: an Amazonian material as a pharmaceutical input for lipid nanoparticle production

2020 ◽  
Author(s):  
Antonio Taylon Aguiar Gomes ◽  
Rayanne Rocha Pereira ◽  
Anivaldo Pereira Duarte Junior ◽  
Antonio Manoel da Cruz Rodrigues ◽  
Claudio Marcio Rocha Remédios ◽  
...  
Keyword(s):  
Nanoparticle Production ◽  
Lipid Nanoparticle

Cationic lipid nanoparticle production by microfluidization for siRNA delivery

2021 ◽  
pp. 120772
Author(s):  
Xiaojing Liu ◽  
Badr Bahloul ◽  
René Lai Kuen ◽  
Karine Andrieux ◽  
Caroline Roques ◽  
...  
Keyword(s):  
Sirna Delivery ◽  
Cationic Lipid ◽  
Nanoparticle Production ◽  
Lipid Nanoparticle

Size-controlled lipid nanoparticle production using turbulent mixing to enhance oral DNA delivery

2018 ◽  
Vol 81 ◽  
pp. 195-207 ◽  
Author(s):  
Zhiyu He ◽  
Yizong Hu ◽  
Tianqi Nie ◽  
Haoyu Tang ◽  
Jinchang Zhu ◽  
...  
Keyword(s):  
Turbulent Mixing ◽  
Dna Delivery ◽  
Nanoparticle Production ◽  
Lipid Nanoparticle ◽  
Size Controlled

Novel Microfluidic Device Integrated with a Fluidic-Capacitor to Mimic Heart Beating for Generation of Functional Liver Organoids

2019 ◽  
Vol 139 (7) ◽  
pp. 209-216
Author(s):  
Jiaxu Wu ◽  
Yoshikazu Hirai ◽  
Ken-ichiro Kamei ◽  
Toshiyuki Tsuchiya ◽  
Osamu Tabata
Keyword(s):  
Microfluidic Device ◽  
Heart Beating ◽  
Liver Organoids

Pneumatically-driven Microfluidic Device for Evaluating Active Transport by Kinesin Motor Protein

2016 ◽  
Vol 136 (9) ◽  
pp. 384-389
Author(s):  
Kazuya Fujimoto ◽  
Hirofumi Shintaku ◽  
Hidetoshi Kotera ◽  
Ryuji Yokokawa
Keyword(s):  
Active Transport ◽  
Microfluidic Device ◽  
Motor Protein ◽  
Kinesin Motor
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