scholarly journals Three-dimensional, symmetrically assembled microfluidic device for lipid nanoparticle production

RSC Advances ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 1430-1439
Author(s):  
Niko Kimura ◽  
Masatoshi Maeki ◽  
Kosuke Sasaki ◽  
Yusuke Sato ◽  
Akihiko Ishida ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Three Dimensional ◽  
Size Control ◽  
Lipid Nanoparticles ◽  
Nanoparticle Production ◽  
Lipid Nanoparticle

We developed a three-dimensional and symmetrically assembled microfluidic device named the 3D-iLiNP device. The 3D-iLiNP device allowed the precise size control of sub-100 nm sized lipid nanoparticles by the homogeneous and slow ethanol dilution.

Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device

Nano Letters ◽  
2021 ◽  
Author(s):  
Sarah J. Shepherd ◽  
Claude C. Warzecha ◽  
Sagar Yadavali ◽  
Rakan El-Mayta ◽  
Mohamad-Gabriel Alameh ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Nanoparticle Production ◽  
Lipid Nanoparticle

scholarly journals Development of a human neuromuscular tissue-on-a-chip model on a 24-well-plate-format compartmentalized microfluidic device

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Kazuki Yamamoto ◽  
Nao Yamaoka ◽  
Yu Imaizumi ◽  
Takunori Nagashima ◽  
Taiki Furutani ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Microfluidic Device ◽  
Motor Neurons ◽  
Muscle Fibers ◽  
Three Dimensional ◽  
Tissue Model ◽  
Skeletal Muscle Fibers

A three-dimensional human neuromuscular tissue model that mimics the physically separated structures of motor neurons and skeletal muscle fibers is presented.

scholarly journals A Three-Dimensional Microfluidic Device for Monitoring Cancer and Chemotherapy-Associated Platelet Activation

ACS Omega ◽  
2021 ◽  
Vol 6 (4) ◽  
pp. 3164-3172
Author(s):  
Zhujing Hao ◽  
Haichen Lv ◽  
Ruopeng Tan ◽  
Xiaolei Yang ◽  
Yang Liu ◽  
...  
Keyword(s):  
Platelet Activation ◽  
Microfluidic Device ◽  
Three Dimensional

Formation of Copolymer-Ag Nanoparticles Composite Micelles in Three-dimensional Co-flow Focusing Microfluidic Device

2019 ◽  
Vol 34 (6) ◽  
pp. 1259-1265
Author(s):  
Mengran Feng ◽  
Guangyao He ◽  
Si Yi ◽  
Weizheng Song ◽  
Yanjun Chen ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Ag Nanoparticles ◽  
Three Dimensional ◽  
Flow Focusing

scholarly journals Melamine promotes calcium crystal formation in three-dimensional microfluidic device

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Farai Gombedza ◽  
Sade Evans ◽  
Samuel Shin ◽  
Eugenia Awuah Boadi ◽  
Qian Zhang ◽  
...  
Keyword(s):  
Microfluidic Device ◽  
Three Dimensional ◽  
Crystal Formation

scholarly journals Three-dimensional (3D) extra-cellular matrix coating of a microfluidic device

2006 ◽  
Vol 34 ◽  
pp. 747-751 ◽  
Author(s):  
K C Chaw ◽  
M Manimaran ◽  
Francis E H Tay ◽  
S Swaminathan
Keyword(s):  
Microfluidic Device ◽  
Three Dimensional ◽  
Extra Cellular Matrix ◽  
Cellular Matrix

scholarly journals Tunable structural color of bottlebrush block copolymers through direct-write 3D printing from solution

2020 ◽  
Vol 6 (24) ◽  
pp. eaaz7202 ◽  
Author(s):  
Bijal B. Patel ◽  
Dylan J. Walsh ◽  
Do Hoon Kim ◽  
Justin Kwok ◽  
Byeongdu Lee ◽  
...  
Keyword(s):  
3D Printing ◽  
Self Assembly ◽  
Three Dimensional ◽  
Size Control ◽  
Functional Materials ◽  
Domain Size ◽  
Direct Write ◽  
Processing Scheme ◽  
Solvent Vapor ◽  
Robust Processing

Additive manufacturing of functional materials is limited by control of microstructure and assembly at the nanoscale. In this work, we integrate nonequilibrium self-assembly with direct-write three-dimensional (3D) printing to prepare bottlebrush block copolymer (BBCP) photonic crystals (PCs) with tunable structure color. After varying deposition conditions during printing of a single ink solution, peak reflected wavelength for BBCP PCs span a range of 403 to 626 nm (blue to red), corresponding to an estimated change in d-spacing of >70 nm (Bragg- Snell equation). Physical characterization confirms that these vivid optical effects are underpinned by tuning of lamellar domain spacing, which we attribute to modulation of polymer conformation. Using in situ optical microscopy and solvent-vapor annealing, we identify kinetic trapping of metastable microstructures during printing as the mechanism for domain size control. More generally, we present a robust processing scheme with potential for on-the-fly property tuning of a variety of functional materials.

scholarly journals Synthesis of Copper Nanoparticles Using Glass Microfluidic Device

Proceedings ◽  
2018 ◽  
Vol 2 (13) ◽  
pp. 1110
Author(s):  
Yiyang Liang ◽  
Yoko Shinozaki ◽  
Hiromasa Yagyu
Keyword(s):  
Particle Size ◽  
Ascorbic Acid ◽  
Microfluidic Device ◽  
Copper Nanoparticles ◽  
Flow Rate ◽  
Control Method ◽  
Size Control ◽  
Metallic Materials ◽  
First Time ◽  
Citrate Reduction

In a synthesis of gold nanoparticles on a microfluidic device by citrate reduction, a particle size control by changing a flow rate was reported. To apply this simple control method to the synthesis of other metallic materials, we propose the synthesis of copper nanoparticles (CuNPs) in ethylene glycol by the microfluidic device using ascorbic acid as both antioxidant and reducing agent. The experimental results found for the first time that the effect of the flow rate of agents on particle size of the synthesized CuNPs in the device.

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