Elusive Impurities—Evidence versus Hypothesis. Technical and Regulatory Update on Alkyl Sulfonates in Sulfonic Acid Salts

2019 ◽  
Vol 23 (5) ◽  
pp. 695-710 ◽  
Author(s):  
David J. Snodin
Keyword(s):  
Sulfonic Acid ◽  
Alkyl Sulfonates ◽  
Regulatory Update ◽  
Acid Salts

Sulfonic Acid Salts of Donepezil and Stabilization of Amorphous Donepezil via Formation of Amorphous Salts

2015 ◽  
Vol 15 (7) ◽  
pp. 3123-3130 ◽  
Author(s):  
Sun Hye Lee ◽  
Jae Ho Bae ◽  
Yeojin Park ◽  
Bishal Raj Adhikari ◽  
Chen Mao ◽  
...  
Keyword(s):  
Sulfonic Acid ◽  
Acid Salts

Infrared Spectra of Zinc Sulfinates

1969 ◽  
Vol 23 (4) ◽  
pp. 337-341 ◽  
Author(s):  
James P. Weidner ◽  
Seymour S. Block
Keyword(s):  
Infrared Spectra ◽  
Sulfonic Acid ◽  
The Other ◽  
No Absorption ◽  
Acid Salts

The infrared spectra of 15 aliphatic and aromatic zinc sulfinates are given. With zinc p-toluene-sulfinate, run neat as an extremely thin, flat crystal, the symmetric and asymmetric S → 0 peaks were clearly visible at 10.1 μ (990 cm−1) and 10.6 μ (943 cm−1), respectively, and similar absorptions were obtained for the other sulfinates run as Nujol mulls. In distinction to sulfonic acid salts, the sulfinates have practically no absorption in the 8–9 μ (1250–1110 cm−1) region, whereas the sulfonates have no absorption in the 10–11 μ (1000–910 cm−1) thus indicating the analytical value of the spectra in distinguishing these two groups of compounds.

ChemInform Abstract: ALKALINE FUSION OF A MIXTURE OF AROMATIC SULFONIC ACID SALTS

1979 ◽  
Vol 10 (35) ◽  
Author(s):  
A. Z. SAIFUTDINOV ◽  
A. Z. BIKKULOV ◽  
G. F. YUKHNO
Keyword(s):  
Sulfonic Acid ◽  
Alkaline Fusion ◽  
Acid Salts

scholarly journals 1,2-Naphthoquinone-4-sulfonic acid salts in organic synthesis

2022 ◽  
Vol 18 ◽  
pp. 53-69
Author(s):  
Ruan Carlos B Ribeiro ◽  
Patricia G Ferreira ◽  
Amanda de A Borges ◽  
Luana da S M Forezi ◽  
Fernando de Carvalho da Silva ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Organic Synthesis ◽  
Sulfonic Acid ◽  
Pharmaceutical Market ◽  
Low Molecular Weight ◽  
Amino Groups ◽  
Pharmacological Targets ◽  
Secondary Amino ◽  
Acid Salts

Several low molecular weight naphthoquinones are very useful in organic synthesis. These compounds have given rise to thousands of other naphthoquinones that have been tested against various microorganisms and pharmacological targets, including being used in the preparation of several drugs that are on the pharmaceutical market. Among these naphthoquinones, the series of compounds prepared from 1,2-naphthoquinone-4-sulfonic acid salts (β-NQS) stands out. In addition to being used in organic synthesis, they are excellent analytical derivatization reagents to spectrophotometrically determine drugs containing primary and secondary amino groups. This review summarizes the literature involving β-NQS.

Sign in / Sign up

Export Citation Format

Share Document