scholarly journals Recovery of Active Pharmaceutical Ingredients from Unused Solid Dosage-Form Drugs

ACS Omega ◽  
2020 ◽  
Vol 5 (45) ◽  
pp. 29147-29157
Author(s):  
Dhanang Edy Pratama ◽  
Wen-Chen Hsieh ◽  
Ahmed Elmaamoun ◽  
Hung Lin Lee ◽  
Tu Lee
2020 ◽  
Vol 143 ◽  
pp. 105176 ◽  
Author(s):  
Christos I. Gioumouxouzis ◽  
Emmanouil Tzimtzimis ◽  
Orestis L. Katsamenis ◽  
Anthi Dourou ◽  
Catherine Markopoulou ◽  
...  

2021 ◽  
Vol 3 (1) ◽  
pp. 20
Author(s):  
Iyan Sopyan ◽  
Rizka Guntina Khairunisa

SeDem System is a new system that can be applied in solid dosage form preformulation studies of medicines. It have parameters to evaluates critical quality attributes of materials that have an impact on final drug product’s quality. SeDeM studies could be used as a method for identifying the best excipient and calculating the maximum amount of excipient required for formulation. SeDeM method can , providing formulation with the lowest amount of excipients as it combines the Active Pharmaceutical Ingredients (API) with only one excipient and the standard formula of lubricants, thus avoiding the used of unnecessary excipients, such as diluents, binders and agglutinants. The information given by the SeDeM system contributes to a quality by drug design development.Keywords: SeDeM System, Excipients


2020 ◽  
Vol 2 (2) ◽  
pp. 42
Author(s):  
Margaretha Efa Putri ◽  
Anis Yohana Chaerunisaa ◽  
Marline Abdassah

Cellulose nanocrystals is a cellulose derivates which has been widely researched and observed as an chemical agent. Different with cellulose that has been widely used as pharmaceutical excipient especially in solid dosage form, cellulose in nanocrystals form is not available in pharmaceutical grade. Cellulose nanocrystals have different characteristics and quality which is depend on its preparation including sourcing, isolation procedure, and hydrolysis reaction involved. This difference is very important to deeply observed its impact in pharmaceutical dosage form with different active ingredients. In addition, cellulose nanocrystals should meet FDA requirement as pharmaceutical excipient. This review  describe cellulose nanocrystals preparation and its characteristics, its application to active pharmaceutical ingredients, and its properties in order to meet FDA requirement.Keywords: Cellulose, nanocrystals, pharmaceutical excipient


2016 ◽  
Vol 15 (3) ◽  
pp. 613
Author(s):  
Mani Ganesh ◽  
Abidov Sh Aziz ◽  
Mei Mei Peng ◽  
Ramaswamy Ravikumar ◽  
Kalaimani Sakthimanigandan ◽  
...  

Author(s):  
Puranik Manisha ◽  
Shambharkar Samta ◽  
Nimbalkar Shantanu ◽  
Mahapatra Debarshi Kar

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