scholarly journals Fabrication of an osmotic 3D printed solid dosage form for controlled release of active pharmaceutical ingredients

2020 ◽  
Vol 143 ◽  
pp. 105176 ◽  
Author(s):  
Christos I. Gioumouxouzis ◽  
Emmanouil Tzimtzimis ◽  
Orestis L. Katsamenis ◽  
Anthi Dourou ◽  
Catherine Markopoulou ◽  
...  
Keyword(s):  
Controlled Release ◽  
Dosage Form ◽  
Active Pharmaceutical Ingredients ◽  
Solid Dosage Form ◽  
Pharmaceutical Ingredients ◽  
Solid Dosage ◽  
3D Printed

scholarly journals Recovery of Active Pharmaceutical Ingredients from Unused Solid Dosage-Form Drugs

ACS Omega ◽  
2020 ◽  
Vol 5 (45) ◽  
pp. 29147-29157
Author(s):  
Dhanang Edy Pratama ◽  
Wen-Chen Hsieh ◽  
Ahmed Elmaamoun ◽  
Hung Lin Lee ◽  
Tu Lee
Keyword(s):  
Dosage Form ◽  
Active Pharmaceutical Ingredients ◽  
Solid Dosage Form ◽  
Pharmaceutical Ingredients ◽  
Solid Dosage

scholarly journals Mini Review : Sedem System as a Tool to Characterize Excipients in Solid Dosage Form

2021 ◽  
Vol 3 (1) ◽  
pp. 20
Author(s):  
Iyan Sopyan ◽  
Rizka Guntina Khairunisa
Keyword(s):  
Drug Design ◽  
Dosage Form ◽  
Maximum Amount ◽  
Active Pharmaceutical Ingredients ◽  
Critical Quality Attributes ◽  
Solid Dosage Form ◽  
Pharmaceutical Ingredients ◽  
Solid Dosage ◽  
Preformulation Studies ◽  
New System

SeDem System is a new system that can be applied in solid dosage form preformulation studies of medicines. It have parameters to evaluates critical quality attributes of materials that have an impact on final drug product’s quality. SeDeM studies could be used as a method for identifying the best excipient and calculating the maximum amount of excipient required for formulation. SeDeM method can , providing formulation with the lowest amount of excipients as it combines the Active Pharmaceutical Ingredients (API) with only one excipient and the standard formula of lubricants, thus avoiding the used of unnecessary excipients, such as diluents, binders and agglutinants. The information given by the SeDeM system contributes to a quality by drug design development.Keywords: SeDeM System, Excipients

A 3D printed bilayer oral solid dosage form combining metformin for prolonged and glimepiride for immediate drug delivery

2018 ◽  
Vol 120 ◽  
pp. 40-52 ◽  
Author(s):  
Christos I. Gioumouxouzis ◽  
Apostolos Baklavaridis ◽  
Orestis L. Katsamenis ◽  
Catherine K. Markopoulou ◽  
Nikolaos Bouropoulos ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Dosage Form ◽  
Solid Dosage Form ◽  
Solid Dosage ◽  
3D Printed

scholarly journals Cellulose Nanocrystals Preparation as Pharmaceuticals Excipient : a Review

2020 ◽  
Vol 2 (2) ◽  
pp. 42
Author(s):  
Margaretha Efa Putri ◽  
Anis Yohana Chaerunisaa ◽  
Marline Abdassah
Keyword(s):  
Cellulose Nanocrystals ◽  
Dosage Form ◽  
Isolation Procedure ◽  
Chemical Agent ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Dosage Form ◽  
Pharmaceutical Excipient ◽  
Pharmaceutical Ingredients ◽  
Solid Dosage ◽  
Different Characteristics

Cellulose nanocrystals is a cellulose derivates which has been widely researched and observed as an chemical agent. Different with cellulose that has been widely used as pharmaceutical excipient especially in solid dosage form, cellulose in nanocrystals form is not available in pharmaceutical grade. Cellulose nanocrystals have different characteristics and quality which is depend on its preparation including sourcing, isolation procedure, and hydrolysis reaction involved. This difference is very important to deeply observed its impact in pharmaceutical dosage form with different active ingredients. In addition, cellulose nanocrystals should meet FDA requirement as pharmaceutical excipient. This review  describe cellulose nanocrystals preparation and its characteristics, its application to active pharmaceutical ingredients, and its properties in order to meet FDA requirement.Keywords: Cellulose, nanocrystals, pharmaceutical excipient

scholarly journals Evaluation of Tropaeolin 000-1 as a Colorimetric Reagent for Assay of Duloxetine and Escitalopram in Solid Dosage Form

2016 ◽  
Vol 15 (3) ◽  
pp. 613
Author(s):  
Mani Ganesh ◽  
Abidov Sh Aziz ◽  
Mei Mei Peng ◽  
Ramaswamy Ravikumar ◽  
Kalaimani Sakthimanigandan ◽  
...  
Keyword(s):  
Dosage Form ◽  
Solid Dosage Form ◽  
Solid Dosage ◽  
Colorimetric Reagent
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