Hydrotalcite-Supported Cobalt Phosphide Nanorods as a Highly Active and Reusable Heterogeneous Catalyst for Ammonia-Free Selective Hydrogenation of Nitriles to Primary Amines

A well-defined nano-cobalt phosphide serves as an air-stable, highly active and reusable heterogeneous catalyst for the selective hydrogenation of nitriles to primary amines under mild reaction conditions.

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Selective Hydrogenation of Nitriles to Primary Amines Catalyzed by a Cobalt Pincer Complex

Journal of the American Chemical Society ◽

10.1021/jacs.5b04879 ◽

2015 ◽

Vol 137 (28) ◽

pp. 8888-8891 ◽

Cited By ~ 160

Author(s):

Arup Mukherjee ◽

Dipankar Srimani ◽

Subrata Chakraborty ◽

Yehoshoa Ben-David ◽

David Milstein

Keyword(s):

Selective Hydrogenation ◽

Primary Amines ◽

Pincer Complex ◽

Hydrogenation Of Nitriles

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A New Supported Rhodium Catalyst for Selective Hydrogenation of Nitriles to Primary Amines

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc20070468 ◽

2007 ◽

Vol 72 (4) ◽

pp. 468-474 ◽

Cited By ~ 6

Author(s):

Peter T. Witte

Keyword(s):

Selective Hydrogenation ◽

High Selectivity ◽

Rhodium Catalyst ◽

Primary Amines ◽

Mild Conditions ◽

Pharmaceutical Applications ◽

Strong Acids ◽

Hydrogenation Of Nitriles ◽

Supported Rhodium Catalyst

Nitriles are converted to primary amines with high selectivity using a newly developed alumina-supported rhodium catalyst. The high selectivity is obtained without any additives, which are often used to prevent the formation of higher amines. The catalyst is active under mild conditions in various solvents, which makes it specifically suitable for use in pharmaceutical applications or for other substrates that can react with additives like strong acids or bases.

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Selective hydrogenation of nitriles to primary amines catalyzed by a novel iron complex

Chemical Communications ◽

10.1039/c5cc08204h ◽

2016 ◽

Vol 52 (9) ◽

pp. 1812-1815 ◽

Cited By ~ 76

Author(s):

Subrata Chakraborty ◽

Gregory Leitus ◽

David Milstein

Keyword(s):

Selective Hydrogenation ◽

Iron Complex ◽

Primary Amines ◽

Homogeneous Hydrogenation ◽

Earth Abundant ◽

Novel Complex ◽

Aliphatic Nitriles ◽

Hydrogenation Of Nitriles

A novel complex based on earth-abundant iron, and its application in the catalytic homogeneous hydrogenation of (hetero)aromatic, benzylic, and aliphatic nitriles to selectively form primary amines is discovered.

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Mild palladium-catalysed highly efficient hydrogenation of CN, C–NO2, and CO bonds using H2 of 1 atm in H2O

Green Chemistry ◽

10.1039/c8gc03285h ◽

2019 ◽

Vol 21 (4) ◽

pp. 830-838 ◽

Cited By ~ 10

Author(s):

Yaxu Liu ◽

Shaopo He ◽

Ziyi Quan ◽

Huizhuo Cai ◽

Yang Zhao ◽

...

Keyword(s):

Selective Hydrogenation ◽

High Efficiency ◽

Nitro Compounds ◽

Primary Amines ◽

Highly Efficient ◽

Hydrogenation Of Nitriles

Here we present the first example of a mild and high-efficiency protocol enabling a process in water using 1 atm of H2 for the efficient and selective hydrogenation of nitriles, nitro compounds, ketones, and aldehydes to yield primary amines and alcohols with satisfactory yields of up to >99%.

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