Complete amino acid sequence of streptokinase and its homology with serine proteases

Biochemistry ◽  
1982 ◽  
Vol 21 (26) ◽  
pp. 6620-6625 ◽  
Author(s):  
Kenneth W. Jackson ◽  
Jordan Tang
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Serine Proteases ◽  
Complete Amino Acid Sequence

The complete amino acid sequence of rat submaxillary gland tonin does contain the aspartic acid at the active site: confirmation by protein sequence analyses

1987 ◽  
Vol 65 (4) ◽  
pp. 321-337 ◽  
Author(s):  
C. Lazure ◽  
R. Leduc ◽  
N. G. Seidah ◽  
G. Thibault ◽  
J. Genest ◽  
...  
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Active Site ◽  
Serine Proteases ◽  
Submaxillary Gland ◽  
Catalytic Triad ◽  
Complete Amino Acid Sequence ◽  
Molecular Weights ◽  
Amino Acid Peptide ◽  
Close Relationship

The revised amino acid sequence of rat submaxillary gland tonin, a serine protease, does contain the active site Asp residue. The active site of this kallikrein-related enzyme is thus made up of the same catalytic triad (Asp, Ser, and His) found in all known serine proteases. The important Asp residue has now been localized in a 16 amino acid peptide previously reported as missing in the tonin sequence. The complete amino acid sequence thus contains 235 residues corresponding to a molecular weight of 25 658, more in agreement with previously reported molecular weights. Moreover, the revised structure led (a) to the assignment of Arg, Asn, and Val residues instead of His, Asp, and Gly at positions 63, 165, and 169, respectively; (b) to the assignment of residues occupying an overlapping sequence at positions 165–171, and finally (c) to the localization of two N-glycosylation sites at positions 82 and 165. These results further document the close relationship of tonin to the ever expanding kallikrein family.

scholarly journals The complete amino acid sequence of the low molecular weight cytosolic acid phosphatase

1989 ◽  
Vol 264 (5) ◽  
pp. 2560-2567
Author(s):  
G Camici ◽  
G Manao ◽  
G Cappugi ◽  
A Modesti ◽  
M Stefani ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Acid Phosphatase ◽  
Amino Acid ◽  
Amino Acid Sequence ◽  
Low Molecular Weight ◽  
Complete Amino Acid Sequence

scholarly journals Complete amino acid sequence of an integrin beta subunit (beta 7) identified in leukocytes

1991 ◽  
Vol 266 (17) ◽  
pp. 11009-11016 ◽  
Author(s):  
D.J. Erle ◽  
C. Rüegg ◽  
D. Sheppard ◽  
R. Pytela
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Beta Subunit ◽  
Complete Amino Acid Sequence
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