Quantitative Analysis of the Relative Contributions of Donor Acyl Carrier Proteins, Acceptor Ketosynthases, and Linker Regions to Intermodular Transfer of Intermediates in Hybrid Polyketide Synthases†

Biochemistry ◽  
2002 ◽  
Vol 41 (15) ◽  
pp. 5056-5066 ◽  
Author(s):  
Nicholas Wu ◽  
David E. Cane ◽  
Chaitan Khosla
Keyword(s):  
Quantitative Analysis ◽  
Polyketide Synthases ◽  
Carrier Proteins ◽  
Acyl Carrier Proteins

scholarly journals Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins.

1993 ◽  
Vol 175 (8) ◽  
pp. 2197-2204 ◽  
Author(s):  
C Khosla ◽  
R McDaniel ◽  
S Ebert-Khosla ◽  
R Torres ◽  
D H Sherman ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Polyketide Synthases ◽  
Carrier Proteins ◽  
Acyl Carrier Proteins

scholarly journals Recognition of acyl carrier proteins by ketoreductases in assembly line polyketide synthases

2016 ◽  
Vol 69 (7) ◽  
pp. 507-510 ◽  
Author(s):  
Matthew P Ostrowski ◽  
David E Cane ◽  
Chaitan Khosla
Keyword(s):  
Assembly Line ◽  
Polyketide Synthases ◽  
Carrier Proteins ◽  
Acyl Carrier Proteins

scholarly journals Protein−Protein Recognition between Acyltransferases and Acyl Carrier Proteins in Multimodular Polyketide Synthases

Biochemistry ◽  
2010 ◽  
Vol 49 (1) ◽  
pp. 95-102 ◽  
Author(s):  
Fong T. Wong ◽  
Alice Y. Chen ◽  
David E. Cane ◽  
Chaitan Khosla
Keyword(s):  
Polyketide Synthases ◽  
Protein Recognition ◽  
Carrier Proteins ◽  
Acyl Carrier Proteins

scholarly journals Acyl hydrolases from trans-AT polyketide synthases target acetyl units on acyl carrier proteins

2016 ◽  
Vol 52 (30) ◽  
pp. 5262-5265 ◽  
Author(s):  
Matthew Jenner ◽  
Jose P. Afonso ◽  
Christoph Kohlhaas ◽  
Petra Karbaum ◽  
Sarah Frank ◽  
...  
Keyword(s):  
Polyketide Synthases ◽  
Carrier Proteins ◽  
Acyl Carrier Proteins

Acyl hydrolase (AH) domains are a common feature oftrans-AT PKSs, perform a proofreading function by removing principally acetyl chains from stalled sites.

scholarly journals Structure, function and dynamics in acyl carrier proteins

PLoS ONE ◽  
2019 ◽  
Vol 14 (7) ◽  
pp. e0219435 ◽  
Author(s):  
Rohit Farmer ◽  
Christopher Morton Thomas ◽  
Peter James Winn
Keyword(s):  
Structure Function ◽  
Carrier Proteins ◽  
Acyl Carrier Proteins

scholarly journals The effect of divalent cations on the thermostability of type II polyketide synthase acyl carrier proteins

AIChE Journal ◽  
2018 ◽  
Vol 64 (12) ◽  
pp. 4308-4318 ◽  
Author(s):  
Marco A. Rivas ◽  
Valentine C. Courouble ◽  
Miranda C. Baker ◽  
David L. Cookmeyer ◽  
Kristen E. Fiore ◽  
...  
Keyword(s):  
Polyketide Synthase ◽  
Divalent Cations ◽  
Type Ii ◽  
Carrier Proteins ◽  
Acyl Carrier Proteins

scholarly journals Evolutionary significance of self-acylation property in acyl carrier proteins

IUBMB Life ◽  
2009 ◽  
Vol 61 (8) ◽  
pp. 853-859 ◽  
Author(s):  
Ashish Misra ◽  
Namita Surolia ◽  
Avadhesha Surolia
Keyword(s):  
Evolutionary Significance ◽  
Carrier Proteins ◽  
Acyl Carrier Proteins
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