Multistep One-Pot Reactions Combining Biocatalysts and Chemical Catalysts for Asymmetric Synthesis

ACS Catalysis ◽  
2013 ◽  
Vol 3 (12) ◽  
pp. 2856-2864 ◽  
Author(s):  
Carl A. Denard ◽  
John F. Hartwig ◽  
Huimin Zhao
Keyword(s):  
Asymmetric Synthesis ◽  
One Pot

Indium Bromide-catalyzed Unprecedented Hydrogenolysis: A Novel One-Pot Synthesis of Per-O-Acetylated β-carboxymethyl O and S-glycosides

2020 ◽  
Vol 24 (8) ◽  
pp. 900-908
Author(s):  
Ram Naresh Yadav ◽  
Amrendra K Singh ◽  
Bimal Banik
Keyword(s):  
Asymmetric Synthesis ◽  
Chiral Auxiliary ◽  
Bioactive Molecules ◽  
One Pot ◽  
Enantiomerically Pure ◽  
Stereoselective Glycosylation ◽  
One Pot Synthesis ◽  
Wide Range

Numerous O (oxa)- and S (thia)-glycosyl esters and their analogous glycosyl acids have been accomplished through stereoselective glycosylation of various peracetylated bromo sugar with benzyl glycolate using InBr3 as a glycosyl promotor followed by in situ hydrogenolysis of resulting glycosyl ester. A tandem glycosylating and hydrogenolytic activity of InBr3 has been successfully investigated in a one-pot procedure. The resulting synthetically valuable and virtually unexplored class of β-CMGL (glycosyl acids) could serve as an excellent potential chiral auxiliary in the asymmetric synthesis of a wide range of enantiomerically pure medicinally prevalent β-lactams and other bioactive molecules of diverse medicinal interest.

Asymmetric synthesis of dihydrocarbazoles through Friedel-Crafts alkylation/annulation sequential reaction of indoles

2021 ◽  
Author(s):  
Linfeng Hu ◽  
Weidi Cao ◽  
Kaixuan Wang ◽  
Xiaohua Liu ◽  
Xiaoming Feng
Keyword(s):  
Asymmetric Synthesis ◽  
One Pot ◽  
Sequential Reaction

An enantioselective tandem Friedel-Crafts alkylation/annulation of indoles with diazoacetoacetate enones is realized in one pot. A series of dihydrocarbazoles were obtained in moderate yields with good to excellent ee values...

One-Pot Asymmetric Synthesis of 2- and 2,3-Disubstituted Tetrahydrofuran Derivatives

2012 ◽  
Vol 77 (12) ◽  
pp. 5394-5398 ◽  
Author(s):  
P. Veeraraghavan Ramachandran ◽  
Hari N. G. Nair ◽  
Pravin D. Gagare
Keyword(s):  
Asymmetric Synthesis ◽  
One Pot

scholarly journals Recyclable Organocatalyst for One-Pot Asymmetric Synthesis of Dihydrofuranone and Tetrahydropyranone Spirooxindoles

2018 ◽  
Vol 2019 (1) ◽  
pp. 150-155 ◽  
Author(s):  
Miao Liu ◽  
Xiaofeng Zhang ◽  
Xin Huang ◽  
Gagan Dhawan ◽  
Jason Evans ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
One Pot

ChemInform Abstract: One-Pot Catalytic Asymmetric Synthesis of Pyranones.

ChemInform ◽  
2009 ◽  
Vol 40 (46) ◽  
Author(s):  
Kevin Cheng ◽  
Ann Rowley Kelly ◽  
Rachel A. Kohn ◽  
Jessica F. Dweck ◽  
Patrick J. Walsh
Keyword(s):  
Asymmetric Synthesis ◽  
One Pot ◽  
Catalytic Asymmetric Synthesis ◽  
Catalytic Asymmetric

A One-Pot Asymmetric Synthesis of a N-Acylated 4,5-Dihydropyrazole, A Key Intermediate of Thrombin Inhibitor AZD8165

2014 ◽  
Vol 18 (8) ◽  
pp. 969-975 ◽  
Author(s):  
Staffan Karlsson ◽  
Jonas Brånalt ◽  
Maria Ölwegård Halvarsson ◽  
Joakim Bergman
Keyword(s):  
Asymmetric Synthesis ◽  
Thrombin Inhibitor ◽  
One Pot

scholarly journals Asymmetric Synthesis of Highly Functionalized Tetrahydropyrans via a One-Pot Organocatalytic Michael/Henry/Ketalization Sequence

2014 ◽  
Vol 16 (14) ◽  
pp. 3636-3639 ◽  
Author(s):  
Robert Hahn ◽  
Gerhard Raabe ◽  
Dieter Enders
Keyword(s):  
Asymmetric Synthesis ◽  
One Pot

One-Pot Asymmetric Synthesis of β-Cyanohydroxymethyl α-Amino Acid Derivatives:  Formation of Three Contiguous Stereogenic Centers

2002 ◽  
Vol 4 (25) ◽  
pp. 4519-4522 ◽  
Author(s):  
Shin-ichi Watanabe ◽  
Armando Córdova ◽  
Fujie Tanaka ◽  
Carlos F. Barbas
Keyword(s):  
Amino Acid ◽  
Asymmetric Synthesis ◽  
Amino Acid Derivatives ◽  
One Pot ◽  
Stereogenic Centers
Sign in / Sign up

Export Citation Format

Share Document