NMR Spectroscopy Using a Chiral Lanthanide Shift Reagent to Assess the Optical Purity of 1-Phenylethylamine

1995 ◽  
Vol 72 (10) ◽  
pp. 945 ◽  
Author(s):  
Tito Viswanathan ◽  
Alan Toland
Keyword(s):  
Nmr Spectroscopy ◽  
Optical Purity ◽  
Shift Reagent ◽  
Lanthanide Shift Reagent

Structure of micelle bound cationic peptides by NMR spectroscopy using a lanthanide shift reagent

2020 ◽  
Vol 56 (19) ◽  
pp. 2897-2900
Author(s):  
James D. Swarbrick ◽  
John A. Karas ◽  
Jian Li ◽  
Tony Velkov
Keyword(s):  
Nmr Spectroscopy ◽  
High Resolution ◽  
Bound State ◽  
Shift Reagent ◽  
Cationic Peptides ◽  
Lanthanide Shift Reagent ◽  
Noesy Spectra

[Tm(DPA)3]3− generates paramagnetic, dispersed 2D transferred NOESY spectra for high-resolution structures of cationic peptides in the LPS micelle bound state.

Enantiomeric differentiation of acyclic terpenes by13C NMR spectroscopy using a chiral lanthanide shift reagent

2005 ◽  
Vol 43 (2) ◽  
pp. 176-179 ◽  
Author(s):  
Marie-C�cile Blanc ◽  
Pascale Bradesi ◽  
Joseph Casanova
Keyword(s):  
Nmr Spectroscopy ◽  
Shift Reagent ◽  
Lanthanide Shift Reagent

Lanthanide Induced Enhancement of Enantiomeric Shifts in Chiral Solvents and its Use in the Determination of Optical Purity

1973 ◽  
Vol 51 (22) ◽  
pp. 3726-3732 ◽  
Author(s):  
C. P. R. Jennison ◽  
Donald Mackay
Keyword(s):  
Chemical Shift ◽  
Fractional Crystallization ◽  
Sulfonic Acid ◽  
Optical Purity ◽  
Shift Reagent ◽  
Lanthanide Shift Reagent ◽  
Chemical Shift Difference ◽  
Chiral Shift Reagent ◽  
Simple Molecules

The chemical shift difference (Δv) between corresponding groups in enantiomers in the presence of both a chiral solvent ((−)-2,2,2-trifluorophenylethanol or (+)-1-phenylethylamine) and an achiral lanthanide shift reagent (Eu(dpm)3 or Eu(fod)3) is much greater than in the chiral solvent alone. In general, for simple molecules having one coordination site the Δv was smaller than that obtained with the chiral shift reagent Eu(HFC)3. Comparable values of Δv, however, were obtained with the 1,3,4-oxadiazine derivatives 4a and b, and 5, suggesting that the "chiral solvate shift system" is best suited to differentiating more complex enantiomers having several coordination sites.The shift system was used to determine the optical purity of two partially resolved substances. One of these was the (+)-oxadiazine 4a, produced in the asymmetric isomerization of the bridged pyridazine 3a by (+)-camphor-10-sulfonic acid, and optically enriched by only one fractional crystallization. The enantiomeric enrichment in the isomerization was 4.21 ± 0.08%.

Europium (S,S)-ethylenediamine-N,N'-disuccinate as a chiral lanthanide shift reagent for aqueous solutions

1991 ◽  
Vol 56 (4) ◽  
pp. 1412-1415 ◽  
Author(s):  
Junji Kido ◽  
Yoshiyuki Okamoto ◽  
Harry G. Brittain
Keyword(s):  
Aqueous Solutions ◽  
Shift Reagent ◽  
Lanthanide Shift Reagent

Conformational study of 3-substituted thietane 1-oxides. Lanthanide shift reagent approach

1979 ◽  
Vol 44 (26) ◽  
pp. 4757-4761 ◽  
Author(s):  
David J. H. Smith ◽  
John D. Finlay ◽  
C. Richard Hall ◽  
J. J. Uebel
Keyword(s):  
Shift Reagent ◽  
Lanthanide Shift Reagent ◽  
Conformational Study
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