Distances obtained from nuclear magnetic resonance nuclear Overhauser effect and relaxation time. Measurements in organic structure determination. Distances involving internally rotating methyl groups. Application to cis- and trans-crotonaldehyde

1974 ◽  
Vol 96 (15) ◽  
pp. 4773-4780 ◽  
Author(s):  
R. Rowan ◽  
J. A. McCammon ◽  
B. D. Sykes
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Relaxation Time ◽  
Magnetic Resonance ◽  
Structure Determination ◽  
Nuclear Overhauser Effect ◽  
Methyl Groups ◽  
Organic Structure ◽  
Overhauser Effect ◽  
Nuclear Overhauser ◽  
Cis And Trans

scholarly journals Conformations of 3-Deazaadenosine, 3-Deaza-8-azaadenosine, and Benzimidazole-1-β-ᴅ-riboside in Solution: HRNMR-, Proton-Relaxation-Time-, and Nuclear-Overhauser- Effect Studies

1978 ◽  
Vol 33 (5-6) ◽  
pp. 305-316 ◽  
Author(s):  
H.-D. Lüdemann ◽  
H. Pladi ◽  
E. Westhof ◽  
L. B. Townsend
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Relaxation Time ◽  
Magnetic Resonance ◽  
Nuclear Overhauser Effect ◽  
Proton Relaxation ◽  
Proton Relaxation Time ◽  
Nuclear Overhauser Enhancement ◽  
Overhauser Effect ◽  
Nuclear Overhauser ◽  
Ribose Moiety

The solution conformations of 3-deazaadenosine, 3-deaza-8-azaadenosine, and benzimidazole-1-β- ᴅ-riboside have been determined by nuclear magnetic resonance methods in aqueous and ammonia solutions. The two-state S ⇄ N model of Altona and Sundaralingam is used to analyse the ribose moiety. In order to characterize the orientation of the base relative to the ribose, longitudinal proton relaxation time and nuclear Overhauser enhancement measurements have been carried out. It is shown that 3-deazaadenosine and benzimidazole-1-β-ᴅ-riboside exist preferentially in the S- syn-g+/t (70%) and the N-anti-g+/t (30%) conformation families. In the case of 3-deaza-8-aza- adenosine, some destabilization of the g+rotamer occurs. In this case, the pulsed methods seem to indicate a preference of the base for the anti range.

Transferred Nuclear Overhauser Effect in Nuclear Magnetic Resonance Diffusion Measurements of Ligand−Protein Binding

2003 ◽  
Vol 75 (3) ◽  
pp. 627-634 ◽  
Author(s):  
Laura H. Lucas ◽  
Jiangli Yan ◽  
Cynthia K. Larive ◽  
Edward R. Zartler ◽  
Michael J. Shapiro
Keyword(s):  
Nuclear Magnetic Resonance ◽  
Magnetic Resonance ◽  
Protein Binding ◽  
Nuclear Overhauser Effect ◽  
Overhauser Effect ◽  
Nuclear Overhauser ◽  
Nuclear Magnetic
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