scholarly journals Reaction ofcis-3-Chloroacrylic Acid Dehalogenase with an Allene Substrate, 2,3-Butadienoate: Hydration via an Enamine

2011 ◽  
Vol 134 (1) ◽  
pp. 293-304 ◽  
Author(s):  
Gottfried K. Schroeder ◽  
William H. Johnson ◽  
Jamison P. Huddleston ◽  
Hector Serrano ◽  
Kenneth A. Johnson ◽  
...  
Keyword(s):  
Chloroacrylic Acid Dehalogenase

scholarly journals A Mutational Analysis of the Active Site Loop Residues incis-3-Chloroacrylic Acid Dehalogenase

Biochemistry ◽  
2013 ◽  
Vol 52 (24) ◽  
pp. 4204-4216 ◽  
Author(s):  
Gottfried K. Schroeder ◽  
Jamison P. Huddleston ◽  
William H. Johnson ◽  
Christian P. Whitman
Keyword(s):  
Active Site ◽  
Mutational Analysis ◽  
Chloroacrylic Acid Dehalogenase

The Roles of Active-Site Residues in the Catalytic Mechanism oftrans-3-Chloroacrylic Acid Dehalogenase:  A Kinetic, NMR, and Mutational Analysis†

Biochemistry ◽  
2004 ◽  
Vol 43 (14) ◽  
pp. 4082-4091 ◽  
Author(s):  
Hugo F. Azurmendi ◽  
Susan C. Wang ◽  
Michael A. Massiah ◽  
Gerrit J. Poelarends ◽  
Christian P. Whitman ◽  
...  
Keyword(s):  
Active Site ◽  
Catalytic Mechanism ◽  
Mutational Analysis ◽  
Active Site Residues ◽  
Chloroacrylic Acid Dehalogenase

Cloning, Expression, and Characterization of acis-3-Chloroacrylic Acid Dehalogenase:  Insights into the Mechanistic, Structural, and Evolutionary Relationship between Isomer-Specific 3-Chloroacrylic Acid Dehalogenases†

Biochemistry ◽  
2004 ◽  
Vol 43 (3) ◽  
pp. 759-772 ◽  
Author(s):  
Gerrit J. Poelarends ◽  
Hector Serrano ◽  
Maria D. Person ◽  
William H. Johnson, ◽  
Alexey G. Murzin ◽  
...  
Keyword(s):  
Evolutionary Relationship ◽  
Chloroacrylic Acid Dehalogenase

scholarly journals Reaction Mechanism ofcis-3-Chloroacrylic Acid Dehalogenase: A Theoretical Study

Biochemistry ◽  
2009 ◽  
Vol 48 (40) ◽  
pp. 9641-9649 ◽  
Author(s):  
Robin Sevastik ◽  
Christian P. Whitman ◽  
Fahmi Himo
Keyword(s):  
Reaction Mechanism ◽  
Theoretical Study ◽  
Chloroacrylic Acid Dehalogenase

Reactions oftrans-3-Chloroacrylic Acid Dehalogenase with Acetylene Substrates:  Consequences of and Evidence for a Hydration Reaction†

Biochemistry ◽  
2003 ◽  
Vol 42 (29) ◽  
pp. 8762-8773 ◽  
Author(s):  
Susan C. Wang ◽  
Maria D. Person ◽  
William H. Johnson, ◽  
Christian P. Whitman
Keyword(s):  
Hydration Reaction ◽  
Chloroacrylic Acid Dehalogenase

scholarly journals Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase: Implications for the catalytic and inactivation mechanisms

2011 ◽  
Vol 39 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Youzhong Guo ◽  
Hector Serrano ◽  
William H. Johnson ◽  
Stephen Ernst ◽  
Marvin L. Hackert ◽  
...  
Keyword(s):  
Crystal Structures ◽  
Chloroacrylic Acid Dehalogenase

scholarly journals Crystal Structures of Native and Inactivatedcis-3-Chloroacrylic Acid Dehalogenase

2006 ◽  
Vol 282 (4) ◽  
pp. 2440-2449 ◽  
Author(s):  
René M. de Jong ◽  
Paola Bazzacco ◽  
Gerrit J. Poelarends ◽  
William H. Johnson ◽  
Yoon Jae Kim ◽  
...  
Keyword(s):  
Crystal Structures ◽  
Chloroacrylic Acid Dehalogenase

scholarly journals A Pre-Steady State Kinetic Analysis of the αY60W Mutant oftrans-3-Chloroacrylic Acid Dehalogenase: Implications for the Mechanism of the Wild-Type Enzyme

Biochemistry ◽  
2012 ◽  
Vol 51 (46) ◽  
pp. 9420-9435 ◽  
Author(s):  
Jamison P. Huddleston ◽  
Gottfried K. Schroeder ◽  
Kenneth A. Johnson ◽  
Christian P. Whitman
Keyword(s):  
Steady State ◽  
Kinetic Analysis ◽  
Wild Type ◽  
Wild Type Enzyme ◽  
Steady State Kinetic ◽  
Chloroacrylic Acid Dehalogenase ◽  
State Kinetic

scholarly journals Flexibility in active site ofcis-3-chloroacrylic acid dehalogenase revealed by multiple structures

2008 ◽  
Vol 64 (a1) ◽  
pp. C278-C279
Author(s):  
M.L. Hackert ◽  
S.R. Ernst ◽  
Y. Guo ◽  
H. Serrano ◽  
W.H. Johnson ◽  
...  
Keyword(s):  
Active Site ◽  
Multiple Structures ◽  
Chloroacrylic Acid Dehalogenase

Stereospecific Alkylation ofcis-3-Chloroacrylic Acid Dehalogenase by (R)-Oxirane-2-carboxylate:  Analysis and Mechanistic Implications†

Biochemistry ◽  
2004 ◽  
Vol 43 (22) ◽  
pp. 7187-7196 ◽  
Author(s):  
Gerrit J. Poelarends ◽  
Hector Serrano ◽  
William H. Johnson ◽  
Christian P. Whitman
Keyword(s):  
Chloroacrylic Acid Dehalogenase
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