Modular Pathway Engineering of Diterpenoid Synthases and the Mevalonic Acid Pathway for Miltiradiene Production

2012 ◽  
Vol 134 (6) ◽  
pp. 3234-3241 ◽  
Author(s):  
Yongjin J. Zhou ◽  
Wei Gao ◽  
Qixian Rong ◽  
Guojie Jin ◽  
Huiying Chu ◽  
...  
Keyword(s):  
Mevalonic Acid ◽  
Pathway Engineering ◽  
Mevalonic Acid Pathway ◽  
Acid Pathway

scholarly journals Microbial biotransformation as a tool for drug development based on natural products from mevalonic acid pathway: A review

2015 ◽  
Vol 6 (1) ◽  
pp. 17-33 ◽  
Author(s):  
Mohamed-Elamir F. Hegazy ◽  
Tarik A. Mohamed ◽  
Abdelsamed I. ElShamy ◽  
Abou-El-Hamd H. Mohamed ◽  
Usama A. Mahalel ◽  
...  
Keyword(s):  
Natural Products ◽  
Drug Development ◽  
Mevalonic Acid ◽  
Mevalonic Acid Pathway ◽  
Acid Pathway

scholarly journals Peroxisomal Localization of Arabidopsis Isopentenyl Diphosphate Isomerases Suggests That Part of the Plant Isoprenoid Mevalonic Acid Pathway Is Compartmentalized to Peroxisomes

2008 ◽  
Vol 148 (3) ◽  
pp. 1219-1228 ◽  
Author(s):  
Maya Sapir-Mir ◽  
Anahit Mett ◽  
Eduard Belausov ◽  
Shira Tal-Meshulam ◽  
Ahuva Frydman ◽  
...  
Keyword(s):  
Mevalonic Acid ◽  
Isopentenyl Diphosphate ◽  
Mevalonic Acid Pathway ◽  
Acid Pathway

Procedures for the Isolation and Quantification of the Intermediates of the Mevalonic Acid Pathway

1993 ◽  
Vol 215 (1) ◽  
pp. 142-149 ◽  
Author(s):  
D. Mccaskill ◽  
R. Croteau
Keyword(s):  
Mevalonic Acid ◽  
Mevalonic Acid Pathway ◽  
Acid Pathway

Genetic Studies into Musty Odor Production by Actinomycetes

1992 ◽  
Vol 25 (2) ◽  
pp. 171-176 ◽  
Author(s):  
Y. Ishibashi
Keyword(s):  
Mevalonic Acid ◽  
Aerial Mycelium ◽  
Pigment Formation ◽  
Genetic Studies ◽  
Phenotypic Characters ◽  
Taste And Odor ◽  
Mevalonic Acid Pathway ◽  
Musty Odor ◽  
Acid Pathway ◽  
Odor Production

Musty taste and odor is a serious problem for drinking water. Much data regarding its occurrence are being accumulated. However, we may be able to solve this problem by inquiring into the nature of secondary metabolism through the mevalonic acid pathway in actinomycetes and/or cyanobacteria that yield musty smelling compounds. Therefore, genetic analysis is applied to look for new solutions. By investigating Streptomyces sp. with the protocol to recover plasmid DNA, it was difficult to get the infinitesimally small covalently closed circular (ccc) plasmid. On the other hand, Streptomyces strains which have been cured, which implicates plasmids, lost phenotypic characters such as musty odor production with aerial mycelium and pigment formation. DNA in Streptomyces are unstable and often cause amplification and deletion. The existence of giant linear plasmids was detected in musty smelling strains using pulsed – field gel electrophoresis.

scholarly journals The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer

2018 ◽  
Vol 20 (1) ◽  
Author(s):  
Anjana Bhardwaj ◽  
Harpreet Singh ◽  
Celestine Marie Trinidad ◽  
Constance T. Albarracin ◽  
Kelly K. Hunt ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Mevalonic Acid ◽  
Potential Target ◽  
Mevalonic Acid Pathway ◽  
Acid Pathway

Biochemistry of the Mevalonic Acid Pathway to Terpenoids

1991 ◽  
Vol 19 (7) ◽  
pp. 611
Author(s):  
Peter G. Waterman
Keyword(s):  
Mevalonic Acid ◽  
Mevalonic Acid Pathway ◽  
Acid Pathway

The regulation of activity of main mevalonic acid pathway enzymes

2000 ◽  
Vol 28 (5) ◽  
pp. A333-A333
Author(s):  
A. Szkopinska ◽  
F. Karst
Keyword(s):  
Mevalonic Acid ◽  
Mevalonic Acid Pathway ◽  
Regulation Of Activity ◽  
Acid Pathway
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