Structure–Reactivity Effects on Intrinsic Primary Kinetic Isotope Effects for Hydride Transfer Catalyzed by Glycerol-3-phosphate Dehydrogenase

Archie C. Reyes; Tina L. Amyes; John P. Richard

doi:10.1021/jacs.6b07028

Structure–Reactivity Effects on Intrinsic Primary Kinetic Isotope Effects for Hydride Transfer Catalyzed by Glycerol-3-phosphate Dehydrogenase

Journal of the American Chemical Society ◽

10.1021/jacs.6b07028 ◽

2016 ◽

Vol 138 (44) ◽

pp. 14526-14529 ◽

Cited By ~ 7

Author(s):

Archie C. Reyes ◽

Tina L. Amyes ◽

John P. Richard

Keyword(s):

Isotope Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Kinetic Isotope ◽

Glycerol 3 Phosphate Dehydrogenase

Download Full-text

Primary Deuterium Kinetic Isotope Effects: A Probe for the Origin of the Rate Acceleration for Hydride Transfer Catalyzed by Glycerol-3-Phosphate Dehydrogenase

Biochemistry ◽

10.1021/acs.biochem.8b00536 ◽

2018 ◽

Vol 57 (29) ◽

pp. 4338-4348 ◽

Cited By ~ 3

Author(s):

Archie C. Reyes ◽

Tina L. Amyes ◽

John P. Richard

Keyword(s):

Isotope Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Kinetic Isotope ◽

Rate Acceleration ◽

Glycerol 3 Phosphate Dehydrogenase

Download Full-text

Substituent Effects on Temperature Dependence of Kinetic Isotope Effects in Hydride-Transfer Reactions of NADH/NAD+ Analogues in Solution: Reaction Center Rigidity Is the Key

Organic Letters ◽

10.1021/acs.orglett.0c02049 ◽

2020 ◽

Vol 22 (15) ◽

pp. 5963-5967

Author(s):

Peter Maness ◽

Shailendra Koirala ◽

Pratichhya Adhikari ◽

Nasim Salimraftar ◽

Yun Lu

Keyword(s):

Temperature Dependence ◽

Reaction Center ◽

Isotope Effects ◽

Substituent Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Transfer Reactions ◽

Kinetic Isotope ◽

Solution Reaction ◽

Hydride Transfer Reactions

Download Full-text

Hydride Transfer in DHFR by Transition Path Sampling, Kinetic Isotope Effects, and Heavy Enzyme Studies

Biochemistry ◽

10.1021/acs.biochem.5b01241 ◽

2015 ◽

Vol 55 (1) ◽

pp. 157-166 ◽

Cited By ~ 22

Author(s):

Zhen Wang ◽

Dimitri Antoniou ◽

Steven D. Schwartz ◽

Vern L. Schramm

Keyword(s):

Isotope Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Path Sampling ◽

Transition Path ◽

Transition Path Sampling ◽

Kinetic Isotope

Download Full-text

Primary kinetic isotope effects in hydride transfer: experimental studies of intramolecular hydride migration and ab initio molecular orbital calculations of model systems

Journal of the Chemical Society Perkin Transactions 2 ◽

10.1039/p29880001345 ◽

1988 ◽

pp. 1345 ◽

Cited By ~ 6

Author(s):

Ian H. Hillier ◽

Stephen Smith ◽

Stephen C. Mason ◽

Stephen N. Whittleton ◽

C. Ian F. Watt ◽

...

Keyword(s):

Ab Initio ◽

Molecular Orbital ◽

Isotope Effects ◽

Experimental Studies ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Model Systems ◽

Molecular Orbital Calculations ◽

Kinetic Isotope

Download Full-text

Steric Effects on the Primary Isotope Dependence of Secondary Kinetic Isotope Effects in Hydride Transfer Reactions in Solution: Caused by the Isotopically Different Tunneling Ready State Conformations?

Journal of the American Chemical Society ◽

10.1021/jacs.5b03085 ◽

2015 ◽

Vol 137 (20) ◽

pp. 6653-6661 ◽

Cited By ~ 11

Author(s):

Binita Maharjan ◽

Mahdi Raghibi Boroujeni ◽

Jonathan Lefton ◽

Ormacinda R. White ◽

Mortezaali Razzaghi ◽

...

Keyword(s):

Isotope Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Transfer Reactions ◽

Steric Effects ◽

Kinetic Isotope ◽

Hydride Transfer Reactions

Download Full-text

ChemInform Abstract: Primary Kinetic Isotope Effects in Hydride Transfer: Experimental Studies of Intramolecular Hydride Migration and ab initio MO Calculations of Model Systems.

ChemInform ◽

10.1002/chin.198844052 ◽

1988 ◽

Vol 19 (44) ◽

Author(s):

I. H. HILLIER ◽

S. SMITH ◽

S. C. MASON ◽

S. N. WHITTLETON ◽

C. I. F. WATT ◽

...

Keyword(s):

Ab Initio ◽

Isotope Effects ◽

Experimental Studies ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Model Systems ◽

Mo Calculations ◽

Kinetic Isotope ◽

Ab Initio Mo Calculations ◽

Ab Initio Mo

Download Full-text

Theoretical kinetic isotope effects for the hydride-transfer step in lactate dehydrogenase

Journal of the Chemical Society Faraday Transactions ◽

10.1039/ft9949001703 ◽

1994 ◽

Vol 90 (12) ◽

pp. 1703-1707 ◽

Cited By ~ 25

Author(s):

J. Andrés ◽

V. Moliner ◽

V. S. Safont

Keyword(s):

Lactate Dehydrogenase ◽

Isotope Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Kinetic Isotope ◽

Transfer Step

Download Full-text

Solvent effects on the temperature dependence of the primary kinetic isotope effects for hydride transfer reactions in solution

10.1021/scimeetings.0c05537 ◽

2020 ◽

Author(s):

Pratichhya Adhikari ◽

Shailendra Koirala

Keyword(s):

Temperature Dependence ◽

Solvent Effects ◽

Isotope Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Transfer Reactions ◽

Kinetic Isotope ◽

Hydride Transfer Reactions

Download Full-text

Theoretical kinetic isotope effects for the hydride transfer from formate to carbon dioxide: A comparison of theory with experiment

Journal of Computational Chemistry ◽

10.1002/jcc.540120912 ◽

1991 ◽

Vol 12 (9) ◽

pp. 1134-1141 ◽

Cited By ~ 7

Author(s):

Jeffrey P. Jones ◽

Jeffrey L. Urbauer

Keyword(s):

Carbon Dioxide ◽

Isotope Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Kinetic Isotope

Download Full-text

Primary Kinetic Isotope Effects on Hydride Transfer from 1,3-Dimethyl-2-phenylbenzimidazoline to NAD+Analogues [J. Am. Chem. Soc.2001,123, 7492−7496].

Journal of the American Chemical Society ◽

10.1021/ja0151302 ◽

2002 ◽

Vol 124 (22) ◽

pp. 6502-6502 ◽

Cited By ~ 1

Author(s):

In-Sook Han Lee ◽

Eun Hee Jeoung ◽

Maurice M. Kreevoy

Keyword(s):

Isotope Effects ◽

Hydride Transfer ◽

Kinetic Isotope Effects ◽

Kinetic Isotope

Download Full-text