Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A2A Adenosine Receptor

Faculty Opinions recommendation of Allosteric coupling of drug binding and intracellular signaling in the A2A adenosine receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732378223.793542005 ◽

2018 ◽

Author(s):

Wolfgang Jahnke

Keyword(s):

Adenosine Receptor ◽

Intracellular Signaling ◽

Drug Binding ◽

A2a Adenosine Receptor ◽

Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor

Cell ◽

10.1016/j.cell.2017.12.004 ◽

2018 ◽

Vol 172 (1-2) ◽

pp. 68-80.e12 ◽

Cited By ~ 87

Author(s):

Matthew T. Eddy ◽

Ming-Yue Lee ◽

Zhan-Guo Gao ◽

Kate L. White ◽

Tatiana Didenko ◽

...

Keyword(s):

Adenosine Receptor ◽

Intracellular Signaling ◽

Drug Binding ◽

A2a Adenosine Receptor ◽

Allosteric Coupling of Drug Binding and Intracellular Signaling in the A2A Adenosine Receptor

NMR with Biological Macromolecules in Solution ◽

10.1142/9789811235795_0023 ◽

2021 ◽

pp. 184-196

Author(s):

Matthew T. Eddy ◽

Ming-Yue Lee ◽

Zhan-Guo Gao ◽

Kate L. White ◽

Tatiana Didenko ◽

...

Keyword(s):

Adenosine Receptor ◽

Intracellular Signaling ◽

Drug Binding ◽

A2a Adenosine Receptor ◽

Faculty Opinions recommendation of The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1123146.596177 ◽

2009 ◽

Author(s):

Hao Wu ◽

Yu-Chih Lo

Keyword(s):

Crystal Structure ◽

Adenosine Receptor ◽

Faculty Opinions recommendation of Structure of an agonist-bound human A2A adenosine receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.9752956.10443054 ◽

2011 ◽

Author(s):

Manoj Desai ◽

Britton Corkey

Keyword(s):

Adenosine Receptor ◽

Ligand-Based Virtual Screening Using Tailored Ensembles: A Prioritization Tool for Dual A2A Adenosine Receptor Antagonists / Monoamine Oxidase B Inhibitors

Current Pharmaceutical Design ◽

10.2174/1381612822666160302103542 ◽

2016 ◽

Vol 22 (21) ◽

pp. 3082-3096 ◽

Cited By ~ 7

Author(s):

Aliuska Morales Helguera ◽

Yunierkis Perez-Castillo ◽

M. Natália D.S. Cordeiro ◽

Eduardo Tejera ◽

César Paz-y-Miño ◽

...

Keyword(s):

Virtual Screening ◽

Monoamine Oxidase ◽

Adenosine Receptor ◽

Monoamine Oxidase B ◽

Receptor Antagonists ◽

A2A Adenosine Receptor Antagonists as Therapeutic Candidates: Are They Still an Interesting Challenge?

Mini-Reviews in Medicinal Chemistry ◽

10.2174/1389557518666180423113051 ◽

2018 ◽

Vol 18 (14) ◽

pp. 1168-1174 ◽

Cited By ~ 8

Author(s):

Barbara Cacciari ◽

Giampiero Spalluto ◽

Stephanie Federico

Keyword(s):

Adenosine Receptor ◽

Receptor Antagonists ◽

Enhanced protection from renal ischemia: Reperfusion injury with A2A-adenosine receptor activation and PDE 4 inhibition

Kidney International ◽

10.1046/j.1523-1755.2001.0590062114.x ◽

2001 ◽

Vol 59 (6) ◽

pp. 2114 ◽

Cited By ~ 2

Author(s):

Mark D. Okusa ◽

Joel Linden ◽

Liping Huang ◽

Diane L. Rosin ◽

David F. Smith ◽

...

Keyword(s):

Reperfusion Injury ◽

Adenosine Receptor ◽

Ischemia Reperfusion Injury ◽

Ischemia Reperfusion ◽

Receptor Activation ◽

Renal Ischemia ◽

A2a Adenosine Receptor ◽

Renal Ischemia Reperfusion Injury ◽

Adenosine Receptor Activation

Constitutive activity of the A2A adenosine receptor and compartmentalised cyclic AMP signalling fine-tune noradrenaline release

Purinergic Signalling ◽

10.1007/s11302-012-9298-3 ◽

2012 ◽

Vol 8 (4) ◽

pp. 677-692 ◽

Cited By ~ 7

Author(s):

Edin Ibrisimovic ◽

Helmut Drobny ◽

Qiong Yang ◽

Thomas Höfer ◽

Stefan Boehm ◽

...

Keyword(s):

Cyclic Amp ◽

Noradrenaline Release ◽

Adenosine Receptor ◽

Constitutive Activity ◽

A2a Adenosine Receptor ◽

Fine Tune

Association study of A2a adenosine receptor genetic polymorphism in panic disorder

Neuroscience Letters ◽

10.1016/j.neulet.2004.12.012 ◽

2005 ◽

Vol 378 (2) ◽

pp. 98-101 ◽

Cited By ~ 42

Author(s):

Pok Lam ◽

Chen-Jee Hong ◽

Shih-Jen Tsai

Keyword(s):

Genetic Polymorphism ◽

Panic Disorder ◽

Association Study ◽

Adenosine Receptor ◽