Anti-inflammatory Activities of an Ethanol Extract ofEcklonia stoloniferain Lipopolysaccharide-Stimulated RAW 264.7 Murine Macrophage Cells

2012 ◽  
Vol 60 (36) ◽  
pp. 9120-9129 ◽  
Author(s):  
Min-Sup Lee ◽  
Mi-Sung Kwon ◽  
Ji-Woong Choi ◽  
Taisun Shin ◽  
Hong Kyoon No ◽  
...  
Keyword(s):  
Ethanol Extract ◽  
Raw 264.7 ◽  
Murine Macrophage ◽  
Macrophage Cells ◽  
Anti Inflammatory

scholarly journals Anti-Inflammatory Effects of Aurantiochytrium limacinum 4W-1b Ethanol Extract on Murine Macrophage RAW264 Cells

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Shinya Takahashi ◽  
Masaki Yoshida ◽  
Makoto M. Watanabe ◽  
Hiroko Isoda
Keyword(s):  
Proinflammatory Cytokine ◽  
Tumor Necrosis ◽  
Inflammatory Responses ◽  
Ethanol Extract ◽  
No Production ◽  
Murine Macrophage ◽  
Macrophage Cells ◽  
Anti Inflammatory ◽  
Ethanol Extracts ◽  
Necrosis Factor

Aurantiochytrium limacinum 4W-1b (AL4W-1b) is a newly discovered microalgal strain with unique features. In the present study, we investigated the effects of ethanol extracts of AL4W-1b on lipopolysaccharide- (LPS-) induced inflammatory responses in RAW264 murine macrophage cells. Pretreatment of RAW264 cells with the AL4W-1b extract significantly reduced the production of LPS-induced nitric oxide (NO) and the expression of proinflammatory cytokine genes, including tumor necrosis factor α, interleukin- (IL-) 1β, and IL-6. Treatment with the AL4W-1b extract also decreased the production of IL-1β and IL-6. These results suggest that AL4W-1b might have anti-inflammatory effects in RAW264 cells. The NF-κB inhibitor, BAY 11-7082, synergistically prevented LPS-induced NO production after pretreatment with the AL4W-1b extract. Thus, the AL4W-1b extract may affect not only the NF-κB pathway but also other inflammatory pathways. To the best of our knowledge, this is the first study to report the anti-inflammatory effects of AL4W-1b extract and its mechanism of action in LPS-stimulated murine macrophage cells.

Anti-Inflammatory Effect of Ginsenoside Rh2-Mix on Lipopolysaccharide-Stimulated RAW 264.7 Murine Macrophage Cells

2018 ◽  
Vol 21 (10) ◽  
pp. 951-960 ◽  
Author(s):  
Delgerzul Baatar ◽  
Muhammad Zubair Siddiqi ◽  
Wan Taek Im ◽  
Nisar Ul Khaliq ◽  
Seong Gu Hwang
Keyword(s):  
Raw 264.7 ◽  
Murine Macrophage ◽  
Ginsenoside Rh2 ◽  
Macrophage Cells ◽  
Anti Inflammatory ◽  
Inflammatory Effect
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