Derivatives of (+)(-) limonene. Effect of chain length in n-alkyl quaternary ammonium derivatives on plant growth retardant activity

1968 ◽  
Vol 16 (3) ◽  
pp. 523-524 ◽  
Author(s):  
A. P. Pieringer ◽  
W. F. Newhall
Keyword(s):  
Plant Growth ◽  
Chain Length ◽  
Quaternary Ammonium ◽  
Growth Retardant ◽  
Derivatives Of

Isomerism in Quaternary Ammonium Derivatives of (+)-Limonene and Its Effect on Plant Growth

1969 ◽  
Vol 17 (1) ◽  
pp. 153-155
Author(s):  
William Newhall ◽  
A Pieringer
Keyword(s):  
Plant Growth ◽  
Quaternary Ammonium ◽  
Derivatives Of

scholarly journals Syntheses and Plant Growth Retardant Activities of Quaternary Ammonium Compounds Derived from α-Ionone and Isophorone

1974 ◽  
Vol 38 (2) ◽  
pp. 417-422 ◽  
Author(s):  
Hisae HARUTA ◽  
Hideo YAGI ◽  
Takashi IWATA ◽  
Saburo TAMURA
Keyword(s):  
Plant Growth ◽  
Quaternary Ammonium ◽  
Quaternary Ammonium Compounds ◽  
Growth Retardant ◽  
Ammonium Compounds

Correlation of Pseudocholinesterase Inhibition and Plant Growth Retardation by Quaternary Ammonium Derivatives of (+)-Limonene

Nature ◽  
1969 ◽  
Vol 223 (5209) ◽  
pp. 965-966 ◽  
Author(s):  
WILLIAM F. NEWHALL
Keyword(s):  
Plant Growth ◽  
Growth Retardation ◽  
Quaternary Ammonium ◽  
Derivatives Of

Syntheses and Plant Growth Retardant Activities of Quaternary Ammonium Compounds Derived from α-Ionone and Isophorone

1974 ◽  
Vol 38 (2) ◽  
pp. 417-422 ◽  
Author(s):  
Hisae Haruta ◽  
Hideo Yagi ◽  
Takashi Iwata ◽  
Saburo Tamura
Keyword(s):  
Plant Growth ◽  
Quaternary Ammonium ◽  
Quaternary Ammonium Compounds ◽  
Growth Retardant ◽  
Ammonium Compounds

1010. Stereoisomeric pairs of cyclic quaternary ammonium salts. Part V. Derivatives of 4-aza-5α-cholestane

1965 ◽  
Vol 0 (0) ◽  
pp. 5439-5446 ◽  
Author(s):  
James McKenna ◽  
Jean M. McKenna ◽  
A. Tulley
Keyword(s):  
Quaternary Ammonium ◽  
Quaternary Ammonium Salts ◽  
Ammonium Salts ◽  
Derivatives Of

scholarly journals Discovery, characterization and functional improvement of kumamonamide as a novel plant growth inhibitor that disturbs plant microtubules

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Takashi Ishida ◽  
Haruna Yoshimura ◽  
Masatsugu Takekawa ◽  
Takumi Higaki ◽  
Takashi Ideue ◽  
...  
Keyword(s):  
Plant Growth ◽  
Human Life ◽  
Growth Inhibitor ◽  
Herbicidal Activity ◽  
Functional Improvement ◽  
Microtubule Inhibitors ◽  
Plant Microtubules ◽  
Plant Growth Inhibitor ◽  
Derivatives Of ◽  
Synthetic Intermediate

AbstractThe discovery and useful application of natural products can help improve human life. Chemicals that inhibit plant growth are broadly utilized as herbicides to control weeds. As various types of herbicides are required, the identification of compounds with novel modes of action is desirable. In the present study, we discovered a novelN-alkoxypyrrole compound, kumamonamide fromStreptomyces werraensisMK493-CF1 and established a total synthesis procedure. Resulted in the bioactivity assays, we found that kumamonamic acid, a synthetic intermediate of kumamonamide, is a potential plant growth inhibitor. Further, we developed various derivatives of kumamonamic acid, including a kumamonamic acid nonyloxy derivative (KAND), which displayed high herbicidal activity without adverse effects on HeLa cell growth. We also detected that kumamonamic acid derivatives disturb plant microtubules; and additionally, that KAND affected actin filaments and induced cell death. These multifaceted effects differ from those of known microtubule inhibitors, suggesting a novel mode of action of kumamonamic acid, which represents an important lead for the development of new herbicides.

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