2-Substituted Penems with Amino Acid-Related Side Chains: Synthesis and Antibacterial Activity of a New Series of .beta.-Lactam Antibiotics

1995 ◽  
Vol 38 (21) ◽  
pp. 4244-4256 ◽  
Author(s):  
Maria Altamura ◽  
Enzo Perrotta ◽  
Piero Sbraci ◽  
Vittorio Pestellini ◽  
Federico Arcamone ◽  
...  
1991 ◽  
Vol 44 (8) ◽  
pp. 844-853 ◽  
Author(s):  
BERNARD PIROTTE ◽  
JACQUES DELARGE ◽  
JACQUES COYETTE ◽  
JEAN-MARIE FRERE

1985 ◽  
Vol 38 (11) ◽  
pp. 1536-1549 ◽  
Author(s):  
CHOSAKU YOSHIDA ◽  
TAKAKO HORI ◽  
KAISHU MOMONOI ◽  
KATSUYUKI NAGUMO ◽  
JOJI NAKANO ◽  
...  

1976 ◽  
Vol 19 (2) ◽  
pp. 330-333 ◽  
Author(s):  
M. L. Edwards ◽  
R. E. Bambury ◽  
H. W. Ritter

1981 ◽  
Vol 29 (7) ◽  
pp. 1986-1997 ◽  
Author(s):  
TERUO MURAKAMI ◽  
HIROMU TAMAUCHI ◽  
MASARU YAMAZAKI ◽  
KAZUYOSHI KUBO ◽  
AKIRA KAMADA ◽  
...  

1986 ◽  
Vol 39 (2) ◽  
pp. 230-241 ◽  
Author(s):  
NOBUHIRO OHI ◽  
BUNYA AOKI ◽  
TEIZO SHINOZAKI ◽  
KANZI MORO ◽  
TAKAO NOTO ◽  
...  

2014 ◽  
Vol 27 (6) ◽  
pp. 530-544 ◽  
Author(s):  
Adrienne T. Terico ◽  
Jason C. Gallagher

Penicillin is the most frequently reported cause of drug allergy, and cross-reactivity of penicillins with other beta-lactam antibiotics is an area of debate. This review evaluates the available data on immunoglobulin E-mediated penicillin hypersensitivity and cross-reactivity with cephalosporin, carbapenem, and monobactam antibiotics. A MEDLINE search was conducted from 1950 to October 2013, and selected references from review articles were also evaluated. There is a wide variety in reported incidences of cross-reactivity between penicillins and cephalosporins or carbapenems, with early retrospective studies suggesting up to 41.7% and 47.4% cross-reactivity, respectively. Conversely, the use of monobactam antibiotics is frequently employed in the case of a penicillin allergy, as prescribers believe that there is no cross-reactivity between the 2 drug classes. More recent prospective studies suggest that the rates of cross-reactivity with cephalosporins and carbapenems are <5% and <1%, respectively. Similarities in penicillin and cephalosporin side chains may play a role in cross-reactivity between these classes. Cross-reactivity with monobactams is essentially negligible; however, there are some clinical data to support an interaction between ceftazidime and aztreonam, due to the similarity of their side chains. The data reviewed suggest that avoidance of other beta-lactams in patients with type 1 hypersensitivity to penicillins should be reconsidered.


Sign in / Sign up

Export Citation Format

Share Document