Antipsoriatic Anthrones with Modulated Redox Properties. 2. Novel Derivatives of Chrysarobin and Isochrysarobin-Antiproliferative Activity and 5-Lipoxygenase Inhibition

1994 ◽  
Vol 37 (11) ◽  
pp. 1660-1669 ◽  
Author(s):  
Klaus Mueller ◽  
Peter Leukel ◽  
Klaus Ziereis ◽  
Ingo Gawlik
Molecules ◽  
2021 ◽  
Vol 26 (6) ◽  
pp. 1608
Author(s):  
Stephen Lo ◽  
Euphemia Leung ◽  
Bruno Fedrizzi ◽  
David Barker

Quercetin is a flavonoid that is found in many plant materials, including commonly eaten fruits and vegetables. The compound is well known for its wide range of biological activities. In this study, 5-O-acyl derivatives of quercetin were synthesised and assessed for their antiproliferative activity against the HCT116 colon cancer and MDA-MB-231 breast cancer cell lines; and their radical scavenging activity against the 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical cation and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical species. Four derivatives were found to have improved the antiproliferative activity compared to quercetin whilst retaining radical scavenging activity.


1977 ◽  
Vol 8 (16) ◽  
pp. no-no
Author(s):  
O. S. KSENZHEK ◽  
S. A. PETROVA ◽  
S. V. OLEINIK ◽  
M. V. KOLODYAZHNYI ◽  
V. Z. MOSKOVSKII

ChemInform ◽  
2016 ◽  
Vol 47 (47) ◽  
Author(s):  
Edgars Paegle ◽  
Ilona Domracheva ◽  
Baiba Turovska ◽  
Marina Petrova ◽  
Iveta Kanepe-Lapsa ◽  
...  

2021 ◽  
Author(s):  
Alexei N. Izmest'ev ◽  
Galina A. Gazieva ◽  
Lada V. Anikina ◽  
Sergey A. Pukhov ◽  
Valentina A. Karnoukhova ◽  
...  

Two series of regioisomeric heterylmethylidene derivatives of imidazo[4,5-e]thiazolo[3,2-b]-1,2,4-triazines and imidazo[4,5-e]thiazolo[2,3-c]-1,2,4-triazines were synthesized. Several compounds exhibiting high antiproliferative activity were found.


Crystals ◽  
2017 ◽  
Vol 7 (1) ◽  
pp. 15 ◽  
Author(s):  
Monika Kadela-Tomanek ◽  
Maria Jastrzębska ◽  
Ewa Bębenek ◽  
Elwira Chrobak ◽  
Małgorzata Latocha ◽  
...  

2013 ◽  
Vol 23 (7) ◽  
pp. 2265-2267 ◽  
Author(s):  
Yanmin Huang ◽  
Jianguo Cui ◽  
Sijing Chen ◽  
Chunfang Gan ◽  
Qiucui Yao ◽  
...  

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