Chemoenzymatic Synthesis of New 2,4-syn-Functionalized (S)-Glutamate Analogues and Structure–Activity Relationship Studies at Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters

2013 ◽  
Vol 56 (4) ◽  
pp. 1614-1628 ◽  
Author(s):  
Zeinab Assaf ◽  
Anja P. Larsen ◽  
Raminta Venskutonytė ◽  
Liwei Han ◽  
Bjarke Abrahamsen ◽  
...  
Keyword(s):  
Amino Acid ◽  
Glutamate Receptors ◽  
Excitatory Amino Acid ◽  
Structure Activity Relationship ◽  
Chemoenzymatic Synthesis ◽  
Ionotropic Glutamate Receptors ◽  
Activity Relationship ◽  
Amino Acid Transporters ◽  
Structure Activity ◽  
Glutamate Analogues

4,4-Dimethyl- and Diastereomeric 4-Hydroxy-4-methyl- (2S)-Glutamate Analogues Display Distinct Pharmacological Profiles at Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters

ChemMedChem ◽  
2009 ◽  
Vol 4 (11) ◽  
pp. 1925-1929 ◽  
Author(s):  
Lennart Bunch ◽  
Darryl S. Pickering ◽  
Thierry Gefflaut ◽  
Virginie Vinatier ◽  
Virgil Helaine ◽  
...  
Keyword(s):  
Amino Acid ◽  
Glutamate Receptors ◽  
Excitatory Amino Acid ◽  
Ionotropic Glutamate Receptors ◽  
Amino Acid Transporters ◽  
Excitatory Amino Acid Transporters ◽  
Glutamate Analogues ◽  
Pharmacological Profiles

Structure–Activity Relationship Studies of Argiotoxins: Selective and Potent Inhibitors of Ionotropic Glutamate Receptors

2013 ◽  
Vol 56 (3) ◽  
pp. 1171-1181 ◽  
Author(s):  
Mette H. Poulsen ◽  
Simon Lucas ◽  
Tinna B. Bach ◽  
Anne F. Barslund ◽  
Claudius Wenzler ◽  
...  
Keyword(s):  
Glutamate Receptors ◽  
Structure Activity Relationship ◽  
Ionotropic Glutamate Receptors ◽  
Activity Relationship ◽  
Structure Activity

scholarly journals Cover Picture: Structure-Activity Relationship Study of Spider Polyamine Toxins as Inhibitors of Ionotropic Glutamate Receptors (ChemMedChem 12/2014)

ChemMedChem ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. 2605-2605
Author(s):  
Xiao-Feng Xiong ◽  
Mette H. Poulsen ◽  
Rama A. Hussein ◽  
Niels G. Nørager ◽  
Kristian Strømgaard
Keyword(s):  
Glutamate Receptors ◽  
Structure Activity Relationship ◽  
Ionotropic Glutamate Receptors ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study ◽  
Polyamine Toxins

Structure–Activity Relationship Studies of N-Methylated and N-Hydroxylated Spider Polyamine Toxins as Inhibitors of Ionotropic Glutamate Receptors

2014 ◽  
Vol 57 (11) ◽  
pp. 4940-4949 ◽  
Author(s):  
Niels G. Nørager ◽  
Mette H. Poulsen ◽  
Anna G. Jensen ◽  
Nanna S. Jeppesen ◽  
Anders S. Kristensen ◽  
...  
Keyword(s):  
Glutamate Receptors ◽  
Structure Activity Relationship ◽  
Ionotropic Glutamate Receptors ◽  
Activity Relationship ◽  
Structure Activity ◽  
Polyamine Toxins

Structure-Activity Relationship Study of Spider Polyamine Toxins as Inhibitors of Ionotropic Glutamate Receptors

ChemMedChem ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. 2661-2670 ◽  
Author(s):  
Xiao-Feng Xiong ◽  
Mette H. Poulsen ◽  
Rama A. Hussein ◽  
Niels G. Nørager ◽  
Kristian Strømgaard
Keyword(s):  
Glutamate Receptors ◽  
Structure Activity Relationship ◽  
Ionotropic Glutamate Receptors ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Study ◽  
Polyamine Toxins

scholarly journals Design and Synthesis of 2,3-trans-Proline Analogues as Ligands for Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters

2019 ◽  
Vol 10 (6) ◽  
pp. 2989-3007 ◽  
Author(s):  
Christian B. M. Poulie ◽  
Anna Alcaide ◽  
Mikkel Krell-Jørgensen ◽  
Younes Larsen ◽  
Eloi Astier ◽  
...  
Keyword(s):  
Amino Acid ◽  
Glutamate Receptors ◽  
Excitatory Amino Acid ◽  
Ionotropic Glutamate Receptors ◽  
Amino Acid Transporters ◽  
Excitatory Amino Acid Transporters ◽  
Design And Synthesis
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