scholarly journals Synthesis and Biological Evaluation of New Carbohydrate-Substituted Indenoisoquinoline Topoisomerase I Inhibitors and Improved Syntheses of the Experimental Anticancer Agents Indotecan (LMP400) and Indimitecan (LMP776)

2014 ◽  
Vol 57 (4) ◽  
pp. 1495-1512 ◽  
Author(s):  
Daniel E. Beck ◽  
Keli Agama ◽  
Christophe Marchand ◽  
Adel Chergui ◽  
Yves Pommier ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
Topoisomerase I ◽  
Biological Evaluation ◽  
Topoisomerase I Inhibitors ◽  
Synthesis And Biological Evaluation

Synthesis and Biological Evaluation of 1,5-Naphthyridines as Topoisomerase I Inhibitors. A New Family of Antiproliferative Agents

2015 ◽  
Vol 14 (23) ◽  
pp. 2722-2728 ◽  
Author(s):  
Concepcion Alonso ◽  
Maria Fuertes ◽  
Maria Gonzalez ◽  
Alicia Rodriguez-Gascon ◽  
Gloria Rubiales ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Biological Evaluation ◽  
Antiproliferative Agents ◽  
Topoisomerase I Inhibitors ◽  
New Family ◽  
Synthesis And Biological Evaluation

Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Topoisomerase I Inhibitors Featuring Polyamine Side Chains on the Lactam Nitrogen

2003 ◽  
Vol 46 (26) ◽  
pp. 5712-5724 ◽  
Author(s):  
Muthukaman Nagarajan ◽  
Xiangshu Xiao ◽  
Smitha Antony ◽  
Glenda Kohlhagen ◽  
Yves Pommier ◽  
...  
Keyword(s):  
Topoisomerase I ◽  
Biological Evaluation ◽  
Side Chains ◽  
Design Synthesis ◽  
Topoisomerase I Inhibitors ◽  
Synthesis And Biological Evaluation

scholarly journals Dibenzo[c,h][1,5]naphthyridinediones as Topoisomerase I Inhibitors: Design, Synthesis, and Biological Evaluation

2012 ◽  
Vol 77 (11) ◽  
pp. 5167-5172 ◽  
Author(s):  
Evgeny Kiselev ◽  
Nicholas Empey ◽  
Keli Agama ◽  
Yves Pommier ◽  
Mark Cushman
Keyword(s):  
Topoisomerase I ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Topoisomerase I Inhibitors ◽  
Synthesis And Biological Evaluation
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