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Benzodiazepine Receptor Ligands. 4. Synthesis and Pharmacological Evaluation of 3-Heteroaryl-8-chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-Oxides
Journal of Medicinal Chemistry
◽
10.1021/jm981126y
◽
1999
◽
Vol 42
(12)
◽
pp. 2218-2226
◽
Cited By ~ 27
Author(s):
Annarella Costanzo
◽
Gabriella Guerrini
◽
Giovanna Ciciani
◽
Fabrizio Bruni
◽
Silvia Selleri
◽
...
Keyword(s):
Benzodiazepine Receptor
◽
Receptor Ligands
◽
Benzodiazepine Receptor Ligands
◽
Pharmacological Evaluation
Download Full-text
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References
Benzodiazepine receptor ligands. 8: Synthesis and pharmacological evaluation of new pyrazolo[5,1-c] [1,2,4]benzotriazine 5-oxide 3- and 8-disubstituted: High affinity ligands endowed with inverse-agonist pharmacological efficacy
Bioorganic & Medicinal Chemistry
◽
10.1016/j.bmc.2005.08.058
◽
2006
◽
Vol 14
(3)
◽
pp. 758-775
◽
Cited By ~ 24
Author(s):
Gabriella Guerrini
◽
Annarella Costanzo
◽
Giovanna Ciciani
◽
Fabrizio Bruni
◽
Silvia Selleri
◽
...
Keyword(s):
Benzodiazepine Receptor
◽
Inverse Agonist
◽
Receptor Ligands
◽
Affinity Ligands
◽
Benzodiazepine Receptor Ligands
◽
High Affinity
◽
Pharmacological Evaluation
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ChemInform Abstract: Benzodiazepine Receptor Ligands. Synthesis and Preliminary Pharmacological Evaluation of Some 3,7-Disubstituted-4H-(1,2,4)Triazino(3,4-a)phthalazines and 3,7-Disubstituted-4H-(1,2,4)Triazino(3,4-a)phthalazin-4-ones.
ChemInform
◽
10.1002/chin.198938259
◽
1989
◽
Vol 20
(38)
◽
Author(s):
E. OCCELLI
◽
G. TARZIA
◽
D. BARONE
Keyword(s):
Benzodiazepine Receptor
◽
Receptor Ligands
◽
Benzodiazepine Receptor Ligands
◽
Pharmacological Evaluation
Download Full-text
Benzodiazepine receptor ligands. Synthesis and pharmacological evaluation of 3-, 7- and 8-substituted [5,1-c][1,2,4]benzotriazines and 5-oxide derivatives. Part I
European Journal of Medicinal Chemistry
◽
10.1016/0223-5234(96)80363-1
◽
1996
◽
Vol 31
(4)
◽
pp. 259-272
◽
Cited By ~ 14
Author(s):
G Guerrini
◽
A Costanzo
◽
F Bruni
◽
S Selleri
◽
L Casilli
◽
...
Keyword(s):
Benzodiazepine Receptor
◽
Receptor Ligands
◽
Benzodiazepine Receptor Ligands
◽
Pharmacological Evaluation
Download Full-text
Benzodiazepine Receptor Ligands. 7. Synthesis and Pharmacological Evaluation of New 3-Esters of the 8-Chloropyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide. 3-(2-Thienylmethoxycarbonyl) Derivative: An Anxioselective Agent in Rodents
Journal of Medicinal Chemistry
◽
10.1021/jm020944u
◽
2002
◽
Vol 45
(26)
◽
pp. 5710-5720
◽
Cited By ~ 16
Author(s):
Annarella Costanzo
◽
Gabriella Guerrini
◽
Giovanna Ciciani
◽
Fabrizio Bruni
◽
Camilla Costagli
◽
...
Keyword(s):
Benzodiazepine Receptor
◽
Receptor Ligands
◽
Benzodiazepine Receptor Ligands
◽
Pharmacological Evaluation
Download Full-text
ChemInform Abstract: Benzodiazepine Receptor Ligands. Synthesis and Pharmacological Evaluation of 6-Aryl-3,8-disubstituted-1,2,4-triazolo(3,4-a)phthalazines.
ChemInform
◽
10.1002/chin.198923193
◽
1989
◽
Vol 20
(23)
◽
Author(s):
G. TARZIA
◽
E. OCCELLI
◽
D. BARONE
Keyword(s):
Benzodiazepine Receptor
◽
Receptor Ligands
◽
Benzodiazepine Receptor Ligands
◽
Pharmacological Evaluation
Download Full-text
ChemInform Abstract: Benzodiazepine Receptor Ligands. Synthesis and Preliminary Pharmacological Evaluation of 2-Aminoalkyl-8-chloro- and 2-Aryl-1,2,4-triazolo-(3,4-a)phthalazin-3(2H)-ones.
ChemInform
◽
10.1002/chin.198938248
◽
1989
◽
Vol 20
(38)
◽
Author(s):
G. TARZIA
◽
E. OCCELLI
◽
N. CORSICO
◽
L. GALLICO
◽
F. LUZZANI
◽
...
Keyword(s):
Benzodiazepine Receptor
◽
Receptor Ligands
◽
Benzodiazepine Receptor Ligands
◽
Pharmacological Evaluation
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Peripheral benzodiazepine receptor ligands induce apoptosis and cell cycle arrest in human hepatocellular carcinoma cells and enhance chemosensitivity to paclitaxel, docetaxel, doxorubicin and the Bcl–2 inhibitor HA14–1
Zeitschrift für Gastroenterologie
◽
10.1055/s-2004-831695
◽
2004
◽
Vol 42
(08)
◽
Author(s):
A Sutter
◽
K Maaser
◽
P Grabowski
◽
M Höpfner
◽
A Krahn
◽
...
Keyword(s):
Hepatocellular Carcinoma
◽
Cell Cycle
◽
Cell Cycle Arrest
◽
Benzodiazepine Receptor
◽
Carcinoma Cells
◽
Peripheral Benzodiazepine Receptor
◽
Receptor Ligands
◽
Benzodiazepine Receptor Ligands
◽
Cycle Arrest
◽
Human Hepatocellular Carcinoma Cells
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Benzodiazepine Receptor Ligands, Memory and Information Processing
10.1007/978-3-642-73288-1
◽
1988
◽
Cited By ~ 5
Keyword(s):
Information Processing
◽
Benzodiazepine Receptor
◽
Receptor Ligands
◽
Benzodiazepine Receptor Ligands
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Benzodiazepine receptor ligands and sexual behavior in the male rat: The role of GABAergic mechanisms
Pharmacology Biochemistry and Behavior
◽
10.1016/0091-3057(91)90242-t
◽
1991
◽
Vol 38
(4)
◽
pp. 781-788
◽
Cited By ~ 10
Author(s):
Anders Ågmo
◽
Hilda Fernández
Keyword(s):
Sexual Behavior
◽
Benzodiazepine Receptor
◽
Male Rat
◽
Receptor Ligands
◽
Benzodiazepine Receptor Ligands
Download Full-text
Specific high-affinity binding of peripheral benzodiazepine receptor ligands to brain tumors in rat and man
Cancer
◽
10.1002/1097-0142(19900101)65:1<93::aid-cncr2820650120>3.0.co;2-1
◽
1990
◽
Vol 65
(1)
◽
pp. 93-97
◽
Cited By ~ 45
Author(s):
Keith L. Black
◽
Kiyonobu Ikezaki
◽
Emily Santori
◽
Donald P. Becker
◽
Harry V. Vinters
Keyword(s):
Brain Tumors
◽
Benzodiazepine Receptor
◽
Affinity Binding
◽
Peripheral Benzodiazepine Receptor
◽
Receptor Ligands
◽
High Affinity Binding
◽
Benzodiazepine Receptor Ligands
◽
High Affinity
Download Full-text
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