Application of elementoorganic compounds of 15th and 16th Groups in organic synthesis. 100. Reactions of carbonyl compounds with [(trimethylsilyl)propargyl]diisobutyltelluronium bromide mediated by different strong bases: highly regioselective synthesis of (trimethylsilyl)propargyl alcohols and highly stereoselective synthesis of cis-(trimethylsilyl)alkynyl epoxides

1992 ◽  
Vol 57 (24) ◽  
pp. 6598-6603 ◽  
Author(s):  
Zhanglin Zhou ◽  
Yaozeng Huang ◽  
Lilan Shi ◽  
Jiong Hu
Keyword(s):  
Organic Synthesis ◽  
Carbonyl Compounds ◽  
Stereoselective Synthesis ◽  
Regioselective Synthesis ◽  
Propargyl Alcohols

One-Pot, Regioselective Synthesis of Homopropargyl Alcohols using Propargyl Bromide and Carbonyl Compound by the Mg-mediated Reaction under Solvent-free Conditions

2020 ◽  
Vol 17 (6) ◽  
pp. 438-442
Author(s):  
Xiaofang Ma ◽  
Shunxi Li ◽  
Samrat Devaramani ◽  
Guohu Zhao ◽  
Daqian Xu
Keyword(s):  
Reaction Time ◽  
Organic Synthesis ◽  
Carbonyl Compounds ◽  
Solvent Free ◽  
Propargyl Bromide ◽  
Important Goal ◽  
One Pot ◽  
Short Reaction Time ◽  
Solvent Free Conditions ◽  
Volatile Organic

The elimination of volatile organic solvents in organic synthesis is the most important goal in “Green” chemistry. We report a simple, efficient and facile method for the addition of progargyl bromide to carbonyl compounds using Mg metal as a mediator under solvent-free conditions which could regioselectively generate homopropargyl alcohols efficiently in good to excellent yields. The procedure has advantages such as short reaction time, operationally simple, excellent product yields, high regioselectivity and organic solvent-free.

Hypervalent iodine in organic synthesis: α-functionalization of carbonyl compounds

1995 ◽  
Vol 2 (2) ◽  
pp. 121-131 ◽  
Author(s):  
Om Prakash ◽  
Neena Saini ◽  
Madan P. Tanwar ◽  
Robert M. Moriarty
Keyword(s):  
Organic Synthesis ◽  
Carbonyl Compounds ◽  
Hypervalent Iodine
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