New, easily removable poly(ethylene glycol) supports for the liquid-phase method of peptide synthesis

1980 ◽  
Vol 45 (26) ◽  
pp. 5364-5370 ◽  
Author(s):  
V. N. Rajasekharan Pillai ◽  
Manfred Mutter ◽  
Ernst Bayer ◽  
Ian Gatfield
Keyword(s):  
Liquid Phase ◽  
Ethylene Glycol ◽  
Peptide Synthesis ◽  
Phase Method ◽  
Poly Ethylene Glycol ◽  
Liquid Phase Method ◽  
Poly Ethylene

Synthesis of elastin-like peptides using the liquid phase method

1987 ◽  
Vol 52 (5) ◽  
pp. 1352-1355 ◽  
Author(s):  
M. E. Younes ◽  
S. Abdel Rahman ◽  
A. Hattaba
Keyword(s):  
Liquid Phase ◽  
Monomethyl Ether ◽  
Phase Method ◽  
Alternative Possibility ◽  
Poly Ethylene Glycol ◽  
Ethylene Glycol Monomethyl Ether ◽  
Glycol Monomethyl Ether ◽  
Conformational Studies ◽  
Liquid Phase Method ◽  
Poly Ethylene

Elastin-like peptides were synthesized by the liquid-phase method using poly(ethylene glycol) monomethyl ether (PEGM) (m.w. 5 000) as solubilizing support which provides an alternative possibility for conformational studies and spectroscopic measurements in solution. The following sequences were synthesized: Boc-Ala-Pro-Gly-Val-APEGM, Boc-Ala-Pro-Gly-Val-Gly-Val-APEGM, Boc-Ala-Pro-Gly-Val-Ala-Pro-Gly-Val-Gly-Val-APEGM, Boc-Ala-Pro-Gly-Val-Gly-Val-Ala-Pro-Gly-Val-Gly-Val-APEGM.

Synthesis and conformational investigation of β-turn forming tetra- and hexapeptides

1982 ◽  
Vol 47 (7) ◽  
pp. 1884-1892
Author(s):  
A. N. Abdel Rahman ◽  
S. Abdel Rahman
Keyword(s):  
Energy Transfer ◽  
Phase Method ◽  
Conformational Study ◽  
Poly Ethylene Glycol ◽  
High Solubility ◽  
Liquid Phase Method ◽  
Conformational Investigation ◽  
Transfer Method ◽  
Poly Ethylene ◽  
Good Agreement

Tetra- and hexapeptides containing Pro-Gly or Gly-Pro or Aib-Pro in their sequences were synthesized using the liquid-phase method. The high solubility of the poly(ethylene glycol) bound peptides in water and in organic solvents enables the application of the singlet-singlet energy transfer method for conformational investigation of these peptides. The conformational study in solid state by IR and in solution by CD were carried out in parallel to the energy transfer method. The qualitative results generated by IR and CD were found to be in good agreement with the quantitative end-to-end distances given by the energy transfer method.

Development and Application of a Poly(ethylene glycol)-Supported Triarylphosphine Reagent:  Expanding the Sphere of Liquid-Phase Organic Synthesis

1999 ◽  
Vol 64 (14) ◽  
pp. 5188-5192 ◽  
Author(s):  
Frank Sieber ◽  
Paul Wentworth ◽  
Jonathan D. Toker ◽  
Anita D. Wentworth ◽  
William A. Metz ◽  
...  
Keyword(s):  
Liquid Phase ◽  
Ethylene Glycol ◽  
Organic Synthesis ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

scholarly journals Exploiting Poly(ethylene glycol) as a Matrix for Liquid-Phase Organic Synthesis

Molecules ◽  
2000 ◽  
Vol 5 (12) ◽  
pp. 1018-1032 ◽  
Author(s):  
Frank Sieber ◽  
Paul Wentworth ◽  
Kim Janda
Keyword(s):  
Liquid Phase ◽  
Ethylene Glycol ◽  
Organic Synthesis ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Novel Traceless Liquid‐Phase Synthesis of Coumarin Derivatives on Poly(Ethylene Glycol) Support

2006 ◽  
Vol 36 (21) ◽  
pp. 3175-3181 ◽  
Author(s):  
Shou‐Ri Sheng ◽  
Pei‐Gang Huang ◽  
Qiong Wang ◽  
Ren Huang ◽  
Xiao‐Ling Liu
Keyword(s):  
Liquid Phase ◽  
Ethylene Glycol ◽  
Coumarin Derivatives ◽  
Poly Ethylene Glycol ◽  
Phase Synthesis ◽  
Poly Ethylene

Modeling of Liquid−Liquid Phase Equilibria in Aqueous Solutions of Poly(ethylene glycol) with a UNIFAC-Based Model

2003 ◽  
Vol 42 (21) ◽  
pp. 5399-5408 ◽  
Author(s):  
Efthimia A. Tritopoulou ◽  
Georgia D. Pappa ◽  
Epaminondas C. Voutsas ◽  
Ioannis G. Economou ◽  
Dimitrios P. Tassios
Keyword(s):  
Liquid Phase ◽  
Ethylene Glycol ◽  
Aqueous Solutions ◽  
Phase Equilibria ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene
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