Synthesis of β-C-Galactosyl Ceramide and Its New Aza Variant via the Horner–Wadsworth–Emmons Reaction

2014 ◽  
Vol 79 (11) ◽  
pp. 5193-5200 ◽  
Author(s):  
Jaggaiah N. Gorantla ◽  
Ravi S. Lankalapalli
Keyword(s):  
Galactosyl Ceramide

scholarly journals Synthesis and biological activity of α-l-fucosyl ceramides, analogues of the potent agonist, α-d-galactosyl ceramide KRN7000

2010 ◽  
Vol 20 (11) ◽  
pp. 3223-3226 ◽  
Author(s):  
Natacha Veerapen ◽  
Faye Reddington ◽  
Gabriel Bricard ◽  
Steven A. Porcelli ◽  
Gurdyal S. Besra
Keyword(s):  
Biological Activity ◽  
Potent Agonist ◽  
Galactosyl Ceramide

scholarly journals Galactosyl ceramide expressed on dendritic cells can mediate HIV-1 transfer from monocyte derived dendritic cells to autologous T cells

Virology ◽  
2007 ◽  
Vol 362 (1) ◽  
pp. 67-74 ◽  
Author(s):  
Aude Magérus-Chatinet ◽  
Huifeng Yu ◽  
Séverine Garcia ◽  
Elodie Ducloux ◽  
Benoit Terris ◽  
...  
Keyword(s):  
T Cells ◽  
Dendritic Cells ◽  
Galactosyl Ceramide ◽  
Hiv 1

The Galactosyl Ceramide/Sulfatide Receptor Binding Region of HIV-1 gp120 Maps to Amino Acids 206-275

1993 ◽  
Vol 9 (2) ◽  
pp. 175-181 ◽  
Author(s):  
SHAMA BHAT ◽  
RICHARD V. METTUS ◽  
E. PREMKUMAR REDDY ◽  
K.E. UGEN ◽  
V. SRIKANTHAN ◽  
...  
Keyword(s):  
Amino Acids ◽  
Receptor Binding ◽  
Binding Region ◽  
Galactosyl Ceramide ◽  
Receptor Binding Region ◽  
Hiv 1

Glycosylated α-Azido Amino Acids: Versatile Intermediates in the Synthesis of Neoglycoconjugates

Synlett ◽  
2018 ◽  
Vol 29 (07) ◽  
pp. 904-907 ◽  
Author(s):  
Trinidad Velasco-Torrijos ◽  
Róisín O’Flaherty
Keyword(s):  
Amino Acids ◽  
Drug Discovery ◽  
Building Blocks ◽  
Sensor Development ◽  
Galactosyl Ceramide

A series of glycosylated α-azido amino acids was synthesized as precursors for neoglycoconjugates, a class of important biomolecules for drug discovery, and sensor development. The synthetically challenging 1,2-cis α-galactosylated species described herein were designed as building blocks in the synthesis of analogues of α-galactosyl ceramide, a potent immunomodulator. A benzyl-protected 1,2,3-triazolyl α-galactosyl-l-serine derivative was prepared using copper azide alkyne cycloaddition to showcase the potential of glycosylated α-azido amino acids in neoglycoconjugate design.

Structure-Based Design of NH-modified α-Galactosyl Ceramide (KRN7000) Analogues and Their Biological Activities

2016 ◽  
Vol 1 (15) ◽  
pp. 4564-4569 ◽  
Author(s):  
Jung-Tung Hung ◽  
Ratnnadeep C. Sawant ◽  
Sheng-Hung Wang ◽  
Jing-Rong Huang ◽  
Chung-Li Huang ◽  
...  
Keyword(s):  
Biological Activities ◽  
Galactosyl Ceramide

Synthesis and Evaluation ofN-Acetyl-2-amino-2-deoxy-α-D-galactosyl 1-Thio-7-oxaceramide, a New Analogue ofα-D-Galactosyl Ceramide

2009 ◽  
Vol 92 (5) ◽  
pp. 918-927 ◽  
Author(s):  
Roshini Rajan ◽  
Thresen Mathew ◽  
Radovan Buffa ◽  
Frédéric Bornancin ◽  
Marco Cavallari ◽  
...  
Keyword(s):  
Galactosyl Ceramide

Inhibition of gp120 binding to galactosyl ceramide and sulfatide by potential anti-HIV compounds

AIDS ◽  
1992 ◽  
Vol 6 (10) ◽  
pp. 1213 ◽  
Author(s):  
S. Bhat ◽  
T. Otsuka ◽  
A. Srinivasan
Keyword(s):  
Gp120 Binding ◽  
Galactosyl Ceramide ◽  
Anti Hiv

The binding of HIV-1 gp41 membrane proximal domain to its mucosal receptor, galactosyl ceramide, is structure-dependent

Cell Calcium ◽  
2008 ◽  
Vol 43 (1) ◽  
pp. 73-82 ◽  
Author(s):  
Huifeng Yu ◽  
Annette Alfsen ◽  
Daniela Tudor ◽  
Morgane Bomsel
Keyword(s):  
Galactosyl Ceramide ◽  
Hiv 1
Sign in / Sign up

Export Citation Format

Share Document