Convenient Synthetic Route to an Enantiomerically Pure FMOC α-Amino Acid

2008 ◽  
Vol 73 (23) ◽  
pp. 9334-9339 ◽  
Author(s):  
Douglass F. Taber ◽  
James F. Berry ◽  
Timothy J. Martin
Keyword(s):  
Amino Acid ◽  
Synthetic Route ◽  
Enantiomerically Pure

ChemInform Abstract: Short Synthetic Route to the Enantiomerically Pure (R)-(+)-γ- Decalactone.

ChemInform ◽  
2010 ◽  
Vol 28 (1) ◽  
pp. no-no
Author(s):  
J. KULA ◽  
M. SIKORA ◽  
H. SADOWSKA ◽  
J. PIWOWARSKI
Keyword(s):  
Synthetic Route ◽  
Enantiomerically Pure

scholarly journals Enantiomerically Pure [2.2]Paracyclophane-4-thiol: A Planar Chiral Sulfur-Based Building Block Readily Available by Resolution with an Amino Acid Chiral Auxiliary

2016 ◽  
Vol 81 (9) ◽  
pp. 3961-3966 ◽  
Author(s):  
Adrien Vincent ◽  
Damien Deschamps ◽  
Thomas Martzel ◽  
Jean-François Lohier ◽  
Christopher J. Richards ◽  
...  
Keyword(s):  
Amino Acid ◽  
Building Block ◽  
Chiral Auxiliary ◽  
Enantiomerically Pure

Amino acid based enantiomerically pure 3-substituted benzofused heterocycles: A new class of antithrombotic agents

2010 ◽  
Vol 20 (1) ◽  
pp. 244-247 ◽  
Author(s):  
Jitendra Kumar Mishra ◽  
Krishnananda Samanta ◽  
Manish Jain ◽  
Madhu Dikshit ◽  
Gautam Panda
Keyword(s):  
Amino Acid ◽  
Antithrombotic Agents ◽  
Enantiomerically Pure ◽  
New Class

Significantly Contrasting Solid State Dynamics of the Racemic and Enantiomerically Pure Crystalline Forms of an Amino Acid

2005 ◽  
Vol 109 (48) ◽  
pp. 22808-22813 ◽  
Author(s):  
Simon J. Kitchin ◽  
Gianina Tutoveanu ◽  
Matthew R. Steele ◽  
Elaine L. Porter ◽  
Kenneth D. M. Harris
Keyword(s):  
Amino Acid ◽  
Solid State ◽  
Enantiomerically Pure ◽  
Crystalline Forms

scholarly journals On the preparation of enantiomerically pure isonitriles from amino acid esters and peptides

2009 ◽  
Vol 50 (5) ◽  
pp. 577-579 ◽  
Author(s):  
Jianglong Zhu ◽  
Xiangyang Wu ◽  
Samuel J. Danishefsky
Keyword(s):  
Amino Acid ◽  
Amino Acid Esters ◽  
Enantiomerically Pure ◽  
Acid Esters

Exploring the reaction of formaldehyde with α-N-protected amino acid hydrazides

2008 ◽  
Vol 86 (7) ◽  
pp. 714-719
Author(s):  
Giancarlo Verardo ◽  
Paola Geatti ◽  
Marta Mancuso ◽  
Paolo Strazzolini
Keyword(s):  
High Temperature ◽  
Amino Acid ◽  
Monomeric Form ◽  
Enantiomerically Pure ◽  
Final Reaction ◽  
Protected Amino Acid ◽  
Condensation Reactions ◽  
C Nmr ◽  
Aqueous Formaldehyde

The reaction of formaldehyde with enantiomerically pure α-N-protected amino acid hydrazides is described. The system has been investigated in different solvents, including both aqueous formaldehyde and paraformaldehyde, with the aim of simplifying the final reaction mixture. Aqueous formaldehyde in refluxing THF proved to be the best combination, affording mainly the corresponding monomeric N-methylene and 1,3,5-trisubstituted-1,3,5-hexahydrotriazine derivatives. The monomeric form was the only one present at high temperature, as evidenced by 1H and 13C NMR spectroscopy.Key words: amino acid hydrazides, formaldehyde, condensation reactions, monomeric N-methylene derivatives, oligomers.

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