Selective and Sensitive Ratiometric Detection of Hg(II) Ions Using a Simple Amino Acid Based Sensor

2011 ◽  
Vol 13 (19) ◽  
pp. 5028-5031 ◽  
Author(s):  
Mi-Hwa Yang ◽  
Ponnaboina Thirupathi ◽  
Keun-Hyeung Lee
Keyword(s):  
Amino Acid ◽  
Ratiometric Detection ◽  
Simple Amino Acid

Insertion of oximic and hydroxamic functions into one simple amino acid creates a new family of powerful chelating agents

1998 ◽  
pp. 1089-1090 ◽  
Author(s):  
Agnieszka Dobosz ◽  
Igor O. Fritsky ◽  
Aldona Karaczyn ◽  
Henryk Kozłowski ◽  
Tatiana Yu. Sliva ◽  
...  
Keyword(s):  
Amino Acid ◽  
Chelating Agents ◽  
New Family ◽  
Simple Amino Acid

scholarly journals Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia

Blood ◽  
2019 ◽  
Vol 134 (19) ◽  
pp. 1632-1644 ◽  
Author(s):  
Karen Aymonnier ◽  
Charlotte Kawecki ◽  
Laurence Venisse ◽  
Yacine Boulaftali ◽  
Olivier D. Christophe ◽  
...  
Keyword(s):  
Amino Acid ◽  
Protein C ◽  
Activated Protein C ◽  
Therapeutic Strategies ◽  
Amino Acid Substitutions ◽  
Contact Activation ◽  
Elastase Inhibitor ◽  
Hemostatic System ◽  
Protease Nexin ◽  
Simple Amino Acid

Targeting natural anticoagulant proteins as a means to rebalance the hemostatic system is an emerging trend in the development of innovative therapeutic strategies for hemophilia. These 2 articles develop these concepts in the areas of hemostasis and contact activation. In the study by Aymonnier and colleagues, simple amino acid substitutions converted a serpin elastase inhibitor, α1-antitrypsin (α1AT), into a potent antithrombin, activated protein C inhibitor, or anti-PKa/FXIIa inhibitor. In the study by de Maat and colleagues, redesign of α1AT strongly altered its inhibitory behavior and enables it to be used for the treatment of contact system–mediated thrombosis and inflammation.

SOME AROMAS PRODUCED BY SIMPLE AMINO ACID, SUGAR REACTIONSb

1960 ◽  
Vol 25 (4) ◽  
pp. 491-494 ◽  
Author(s):  
W. J. HERZ ◽  
R. S. SHALLENBERGER
Keyword(s):  
Amino Acid ◽  
Simple Amino Acid

Special Evolutionary Properties of Genes Encoding a Protein with a Simple Amino Acid Repeat

2001 ◽  
Vol 53 (3) ◽  
pp. 180-190 ◽  
Author(s):  
Traci Meeds ◽  
Erin Lockard ◽  
Brian T. Livingston
Keyword(s):  
Amino Acid ◽  
Amino Acid Repeat ◽  
Genes Encoding ◽  
Simple Amino Acid

Hydration and aggregation of a simple amino acid: The case of glycine

2020 ◽  
Vol 301 ◽  
pp. 112407 ◽  
Author(s):  
Michael Di Gioacchino ◽  
Maria Antonietta Ricci ◽  
Silvia Imberti ◽  
Nicole Holzmann ◽  
Fabio Bruni
Keyword(s):  
Amino Acid ◽  
Simple Amino Acid

scholarly journals Improving Protein Pharmacokinetics by Genetic Fusion to Simple Amino Acid Sequences

2003 ◽  
Vol 279 (5) ◽  
pp. 3375-3381 ◽  
Author(s):  
Paula Alvarez ◽  
Carlos A. Buscaglia ◽  
Oscar Campetella
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequences ◽  
Genetic Fusion ◽  
Simple Amino Acid

Evolution of a new function in an esterase: simple amino acid substitutions enable the activity present in the larger paralog, BioH

2012 ◽  
Vol 25 (8) ◽  
pp. 387-395 ◽  
Author(s):  
H. Flores ◽  
S. Lin ◽  
G. Contreras-Ferrat ◽  
J. E. Cronan ◽  
E. Morett
Keyword(s):  
Amino Acid ◽  
Amino Acid Substitutions ◽  
Simple Amino Acid
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