Synthesis of Pyridazine-Based Scaffolds as α-Helix Mimetics

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Α Helix ◽  

Key residues on opposing faces of the Bak-BH3 α-helix were recapitulated by the 2,6,9-tri-substitution of a purine scaffold.


ChemMedChem ◽  
2020 ◽  
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