scholarly journals An Efficient Synthesis of β-C-Glycosides Based on the Conformational Restriction Strategy: Lewis Acid Promoted Silane Reduction of the Anomeric Position with Complete Stereoselectivity

2010 ◽  
Vol 12 (2) ◽  
pp. 400-400 ◽  
Author(s):  
Masaru Terauchi ◽  
Hiroshi Abe ◽  
Akira Matsuda ◽  
Satoshi Shuto
Keyword(s):  
Lewis Acid ◽  
Efficient Synthesis ◽  
Conformational Restriction ◽  
Restriction Strategy

Efficient Synthesis of Diarylmethylamines via Lewis Acid Catalyzed Friedel–Crafts Reactions of Donor–Acceptor Aziridines with N,N-Dialkylanilines

Synthesis ◽  
2019 ◽  
Vol 52 (02) ◽  
pp. 281-289
Author(s):  
Yerin Kim ◽  
Yong Il Kwon ◽  
Sung-Gon Kim
Keyword(s):  
Lewis Acid ◽  
Efficient Synthesis ◽  
Broad Scope ◽  
Donor Acceptor ◽  
Acid Catalyzed ◽  
High Yields

A method for efficient and mild synthesis of diarylmethylamine scaffold, via Lewis acid catalyzed Friedel–Crafts reaction of donor­–acceptor aziridines with N,N-dialkylanilines to afford a biologically important diarylmethylamine derivatives in high yields (up to 88%), is presented. This reaction is suitable for the synthesis of various diarylmethylamine derivatives and has a broad scope for electron-rich arenes, including dimethoxybenzene.

Generation of tricyclic imidazo[1,2- a ]pyrazines as novel PI3K inhibitors by application of a conformational restriction strategy

2017 ◽  
Vol 27 (11) ◽  
pp. 2536-2543 ◽  
Author(s):  
Sonia Martínez González ◽  
Sonsoles Rodríguez-Arístegui ◽  
Ana Isabel Hernández ◽  
Carmen Varela ◽  
Esther González Cantalapiedra ◽  
...  
Keyword(s):  
Conformational Restriction ◽  
Pi3k Inhibitors ◽  
Restriction Strategy

One-Pot Heck and Reduction: Application towards Efficient Synthesis of Flavans Promoted by Lewis Acid

2017 ◽  
Vol 2 (33) ◽  
pp. 10809-10813 ◽  
Author(s):  
Nishu Rana ◽  
Pedireddi Niharika ◽  
Dakoju Ravi Kishore ◽  
Gedu Satyanarayana
Keyword(s):  
Lewis Acid ◽  
Efficient Synthesis ◽  
One Pot
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