Dilute (d) coat colour mutation of DBA/2J mice is associated with the site of integration of an ecotropic MuLV genome

Nature ◽  
1981 ◽  
Vol 293 (5831) ◽  
pp. 370-374 ◽  
Author(s):  
Nancy A. Jenkins ◽  
Neal G. Copeland ◽  
Benjamin A. Taylor ◽  
Barbara K. Lee
Keyword(s):  



2013 ◽  
Vol 56 (1) ◽  
pp. 42-49
Author(s):  
L. Fontanesi ◽  
E. Scotti ◽  
M. Colombo ◽  
D. Allain ◽  
S. Deretz ◽  
...  

Abstract. After the rediscovery of the Mendel’s laws, the domesticated European rabbit (Orycolagus cuniculus) has been the objective of pioneering studies on coat colour genetics. However, despite the early role of this species in defining genetic mechanisms determining this phenotypic trait, only recently a few loci have been characterized at the molecular level analysing also in rabbits genes already shown to affect coat colour in mice. We herein investigated the rabbit premelanosome protein (PMEL) gene, also known as melanocyte protein Pmel 17 (PMEL17) or silver (SILV), as mutations in the homologous gene in mice and other species produce phenotypic effects similar to what is observed in the dilute coat colour in rabbit. The rabbit dilute locus is determined by a recessive coat colour mutation that dilutes the black to blue (grey) interacting with the basic colours influenced by the agouti and extension loci. To investigate this candidate gene, we isolated and sequenced cDNAs as well as portions of intronic and exonic regions of the PMEL gene in several rabbits with different coat colours and identified single nucleotide polymorphisms, including several missense mutations. One polymorphism, positioned in intron 7, was genotyped in a family in which there was segregation of the dilute coat colour. The results excluded PMEL as the causative gene for the dilute locus in rabbits, shortening the list of candidate genes that should be analysed to identify the mutation determining this phenotypic trait.



1979 ◽  
Vol 33 (2) ◽  
pp. 163-167
Author(s):  
Jean-Louis Guenet
Keyword(s):  

SUMMARYA sex-linked mutation with a phenotype similar to that of an allele of the Mottled series has been discovered in a mosaic male. This mutation can be normally transmitted through the sperm of the original male but not through the oocytes. Several interpretations of this abnormal transmission are discussed.



2007 ◽  
Vol 22 (1) ◽  
pp. 43-49
Author(s):  
Anna Stachurska ◽  
Anne P. Ussing
Keyword(s):  


2021 ◽  
Author(s):  
Riana van Deventer ◽  
Clint Rhode ◽  
Munro Marx ◽  
Rouvay Roodt-Wilding
Keyword(s):  


2020 ◽  
Vol 19 (1) ◽  
pp. 1508-1512
Author(s):  
Stefano Pallotti ◽  
Bathrachalam Chandramohan ◽  
Dario Pediconi ◽  
Cristina Nocelli ◽  
Antonietta La Terza ◽  
...  


1912 ◽  
Vol 2 (3) ◽  
pp. 221-238 ◽  
Author(s):  
R. C. Punnett
Keyword(s):  


1966 ◽  
Vol 8 (1) ◽  
pp. 111-113 ◽  
Author(s):  
D. S. Falconer ◽  
J. H. Isaacson

Curly-whiskers (cw) is a recessive gene which was found in 1958 by Mr C. J. W. Smith of the Chester Beatty Research Institute, London. It arose in a subline of the CBA/Cbi inbred strain. The first mutant animals were one male and one female in a litter of five. The two mutants were mated together and a sib-mated subline was continued from them in which 500 mice were bred, all of which were curly-whiskered. This established the mutant to be fully penetrant. Curly-whiskers resembles the hair-waving genes in causing waving of the vibrissae, but it has no obvious waving effect on the hairs of the coat. The coat texture is, however, slightly abnormal and Mr Smith noted also that on the CBA background there was an appreciable darkening of the coat colour. Homozygotes (cw/cw) are easily classifiable soon after birth by the curled vibrissae. Heterozygotes (+/cw) often have slightly curled vibrissae, and the gene is therefore not fully recessive; but the distinction between +/cw and +/+ could not be relied on, and in the linkage tests cw was treated as a recessive gene.



2003 ◽  
Vol 34 (3) ◽  
pp. 169-175 ◽  
Author(s):  
T. G. Berryere ◽  
S. M. Schmutz ◽  
R. J. Schimpf ◽  
C. M. Cowan ◽  
J. Potter
Keyword(s):  


1970 ◽  
Vol 6 (1) ◽  
pp. 27-31 ◽  
Author(s):  
M. Osman Khidir ◽  
H. El Gizouli Osman

SummaryIn 90 local sesame types there was some association between seed coat colour and seed size, stem height, number of branches, number of pods, yield per plant and earliness. Forty-five coefficients show the degree of correlation between ten agronomic characters. Yield was significantly and positively correlated with all characters except the number of days to first flowering and to first maturity. Stem height, number of pods per plant and seed size seem to be the best criteria for selection in sesame.



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