scholarly journals Stem cell therapy for Alzheimer’s disease and related disorders: current status and future perspectives

2015 ◽  
Vol 47 (3) ◽  
pp. e151-e151 ◽  
Author(s):  
Leslie M Tong ◽  
Helen Fong ◽  
Yadong Huang
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Current Status ◽  
Future Perspectives

Mesenchymal Stem Cell Therapy and Alzheimer’s Disease: Current Status and Future Perspectives

2020 ◽  
Vol 77 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Jieun Kim ◽  
Yujeong Lee ◽  
Seulah Lee ◽  
Kipom Kim ◽  
Minjung Song ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Stem Cells ◽  
Stem Cell ◽  
Cell Therapy ◽  
Neurodegenerative Disease ◽  
Stem Cell Therapy ◽  
Amyloid Β ◽  
Research Trends ◽  
Current Status

Alzheimer’s disease (AD) is the most common progressive neurodegenerative disease worldwide, but its cause remains unclear. Although a few drugs can provide temporary and partial relief of symptoms in some patients, no curative treatment is available. Therefore, attention has been focused on research using stem cells to treat AD. Among stem cells, mesenchymal stem cells (MSCs) have been used to treat the related pathologies in animal models of AD, and other neurodegenerative disease. This review describes latest research trends on the use of MSC-based therapies in AD and its action of mechanism. MSCs have several beneficial effects. They would be specified as the reduction of neuroinflammation, the elimination of amyloid-β, neurofibrillary tangles, and abnormal protein degradation, the promotion of autophagy-associated and blood-brain barrier recoveries, the upregulation of acetylcholine levels, improved cognition, and the recovery of mitochondrial transport. Therefore, this review describes the latest research trends in MSC-based therapy for AD by demonstrating the importance of MSC-based therapy and understanding of its mechanisms in AD and discusses the limitations and perspectives of stem cell therapy in AD.

scholarly journals Current status and future prospects of stem cell therapy in Alzheimer’s disease

2020 ◽  
Vol 15 (2) ◽  
pp. 242 ◽  
Author(s):  
Xue-Qi Fu ◽  
Lin-Lin Zeng ◽  
Fu-Qiang Zhang ◽  
Jin-Lan Jiang ◽  
Jing-Tian Zhang ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Current Status ◽  
Future Prospects

scholarly journals Analysis of the Expectation of Stem Cell Therapy in Patients with Alzheimer’s Disease

2016 ◽  
Vol 15 (4) ◽  
pp. 129
Author(s):  
Seokgil Han ◽  
Hojin Choi ◽  
Young Seo Kim ◽  
Kyu-Yong Lee ◽  
Young Joo Lee ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy

P3-345: Restoration of memory in mouse models of Alzheimer's disease and neuronal loss: A new paradigm using human neural stem cell therapy

2012 ◽  
Vol 8 (4S_Part_16) ◽  
pp. P577-P578
Author(s):  
Mathew Blurton-Jones ◽  
Rahasson Ager ◽  
Joy Nerhus ◽  
Andy Agazaryan ◽  
Stephen Huhn ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Stem Cell ◽  
Cell Therapy ◽  
Neural Stem Cell ◽  
Mouse Models ◽  
Stem Cell Therapy ◽  
Neuronal Loss ◽  
New Paradigm ◽  
Human Neural Stem Cell

Stem cell therapy in Alzheimer’s disease: possible benefits and limiting drawbacks

2018 ◽  
Vol 46 (1) ◽  
pp. 1425-1446 ◽  
Author(s):  
Masoume Alipour ◽  
Seyed Massood Nabavi ◽  
Leila Arab ◽  
Massoud Vosough ◽  
Hossein Pakdaman ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy

Translating Stem Cell Therapy for Alzheimer’s Disease

2015 ◽  
pp. 1233-1238
Author(s):  
Kazutaka Shinozuka ◽  
Paolina Pantcheva ◽  
Sandra Acosta ◽  
Mibel Pabon ◽  
Naoki Tajiri ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Stem Cell ◽  
Cell Therapy ◽  
Stem Cell Therapy
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