scholarly journals Bruch’s membrane opening-based optical coherence tomography of the optic nerve head: a useful diagnostic tool to detect glaucoma in macrodiscs

Eye ◽  
2018 ◽  
Vol 32 (2) ◽  
pp. 314-323 ◽  
Author(s):  
P Enders ◽  
F Schaub ◽  
W Adler ◽  
M M Hermann ◽  
T S Dietlein ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Diagnostic Tool ◽  
Optical Coherence ◽  
Bruch's Membrane ◽  
Bruch’S Membrane ◽  
Bruch’S Membrane Opening

scholarly journals Bruch’s membrane opening enlargement and its implication on the myopic optic nerve head

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Mi Sun Sung ◽  
Min Young Heo ◽  
Hwan Heo ◽  
Sang Woo Park
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Head ◽  
Lamina Cribrosa ◽  
Cross Sectional Study ◽  
Multivariate Regression Model ◽  
Bruch's Membrane ◽  
Bruch’S Membrane ◽  
Cross Sectional ◽  
Bruch’S Membrane Opening ◽  
Parapapillary Atrophy

AbstractWe examined the association between Bruch’s membrane opening (BMO) area and various ocular parameters and investigated the implication of BMO enlargement on the myopic optic nerve head. One hundred eighty-five myopic eyes were included in this cross-sectional study. Among the included eyes, 53 having axial lengths between 26 and 27 mm were further analyzed to investigate the association between BMO area and various ocular parameters. BMO area, BMO-minimum rim width (BMO-MRW), peripapillary choroidal thickness (pCT), width of β-parapapillary atrophy with and without Bruch’s membrane (PPA+BM and PPA−BM), and presence of lamina cribrosa (LC) defect were evaluated. We found that BMO area tended to increase with increasing axial length, but varied among the highly myopic eyes even though they had similar degrees of myopia. In the subgroup analysis of eyes with axial lengths between 26 and 27 mm, BMO area was highly variable and it significantly correlated with PPA−BM width and temporal-inferior, nasal-inferior, and nasal BMO-MRW and pCT. LC defects were more common in myopic eyes with enlarged BMO. A multivariate regression model revealed that higher intraocular pressure, enlarged BMO, and thinner BMO-MRW were associated with LC defects in highly myopic eyes. These findings should be considered when evaluating myopic eyes.

Influence of Bruch's Membrane Opening Area in Diagnosing Glaucoma With Neuroretinal Parameters From Optical Coherence Tomography

2019 ◽  
Vol 208 ◽  
pp. 94-102 ◽  
Author(s):  
Lucas A. Torres ◽  
Glen P. Sharpe ◽  
Donna M. Hutchison ◽  
Camila S. Zangalli ◽  
Reinhard O. Burk ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Bruch's Membrane ◽  
Bruch’S Membrane ◽  
Bruch’S Membrane Opening

scholarly journals Comparing optical coherence tomography radial and cube scan patterns for measuring Bruch’s membrane opening minimum rim width (BMO-MRW) in glaucoma and healthy eyes: cross-sectional and longitudinal analysis

2017 ◽  
Vol 102 (3) ◽  
pp. 344-351 ◽  
Author(s):  
Sami W Kabbara ◽  
Linda M Zangwill ◽  
Rusdeep Mundae ◽  
Naama Hammel ◽  
Christopher Bowd ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Characteristic Curve ◽  
Optical Coherence ◽  
Bruch's Membrane ◽  
Bruch’S Membrane ◽  
Significant Difference ◽  
Bruch’S Membrane Opening ◽  
Scan Pattern ◽  
Healthy Eyes ◽  
Sd Oct

AimTo compare the cube and radial scan patterns of the spectral domain optical coherence tomography (SD-OCT) for quantifying the Bruch’s membrane opening minimum rim width (BMO-MRW).MethodsSixty healthy eyes and 189 glaucomatous eyes were included. The optic nerve head cube and radial pattern scans were acquired using Spectralis SD-OCT. BMO-MRWs were automatically delineated using the San Diego Automated Layer Segmentation Algorithm. The BMO-MRW diagnostic accuracy for glaucoma detection and rates of change derived from the two scan patterns were compared.ResultsThere was a significant difference between the baseline global BMO-MRW measurements of cube and radial scans for healthy (301.9±57.8 µm and 334.7±61.8 µm, respectively, p<0.003) and glaucoma eyes (181.2±63.0 µm and 210.2±67.2 µm, respectively, p<0.001). The area under the receiver operating characteristic curve for differentiating between healthy and glaucoma eyes was 0.90 for both the radial scan-based and cube scan-based BMO-MRW. No significant difference in the rate of BMO-MRW change (mean follow-up years) by scan pattern was found among both healthy (cube: −1.47 µm/year, radial: −1.53 µm/year; p=0.48) (1.6 years) and glaucoma eyes (cube: −2.37 µm/year, radial: −2.28 µm/year; p=0.45) (2.6 years).ConclusionAlthough the cube scan-based BMO-MRW was significantly smaller than the radial scan-based BMO-MRW, we found no significant difference between the two scan patterns for detecting glaucoma, identifying BMO location and measuring the rate of BMO-MRW change. These results suggest that although BMO-MRW estimates are not interchangeable, both scan patterns can be used for monitoring BMO-MRW changes over time.

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