scholarly journals MHC-independent genetic regulation of liver damage in a mouse model of autoimmune hepatocellular injury

2005 ◽  
Vol 85 (4) ◽  
pp. 550-561 ◽  
Author(s):  
Jack T Lin ◽  
Tamar J Kitzmiller ◽  
Justin M M Cates ◽  
James D Gorham
Keyword(s):  
Mouse Model ◽  
Liver Damage ◽  
Genetic Regulation ◽  
Hepatocellular Injury

Curcumin ameliorates liver damage and progression of NASH in NASH-HCC mouse model possibly by modulating HMGB1-NF-κB translocation

2017 ◽  
Vol 44 ◽  
pp. 174-182 ◽  
Author(s):  
Rejina Afrin ◽  
Somasundaram Arumugam ◽  
Azizur Rahman ◽  
Mir Imam Ibne Wahed ◽  
Vengadeshprabhu Karuppagounder ◽  
...  
Keyword(s):  
Mouse Model ◽  
Liver Damage

scholarly journals TNF-alpha inhibition ameliorates HDV-induced liver damage in a mouse model of acute severe infection

JHEP Reports ◽  
2020 ◽  
Vol 2 (3) ◽  
pp. 100098 ◽  
Author(s):  
Carla Usai ◽  
Sheila Maestro ◽  
Gracian Camps ◽  
Cristina Olague ◽  
Lester Suárez-Amaran ◽  
...  
Keyword(s):  
Mouse Model ◽  
Liver Damage ◽  
Severe Infection ◽  
Tnf Alpha

A Gene Therapy Approach to Improve Copper Metabolism and Prevent Liver Damage in a Mouse Model of Wilson Disease

2019 ◽  
Vol 30 (1) ◽  
pp. 29-39 ◽  
Author(s):  
Jenny A. Greig ◽  
Jayme M. L. Nordin ◽  
Melanie K. Smith ◽  
Scott N. Ashley ◽  
Christine Draper ◽  
...  
Keyword(s):  
Gene Therapy ◽  
Mouse Model ◽  
Liver Damage ◽  
Wilson Disease ◽  
Copper Metabolism ◽  
Therapy Approach ◽  
Gene Therapy Approach

Indoline derivatives mitigate liver damage in a mouse model of acute liver injury

2017 ◽  
Vol 69 (5) ◽  
pp. 894-902 ◽  
Author(s):  
Efrat Finkin-Groner ◽  
Shlomi Finkin ◽  
Shani Zeeli ◽  
Marta Weinstock
Keyword(s):  
Liver Injury ◽  
Mouse Model ◽  
Liver Damage ◽  
Acute Liver Injury

Impact and mechanisms of insulin resistance on liver damage progression in a mouse model of non-alcoholic steatohepatitis (NASH)

2016 ◽  
Vol 48 ◽  
pp. e11 ◽  
Author(s):  
M. Meroni ◽  
P. Dongiovanni ◽  
G.A. Baselli ◽  
R. Rametta ◽  
S. Gatti ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Mouse Model ◽  
Liver Damage ◽  
Alcoholic Steatohepatitis ◽  
Damage Progression

Genetic Regulation of Gelsolin in Lung in Mouse Model and its Potential Broad Spectrum of Biological Functions

2016 ◽  
Vol 12 (3) ◽  
Author(s):  
Xiaoyun Liu ◽  
Helin Feng ◽  
Jiaqian Zhu ◽  
Rachel Stein ◽  
Yue Huang ◽  
...  
Keyword(s):  
Mouse Model ◽  
Broad Spectrum ◽  
Genetic Regulation ◽  
Biological Functions

scholarly journals Development of an HSV-tk transgenic mouse model for study of liver damage

FEBS Journal ◽  
2005 ◽  
Vol 272 (9) ◽  
pp. 2207-2215 ◽  
Author(s):  
Yan Zhang ◽  
Shu-Zhen Huang ◽  
Shu Wang ◽  
Yi-Tao Zeng
Keyword(s):  
Mouse Model ◽  
Transgenic Mouse ◽  
Liver Damage ◽  
Transgenic Mouse Model

Smad7 regulates compensatory hepatocyte proliferation in damaged mouse liver and positively relates to better clinical outcome in human hepatocellular carcinoma

2015 ◽  
Vol 128 (11) ◽  
pp. 761-774 ◽  
Author(s):  
Teng Feng ◽  
Johanna Dzieran ◽  
Xing Gu ◽  
Silke Marhenke ◽  
Arndt Vogel ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Clinical Outcome ◽  
Mouse Model ◽  
Liver Damage ◽  
Mouse Liver ◽  
Human Hepatocellular Carcinoma ◽  
Hepatocyte Proliferation ◽  
Smad7 Expression ◽  
Dependent Mechanism

In an early liver damage mouse model, Smad7 induced compensatory hepatocyte proliferation. High Smad7 expression was associated with better prognosis in human hepatocellular carcinoma, especially in distinct subgroups. A YB-1 dependent mechanism was involved in Smad7 up-regulation in HCC.

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