Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice

Cheng Xue Qin; Lauren T. May; Renming Li; Nga Cao; Sarah Rosli; Minh Deo; Amy E. Alexander; Duncan Horlock; Jane E. Bourke; Yuan H. Yang; Alastair G. Stewart; David M. Kaye; Xiao-Jun Du; Patrick M. Sexton; Arthur Christopoulos; Xiao-Ming Gao; Rebecca H. Ritchie

doi:10.1038/ncomms14232

Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice

Nature Communications ◽

10.1038/ncomms14232 ◽

2017 ◽

Vol 8 (1) ◽

Cited By ~ 41

Author(s):

Cheng Xue Qin ◽

Lauren T. May ◽

Renming Li ◽

Nga Cao ◽

Sarah Rosli ◽

...

Keyword(s):

Reperfusion Injury ◽

Small Molecule ◽

Myocardial Ischaemia ◽

Receptor Agonist ◽

Formyl Peptide Receptor ◽

Ischaemia Reperfusion Injury ◽

Peptide Receptor ◽

Ischaemia Reperfusion ◽

Formyl Peptide

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Correspondence: Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury

Nature Communications ◽

10.1038/s41467-017-02654-2 ◽

2018 ◽

Vol 9 (1) ◽

Cited By ~ 3

Author(s):

Agostino Cilibrizzi

Keyword(s):

Reperfusion Injury ◽

Formyl Peptide Receptor ◽

Ischaemia Reperfusion Injury ◽

Biased Agonism ◽

Peptide Receptor ◽

Ischaemia Reperfusion ◽

Formyl Peptide ◽

Cardioprotective Effects

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Correspondence: Reply to ‘Compound 17b and formyl peptide receptor biased agonism in relation to cardioprotective effects in ischaemia-reperfusion injury’

Nature Communications ◽

10.1038/s41467-017-02656-0 ◽

2018 ◽

Vol 9 (1) ◽

Cited By ~ 2

Author(s):

Cheng Xue Qin ◽

Lauren T. May ◽

Patrick M. Sexton ◽

Aaron J. DeBono ◽

Jonathan B. Baell ◽

...

Keyword(s):

Reperfusion Injury ◽

Formyl Peptide Receptor ◽

Ischaemia Reperfusion Injury ◽

Biased Agonism ◽

Peptide Receptor ◽

Ischaemia Reperfusion ◽

Formyl Peptide ◽

Cardioprotective Effects

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The Time Course of Cardioprotection Induced by GR79236, a Selective Adenosine A1-Receptor Agonist, in Myocardial Ischaemia-Reperfusion Injury in the Pig

Journal of Cardiovascular Pharmacology ◽

10.1097/00005344-199902000-00016 ◽

1999 ◽

Vol 33 (2) ◽

pp. 285-291 ◽

Cited By ~ 41

Author(s):

J. B. Louttit ◽

A. A. E. Hunt ◽

M. P. Maxwell ◽

G. M. Drew

Keyword(s):

Reperfusion Injury ◽

Myocardial Ischaemia ◽

Receptor Agonist ◽

Time Course ◽

Adenosine A1 Receptor ◽

Ischaemia Reperfusion Injury ◽

Ischaemia Reperfusion ◽

Adenosine A1 ◽

A1 Receptor

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Post-ischaemic administration of a3 adenosine receptor agonist ameliorates myocardial ischaemia–reperfusion injury via ERK 1/2

Journal of Molecular and Cellular Cardiology ◽

10.1016/j.yjmcc.2006.03.160 ◽

2006 ◽

Vol 40 (6) ◽

pp. 974 ◽

Cited By ~ 1

Author(s):

A. Hussain ◽

H. Al-Rajaibi ◽

P. Karjian ◽

H.L. Maddock

Keyword(s):

Reperfusion Injury ◽

Myocardial Ischaemia ◽

Adenosine Receptor ◽

Receptor Agonist ◽

Ischaemia Reperfusion Injury ◽

Ischaemia Reperfusion ◽

Adenosine Receptor Agonist ◽

A3 Adenosine Receptor

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Formyl Peptide Receptor (FPR) Biased Agonists as Novel Cardioprotection from Myocardial Ischaemia-reperfusion (I-R) Injury

Heart Lung and Circulation ◽

10.1016/j.hlc.2016.06.003 ◽

2016 ◽

Vol 25 ◽

pp. S1-S2

Author(s):

C. Qin ◽

L. May ◽

R. Li ◽

N. Cao ◽

S. Rosli ◽

...

Keyword(s):

Myocardial Ischaemia ◽

Formyl Peptide Receptor ◽

Peptide Receptor ◽

Ischaemia Reperfusion ◽

Formyl Peptide

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Screening and identification of differentially expressed genes in myocardial ischaemia/reperfusion injury using suppression subtractive hybridization

Acta Cardiologica ◽

10.2143/ac.63.2.2029531 ◽

2008 ◽

Vol 63 (2) ◽

pp. 213-219 ◽

Cited By ~ 1

Author(s):

Y-W. Liu ◽

S-P. Liu ◽

J-D. Cheng ◽

K. Wang ◽

Y-C. Chen

Keyword(s):

Reperfusion Injury ◽

Differentially Expressed Genes ◽

Suppression Subtractive Hybridization ◽

Myocardial Ischaemia ◽

Subtractive Hybridization ◽

Differentially Expressed ◽

Ischaemia Reperfusion Injury ◽

Ischaemia Reperfusion ◽

Screening And Identification

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Hypertrophic Preconditioning Cardioprotection After Myocardial Ischaemia/Reperfusion Injury Involves ALDH2-Dependent Metabolism Modulation

Redox Biology ◽

10.1016/j.redox.2021.101960 ◽

2021 ◽

pp. 101960

Author(s):

Lei-Lei Ma ◽

Zhi-Wen Ding ◽

Pei-Pei Yin ◽

Jian Wu ◽

Kai Hu ◽

...

Keyword(s):

Reperfusion Injury ◽

Myocardial Ischaemia ◽

Ischaemia Reperfusion Injury ◽

Ischaemia Reperfusion

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Nitrite and myocardial ischaemia reperfusion injury. Where are we now?

Pharmacology & Therapeutics ◽

10.1016/j.pharmthera.2021.107819 ◽

2021 ◽

Vol 223 ◽

pp. 107819

Author(s):

Kayleigh Griffiths ◽

Jordan J. Lee ◽

Michael P. Frenneaux ◽

Martin Feelisch ◽

Melanie Madhani

Keyword(s):

Reperfusion Injury ◽

Myocardial Ischaemia ◽

Ischaemia Reperfusion Injury ◽

Ischaemia Reperfusion

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Hypertrophic Preconditioning Attenuates Myocardial Ischaemia‐Reperfusion Injury by Modulating SIRT3‐SOD2‐mROS‐Dependent Autophagy

Cell Proliferation ◽

10.1111/cpr.13051 ◽

2021 ◽

Author(s):

Lei‐Lei Ma ◽

Fei‐Juan Kong ◽

Zheng Dong ◽

Kai‐Yue Xin ◽

Xing‐Xu Wang ◽

...

Keyword(s):

Reperfusion Injury ◽

Myocardial Ischaemia ◽

Ischaemia Reperfusion Injury ◽

Ischaemia Reperfusion

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Cardioprotective effects of melatonin against myocardial ischaemia/reperfusion injury: Activation of AMPK/Nrf2 pathway

Journal of Cellular and Molecular Medicine ◽

10.1111/jcmm.16691 ◽

2021 ◽

Author(s):

Chennian Xu ◽

Jian Wang ◽

Zhenge Fan ◽

Shuang Zhang ◽

Rui Qiao ◽

...

Keyword(s):

Reperfusion Injury ◽

Myocardial Ischaemia ◽

Ischaemia Reperfusion Injury ◽

Nrf2 Pathway ◽

Ischaemia Reperfusion ◽

Cardioprotective Effects

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