scholarly journals The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
K. I. Watt ◽  
B. J. Turner ◽  
A. Hagg ◽  
X. Zhang ◽  
J. R. Davey ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibre ◽  
Hippo Pathway ◽  
Skeletal Muscle Fibre ◽  
Muscle Fibre Size ◽  
Fibre Size ◽  
The Hippo Pathway

Skeletal muscle fibre size adaptation to an eight-week swimming programme

1980 ◽  
Vol 44 (2) ◽  
pp. 161-165 ◽  
Author(s):  
J. -M. Lavoie ◽  
A. W. Taylor ◽  
R. R. Montpetit
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibre ◽  
Skeletal Muscle Fibre ◽  
Muscle Fibre Size ◽  
Fibre Size

scholarly journals Using AAV vectors expressing the β2-adrenoceptor or associated Gα proteins to modulate skeletal muscle mass and muscle fibre size

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Adam Hagg ◽  
Timothy D. Colgan ◽  
Rachel E. Thomson ◽  
Hongwei Qian ◽  
Gordon S. Lynch ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibre ◽  
Muscle Mass ◽  
Skeletal Muscle Mass ◽  
Muscle Fibre Size ◽  
Fibre Size

scholarly journals Overcoming nature’s paradox in skeletal muscle to optimise animal production

2019 ◽  
Vol 59 (11) ◽  
pp. 1957
Author(s):  
Gordon S. Lynch ◽  
René Koopman
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibre ◽  
Oxidative Capacity ◽  
Animal Production ◽  
Food Sources ◽  
Muscle Size ◽  
Meat Production ◽  
Endurance Capacity ◽  
Muscle Fibre Size ◽  
Fibre Size

Nature’s paradox in skeletal muscle describes the seemingly mutually exclusive relationship between muscle fibre size and oxidative capacity. In mammals, there is a constraint on the size at which mitochondria-rich, high O2-dependent oxidative fibres can attain before they become anoxic or adapt to a glycolytic phenotype, being less reliant on O2. This implies that a muscle fibre can hypertrophy at the expense of its endurance capacity. Adaptations to activity (exercise) generally obey this relationship, with optimal muscle endurance generally being linked to an enhanced proportion of small, slow oxidative fibres and muscle strength (force and/or power) being linked to an enhanced proportion of large, fast glycolytic fibres. This relationship generally constrains not only the physiological limits of performance (e.g. speed and endurance), but also the capacity to manipulate muscle attributes such as fibre size and composition, with important relevance to the livestock and aquaculture industries for producing specific muscle traits such as (flesh) quality, texture and taste. Highly glycolytic (white) muscles have different traits than do highly oxidative (red) muscles and so the ability to manipulate muscle attributes to produce flesh with specific traits has important implications for optimising meat production and quality. Understanding the biological regulation of muscle size, and phenotype and the capacity to manipulate signalling pathways to produce specific attributes, has important implications for promoting ethically sustainable and profitable commercial livestock and aquaculture practices and for developing alternative food sources, including ‘laboratory meat’ or ‘clean meat’. This review describes the exciting potential of manipulating muscle attributes relevant to animal production, through traditional nutritional and pharmacological approaches and through viral-mediated strategies that could theoretically push the limits of muscle fibre growth, adaptation and plasticity.

Skeletal muscle fibre swelling contributes to force depression in rats and humans: a mechanically-skinned fibre study

2019 ◽  
Vol 40 (3-4) ◽  
pp. 343-351 ◽  
Author(s):  
Daiki Watanabe ◽  
Travis L. Dutka ◽  
Cedric R. Lamboley ◽  
Graham D. Lamb
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibre ◽  
Skeletal Muscle Fibre ◽  
Force Depression ◽  
Skinned Fibre

Adrenaline-mediated glycogenolysis in different skeletal muscle fibre types in the anaesthetized rat

1989 ◽  
Vol 136 (2) ◽  
pp. 229-233 ◽  
Author(s):  
J. JENSEN ◽  
H. A. DAHL ◽  
P. K. OPSTAD
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibre ◽  
Skeletal Muscle Fibre ◽  
Fibre Types ◽  
Muscle Fibre Types ◽  
Anaesthetized Rat

scholarly journals McArdle disease does not affect skeletal muscle fibre type profiles in humans

Biology Open ◽  
2014 ◽  
Vol 3 (12) ◽  
pp. 1224-1227 ◽  
Author(s):  
T. A. Kohn ◽  
T. D. Noakes ◽  
D. E. Rae ◽  
J. C. Rubio ◽  
A. Santalla ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibre ◽  
Fibre Type ◽  
Skeletal Muscle Fibre ◽  
Muscle Fibre Type ◽  
Mcardle Disease

scholarly journals Comparative skeletal muscle fibre morphometry among wild birds with different locomotor behaviour

1998 ◽  
Vol 192 (2) ◽  
pp. 211-222 ◽  
Author(s):  
J. R. TORRELLA ◽  
V. FOUCES ◽  
J. PALOMEQUE ◽  
G. VISCOR
Keyword(s):  
Skeletal Muscle ◽  
Muscle Fibre ◽  
Skeletal Muscle Fibre ◽  
Wild Birds ◽  
Locomotor Behaviour
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