oxidative capacity
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2023 ◽  
Vol 83 ◽  
Author(s):  
F. Gul ◽  
B. Ahmad ◽  
S. Afzal ◽  
A. Ullah ◽  
S. Khan ◽  
...  

Abstract The supplementation of Selenium-enriched probiotics is effective in reducing oxidative stress and maintaining meat quality stability in broiler chicken especially under heat stress. An experimental study was conducted to perform Comparative analysis of Selenium yeast with inorganic Se in broilers under heat stress. A total of 120 broilers chicks of one day were assigned to 4 groups each consisting 30 chicks fed on same basal diet but different selenium sources. The basal diet of group D1 was not supplemented with Se source (Negative control), group D2 basal diet was supplemented with inorganic selenium (Sodium selenite 0.22mg/Kg starter phase and 0.15mg/Kg finisher phase), group D3 basal diet was supplemented with commercially available organic selenium (Seleno-methionine 0.22mg/Kg starter phase and 0.15mg/Kg finisher phase) and group D4 basal diet was supplemented with self-developed organic selenium (Se-enriched yeast 0.22mg/Kg starter phase and 0.15mg/Kg finisher phase). The performance parameters i.e. feed intake (FI), live body weight (BW) and FCR were not significantly (p>0.05) effected by selenium supplementation in the starter phase but were significantly (p<0.05) effected in the finisher phase. Selenium supplementation significantly (p<0.05) effected serum Se level in different supplemented groups. Higher serum Se value (58.20±0.06) was recorded in D4 group. Similarly significantly lower selenium value was recorded for D4 and higher was recorded for D1 (11.36±0.08). However lower serum Paraoxonase (PON) value was recorded for D4 (13.24±0.01) and higher for D1 (13.33±0.03). Comparatively self-developed Se enriched yeast increased the Se accumulation and improved antioxidant system. Glutathione peroxidase (GPx) was found higher in D4 (12.333±0.03) followed by D3, D2 and D1 respectively. Whereas superoxide dismutase (SOD) was significantly lower (p<0.05) in D4 (0.1437±0.003) followed by D3 (0.1457±0.002). Selenium supplementation increased the bird’s survival rate. Birds fed on Se enriched yeast showed higher Se deposition and better antioxidant capacity as compared to other sources of selenium. Se-enriched yeast displayed an improved result on Se deposition in tissues, and oxidative capacity, meat tenderness and immune response level as compared to other sources of selenium.


2022 ◽  
Vol 8 (1) ◽  
pp. 46-56
Author(s):  
Yasemin Ertaş Öztürk ◽  
Duygu Ağagündüz

It was aimed to evaluate the effects of different ingredi-ents on total antioxidant sta-tus (TAS) and total oxidant status (TOS) of the brewed Brazil mild roasted coffee. Sugar, sucralose, butter, co-conut-oil, animal and plant-based milk types were add-ed and milk types&sweeteners were combined separately. TAS and TOS were measured and oxidative stress indice (OSI) was calculated. TAS value of coffee with whole milk was the highest among all coffee types. TOS values of coffee with soy milk, with soy milk+sugar and soy milk+sucralose were lower than all other coffee types. When compared to OSI val-ues, coffee with soy milk, with soy milk+sugar and soy milk+sucralose had the lowest OSI values among all coffee types. Moreover, ad-dition of coconut-oil to cof-fee samples increased the TOS and OSI values of cof-fees. While the TOS and OSI of the sugar and su-cralose addition were found higher in comparison to plain coffee; TOS and OSI of the sucralose addition was lower than those sugar combinations. In conclu-sion, the OSI of the coffee may change depending on the alterations of chemical structures and nutritional matrices by the added in-gredients. The addition of soy milk or sucralose in-stead of sugar or whole cow milk instead of oil-based ingredients could be a promising strategy of reduc-ing the oxidative capacity.


Author(s):  
Zsuzsanna Gaál ◽  
János Fodor ◽  
Attila Oláh ◽  
Tamás Radovits ◽  
Béla Merkely ◽  
...  

AbstractMaking benefit from the epigenetic effects of environmental factors such as physical activity may result in a considerable improvement in the prevention of chronic civilization diseases. In our chronic swimming rat model, the expression levels of such microRNAs were characterized, that are involved in skeletal muscle differentiation, hypertrophy and fine-tuning of metabolism, which processes are influenced by chronic endurance training, contributing to the metabolic adaptation of skeletal muscle during physical activity. After chronic swimming, the level of miR-128a increased significantly in EDL muscles, which may influence metabolic adaptation and stress response as well. In SOL, the expression level of miR-15b and miR-451 decreased significantly after chronic swimming, which changes are opposite to their previously described increment in insulin resistant skeletal muscle. MiR-451 also targets PGC-1α mRNA, whiches expression level significantly increased in SOL muscles, resulting in enhanced biogenesis and oxidative capacity of mitochondria. In summary, the microRNA expression changes that were observed during our experiments suggest that chronic swim training contributes to a beneficial metabolic profile of skeletal muscle.


2021 ◽  
Vol 8 ◽  
Author(s):  
Elise S. Droste ◽  
Alex R. Baker ◽  
Chan Yodle ◽  
Andrew Smith ◽  
Laurens Ganzeveld

Iodine affects the radiative budget and the oxidative capacity of the atmosphere and is consequently involved in important climate feedbacks. A fraction of the iodine emitted by oceans ends up in aerosols, where complex halogen chemistry regulates the recycling of iodine to the gas-phase where it effectively destroys ozone. The iodine speciation and major ion composition of aerosol samples collected during four cruises in the East and West Pacific and Indian Oceans was studied to understand the influences on iodine’s gas-aerosol phase recycling. A significant inverse relationship exists between iodide (I–) and iodate (IO3–) proportions in both fine and coarse mode aerosols, with a relatively constant soluble organic iodine (SOI) fraction of 19.8% (median) for fine and coarse mode samples of all cruises combined. Consistent with previous work on the Atlantic Ocean, this work further provides observational support that IO3– reduction is attributed to aerosol acidity, which is associated to smaller aerosol particles and air masses that have been influenced by anthropogenic emissions. Significant correlations are found between SOI and I–, which supports hypotheses that SOI may be a source for I–. This data contributes to a growing observational dataset on aerosol iodine speciation and provides evidence for relatively constant proportions of iodine species in unpolluted marine aerosols. Future development in our understanding of iodine speciation depends on aerosol pH measurements and unravelling the complex composition of SOI in aerosols.


Author(s):  
Anders Gudiksen ◽  
Albina Qoqaj ◽  
Stine Ringholm ◽  
Jørgen Wojtaszewski ◽  
Peter Plomgaard ◽  
...  

Abstract Growing old is patently among the most prominent risk factors for lifestyle related diseases and deterioration in physical performance. Aging in particular affects mitochondrial homeostasis and maintaining a well-functioning mitochondrial pool is imperative in order to avoid age-associated metabolic decline. White adipose tissue (WAT) is a key organ in energy balance and impaired mitochondrial function in adipocytes has been associated with increased low-grade inflammation, altered metabolism, excessive ROS production and an accelerated aging phenotype. Exercise training improves mitochondrial health but whether lifelong exercise training can sufficiently maintain WAT mitochondrial function is currently unknown. Therefore, to dissect the role and dose-dependence of lifelong exercise training on aging WAT metabolic parameters and mitochondrial function, young and older untrained, as well as moderately and highly exercise trained older male subjects were recruited and abdominal subcutaneous (s)WAT biopsies and venous blood samples were obtained to measure mitochondrial function and key metabolic factors in WAT and plasma. Mitochondrial intrinsic respiratory capacity was lower in sWAT from older than in young subjects. In spite of this, maximal mitochondrial respiration per wet weight, markers of oxidative capacity, and mitophagic capacity were increased in sWAT from lifelong highly exercise trained than all other groups. Furthermore, ROS emission was generally lower in sWAT from lifelong highly exercise trained than older untrained subjects. Taken together, aging reduces intrinsic mitochondrial respiration in human sWAT, but lifelong high volume exercise training increases oxidative capacity by increasing mitochondrial volume likely contributing to healthy aging.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 685-686
Author(s):  
Fei Zhao ◽  
Machiko Tomita ◽  
Anirban Dutta

Abstract Objective Obesity and physical activity are two major factors affecting aerobic performance in older adults. The underlying mechanisms of the causes are still unknown. Oxidative capacity, muscles’ maximal capacity to utilize oxygen, is a part of aerobic performance. Muscle oxygen level (SmO2), a measure of oxidative capacity, reflects the balance between oxygen delivery and oxygen demand. When oxygen delivery surpasses oxygen demand, SmO2 increases, which indicates higher oxidative capacity. This study aimed to identify the influence of obesity and physical activity level on SmO2 changes during and after short exercise. Methods This is a cross-sectional study. SmO2 changes during and after a bilateral heel-raise (BHR) test were measured in 60 community-dwelling older adults (≥ 60 years old) in four groups: inactive obese, active obese, inactive non-obese, and active non-obese. Inactive is defined as performing less than 150 minutes/week moderate-intensity activity. Results The inactive obese group took a longer time for SmO2 drop during the BHR test, had a lower SmO2 level at the end, and recovered slower after the test than all other groups. Especially, compared with the active non-obese group, this group exhibited significantly poorer SmO2 recovery one minute after the test, 5.3% less (p=.036). The active obese group’s oxidative capacity was similar to the inactive non-obese group, although lower than the active non-obese group. Discussion To prevent physical decline in older adults with obesity, regular exercise has been recommended. This study substantiated this from a hemodynamics viewpoint. Older adults with obesity need 150+ minutes/week moderate-intensity exercise.


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