scholarly journals An ensemble of neural networks provides expert-level prenatal detection of complex congenital heart disease

Author(s):  
Rima Arnaout ◽  
Lara Curran ◽  
Yili Zhao ◽  
Jami C. Levine ◽  
Erin Chinn ◽  
...  
2021 ◽  
Vol 12 (6) ◽  
pp. 754-759
Author(s):  
William N. Evans ◽  
Ruben J. Acherman ◽  
Michael L. Ciccolo ◽  
Juan Lehoux ◽  
Alvaro Galindo ◽  
...  

Objective We reviewed our center's prenatal detection and surgical experience with high-risk, 2-ventricle patients, with complex congenital heart disease that underwent stage-1 hybrid palliation. Methods We retrospectively identified those born between March 2008 and March 2021 with 2-ventricle hearts, complex congenital cardiovascular malformations, and ductal-dependent systemic circulation that underwent stage-1 hybrid palliation consisting of surgical bilateral pulmonary artery banding and interventional catheterization placed ductus arteriosus stents. Results We identified 30 patients. Of the 30, 19 (63%) were male. For the 30, median gestational age was 35 weeks (29-39 weeks), and median birth weight was 2.2 kg (0.6-4.5 kg). Of the 30, 1 was transferred from an adjacent state, and 29 were born in Nevada. Of the 29 born in Nevada, overall statewide prenatal detection was 18 of 29 (62%); however, for 2008 to 2011 the prenatal detection rate was 3 of 10 (30%) and 15 of 19 (79%) for 2012 to 2021, P = .03. For the last 5 years, prenatal detection for Nevada-born patients was 8 of 8 (100%). Two full-term newborns, without a prenatal diagnosis, presented postnatally in extremis. For the 30 patients, there were 0 stage-1 hybrid palliation mortalities, 1 subsequent repair mortality, and 3 late nonsurgical deaths. Conclusions Stage-1 hybrid palliation may result in excellent surgical outcomes for high-risk, 2-ventricle patients. Additionally, high rates of population-wide prenatal detection are possible for high-risk congenital heart disease, allowing prenatal planning and possibly reducing postnatal extremis presentations.


2019 ◽  
Vol 16 (3) ◽  
pp. 187-191
Author(s):  
T.V. Rogova ◽  
A.I. Kim ◽  
A.V. Sobolev ◽  
S.A. Aleksandrova ◽  
E.V. Kholmanskaya ◽  
...  

2009 ◽  
Vol 11 (4) ◽  
pp. 291-297 ◽  
Author(s):  
Alison Knauth Meadows ◽  
Valerie Bosco ◽  
Elizabeth Tong ◽  
Susan Fernandes ◽  
Arwa Saidi

2017 ◽  
Vol 9 (3) ◽  
pp. 364-367
Author(s):  
Abid Iqbal ◽  
Sabarinath Menon ◽  
Baiju S. Dharan ◽  
Kapilamoorthy Tirur Raman ◽  
Jayakumar Karunakaran

Submitral aneurysms are rare clinical entities occurring predominantly in young adults of African descent. A host of etiologies have been proposed for this entity. We present a unique case of submitral aneurysm which developed after pulmonary artery banding in a three-year-old girl with complex congenital heart disease. The aneurysmal sac was burrowing into the interatrial septum.


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