scholarly journals Optimized beam shaping assembly for a 2.1-MeV proton-accelerator-based neutron source for boron neutron capture therapy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Pablo Torres-Sánchez ◽  
Ignacio Porras ◽  
Nataliya Ramos-Chernenko ◽  
Fernando Arias de Saavedra ◽  
Javier Praena

AbstractBoron Neutron Capture Therapy (BNCT) is facing a new era where different projects based on accelerators instead of reactors are under development. The new facilities can be placed at hospitals and will increase the number of clinical trials. The therapeutic effect of BNCT can be improved if a optimized epithermal neutron spectrum is obtained, for which the beam shape assembly is a key ingredient. In this paper we propose an optimal beam shaping assembly suited for an affordable low energy accelerator. The beam obtained with the device proposed accomplishes all the IAEA recommendations for proton energies between 2.0 and 2.1 MeV. In addition, there is an overall improvement of the figures of merit with respect to BNCT facilities and previous proposals of new accelerator-based facilities.

2010 ◽  
Author(s):  
Alejandro A. Burlon ◽  
Santiago Girola ◽  
Alejandro A. Valda ◽  
Daniel M. Minsky ◽  
Andrés J. Kreiner ◽  
...  

2017 ◽  
Vol 80 (1) ◽  
pp. 60-66 ◽  
Author(s):  
L. Zaidi ◽  
E. A. Kashaeva ◽  
S. I. Lezhnin ◽  
G. N. Malyshkin ◽  
S. I. Samarin ◽  
...  

2018 ◽  
Vol 35 (3) ◽  
pp. 183-186
Author(s):  
Arief Fauzi ◽  
Afifah Hana Tsurayya ◽  
Ahmad Faisal Harish ◽  
Gede Sutresna Wijaya

A design of beam shaping assembly (BSA) installed on cyclotron 30 MeV model neutron source for boron neutron capture therapy (BNCT) has been optimized using simulator software of Monte Carlo N-Particle Extended (MCNPX). The Beryllium target with thickness of 0.55 cm is simulated to be bombarded with 30 MeV of proton beam. In this design, the parameter regarding beam characteristics for BNCT treatment has been improved, which is ratio of fast neutron dose and epithermal neutron flux. TiF3 is replaced to 30 cm of 27Al as moderator, and 1.5 cm of 32S is combined with 28 cm of 60Ni as neutron filter. Eventually, this design produces epithermal neutron flux of 2.33 × 109, ratio between fast neutron dose and epithermal neutron flux of 2.12 × 10-13,ratio between gamma dose and epithermal neutron flux of 1.00 × 10-13, ratio between thermal neutron flux and epithermal neutron flux is 0.047, and ration between particle current and total neutron flux is 0.56.


2003 ◽  
Author(s):  
J. Vujic ◽  
E. Greenspan ◽  
W.E. Kastenber ◽  
Y. Karni ◽  
D. Regev ◽  
...  

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