scholarly journals A deep learning model for detection of cervical spinal cord compression in MRI scans

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zamir Merali ◽  
Justin Z. Wang ◽  
Jetan H. Badhiwala ◽  
Christopher D. Witiw ◽  
Jefferson R. Wilson ◽  
...  

AbstractMagnetic Resonance Imaging (MRI) evidence of spinal cord compression plays a central role in the diagnosis of degenerative cervical myelopathy (DCM). There is growing recognition that deep learning models may assist in addressing the increasing volume of medical imaging data and provide initial interpretation of images gathered in a primary-care setting. We aimed to develop and validate a deep learning model for detection of cervical spinal cord compression in MRI scans. Patients undergoing surgery for DCM as a part of the AO Spine CSM-NA or CSM-I prospective cohort studies were included in our study. Patients were divided into a training/validation or holdout dataset. Images were labelled by two specialist physicians. We trained a deep convolutional neural network using images from the training/validation dataset and assessed model performance on the holdout dataset. The training/validation cohort included 201 patients with 6588 images and the holdout dataset included 88 patients with 2991 images. On the holdout dataset the deep learning model achieved an overall AUC of 0.94, sensitivity of 0.88, specificity of 0.89, and f1-score of 0.82. This model could improve the efficiency and objectivity of the interpretation of cervical spine MRI scans.

2017 ◽  
Vol 46 (8) ◽  
pp. 1125-1130 ◽  
Author(s):  
Ryunosuke Fukushi ◽  
Makoto Emori ◽  
Noriyuki Iesato ◽  
Masanobu Kano ◽  
Toshihiko Yamashita

2014 ◽  
Vol 36 (7) ◽  
pp. 634-636 ◽  
Author(s):  
Po-Cheng Hung ◽  
Huei-Shyong Wang ◽  
Cheng-Hsun Chiu ◽  
Alex M.-C. Wong

2015 ◽  
Vol 2 (5) ◽  
Author(s):  
Eshraga A. Ezaldeen ◽  
Raif Mohamed Ahmed ◽  
El Sammani Wadella ◽  
Nadia El Dawi ◽  
Ahmed Hassan Fahal

2019 ◽  
Vol 128 ◽  
pp. e782-e786
Author(s):  
Jing Cao ◽  
Yilin Liu ◽  
Yuqiang Wang ◽  
Liang Zhao ◽  
Weidong Wang ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Nooraldin Merza ◽  
Ahmed Taha ◽  
John Lung ◽  
Anthony W. Benderman ◽  
Stephen E. Wright

Immunoglobulin G4-related disease (IgG4-RD) is known for forming soft tissue mass lesions that may have compressive effects. It is an extremely rare disease that most frequently affects the pancreas causing autoimmune pancreatitis. It can also affect the gallbladder, salivary glands, and lacrimal glands causing respective organ-specific complications. In our report, we describe an IgG4-RD case that affected the spinal cord. A 60-year-old female presented with cervical spinal cord compression caused by IgG4-RD leading to several neurological deficits. Pathological examination of the excisional biopsy of the mass revealed dense lymphoplasmacytic cells infiltration and stromal fibrosis with IgG4 and plasma cells. The patient showed a dramatic response to the administration of systemic steroids with almost resolution of her neurological symptoms. This case highlights the first case in literature for IgG4-RD of the extradural tissue causing spinal compression. Hereby, we also demonstrate the dramatic response of IgG4-RD to the administration of systemic steroids as the patient had no recurrence after 5 years of close follow-up, the longest reported period of follow-up reported in the literature to date.


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