scholarly journals Author Correction: Cochlear SGN neurons elevate pain thresholds in response to music

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
R. I. M. Dunbar ◽  
Eiluned Pearce ◽  
Bronwyn Tarr ◽  
Adarsh Makdani ◽  
Joshua Bamford ◽  
...  
Keyword(s):  
Pain Thresholds

scholarly journals High concurrent validity between digital and analogue algometers to measure pressure pain thresholds in healthy participants and people with migraine: a cross-sectional study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
René F. Castien ◽  
Michel W. Coppieters ◽  
Tom S. C. Durge ◽  
Gwendolyne G. M. Scholten-Peeters
Keyword(s):  
Concurrent Validity ◽  
Tibialis Anterior Muscle ◽  
Intraclass Correlation ◽  
Cephalic Region ◽  
Limits Of Agreement ◽  
Temporal Muscle ◽  
Pain Thresholds ◽  
Pressure Pain ◽  
Pressure Pain Thresholds ◽  
Healthy Participants

Abstract Background Pressure pain thresholds (PPTs) are commonly assessed to quantify mechanical sensitivity in various conditions, including migraine. Digital and analogue algometers are used, but the concurrent validity between these algometers is unknown. Therefore, we assessed the concurrent validity between a digital and analogue algometer to determine PPTs in healthy participants and people with migraine. Methods Twenty-six healthy participants and twenty-nine people with migraine participated in the study. PPTs were measured interictally and bilaterally at the cephalic region (temporal muscle, C1 paraspinal muscles, and trapezius muscle) and extra-cephalic region (extensor carpi radialis muscle and tibialis anterior muscle). PPTs were first determined with a digital algometer, followed by an analogue algometer. Intraclass correlation coefficients (ICC3.1) and limits of agreement were calculated to quantify concurrent validity. Results The concurrent validity between algometers in both groups was moderate to excellent (ICC3.1 ranged from 0.82 to 0.99, with 95%CI: 0.65 to 0.99). Although PPTs measured with the analogue algometer were higher at most locations in both groups (p < 0.05), the mean differences between both devices were less than 18.3 kPa. The variation in methods, such as a hand-held switch (digital algometer) versus verbal commands (analogue algometer) to indicate when the threshold was reached, may explain these differences in scores. The limits of agreement varied per location and between healthy participants and people with migraine. Conclusion The concurrent validity between the digital and analogue algometer is excellent in healthy participants and moderate in people with migraine. Both types of algometer are well-suited for research and clinical practice but are not exchangeable within a study or patient follow-up.

The tolerance to stretch is linked with endogenous modulation of pain

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Morten Pallisgaard Støve ◽  
Rogerio Pessoto Hirata ◽  
Thorvaldur Skuli Palsson
Keyword(s):  
Range Of Motion ◽  
Pain Sensitivity ◽  
Cold Pressor Test ◽  
Cold Pressor ◽  
Static Stretch ◽  
Pain Thresholds ◽  
Pressure Pain ◽  
Pressor Test ◽  
Pressure Pain Thresholds ◽  
Exercise Induced

Abstract Objectives The effect of stretching on joint range of motion is well documented, and although sensory perception has significance for changes in the tolerance to stretch following stretching the underlining mechanisms responsible for these changes is insufficiently understood. The aim of this study was to examine the influence of endogenous pain inhibitory mechanisms on stretch tolerance and to investigate the relationship between range of motion and changes in pain sensitivity. Methods Nineteen healthy males participated in this randomized, repeated-measures crossover study, conducted on 2 separate days. Knee extension range of motion, passive resistive torque, and pressure pain thresholds were recorded before, after, and 10 min after each of four experimental conditions; (i) Exercise-induced hypoalgesia, (ii) two bouts of static stretching, (iii) resting, and (iv) a remote, painful stimulus induced by the cold pressor test. Results Exercise-induced hypoalgesia and cold pressor test caused an increase in range of motion (p<0.034) and pressure pain thresholds (p<0.027). Moderate correlations in pressure pain thresholds were found between exercise-induced hypoalgesia and static stretch (Rho>0.507, p=0.01) and exercise-induced hypoalgesia and the cold pressor test (Rho=0.562, p=0.01). A weak correlation in pressure pain thresholds and changes in range of motion were found following the cold pressor test (Rho=0.460, p=0.047). However, a potential carryover hypoalgesic effect may have affected the results of the static stretch. Conclusions These results suggest that stretch tolerance may be linked with endogenous modulation of pain. Present results suggest, that stretch tolerance may merely be a marker for pain sensitivity which may have clinical significance given that stretching is often prescribed in the rehabilitation of different musculoskeletal pain conditions where reduced endogenous pain inhibition is frequently seen.

Mode of action of cupping—Local metabolism and pain thresholds in neck pain patients and healthy subjects

2014 ◽  
Vol 22 (1) ◽  
pp. 148-158 ◽  
Author(s):  
M. Emerich ◽  
M. Braeunig ◽  
H.W. Clement ◽  
R. Lüdtke ◽  
R. Huber
Keyword(s):  
Neck Pain ◽  
Mode Of Action ◽  
Healthy Subjects ◽  
Pain Thresholds ◽  
Pain Patients ◽  
Local Metabolism

scholarly journals Pressure pain thresholds fluctuate with, but do not usefully predict, the clinical course of painful temporomandibular disorder

Pain ◽  
2014 ◽  
Vol 155 (10) ◽  
pp. 2134-2143 ◽  
Author(s):  
Gary D. Slade ◽  
Anne E. Sanders ◽  
Richard Ohrbach ◽  
Roger B. Fillingim ◽  
Ron Dubner ◽  
...  
Keyword(s):  
Clinical Course ◽  
Temporomandibular Disorder ◽  
Pain Thresholds ◽  
Pressure Pain ◽  
Pressure Pain Thresholds

Effects of extremely low frequency magnetic fields on pain thresholds in mice: roles of melatonin and opioids

2000 ◽  
Vol 20 (4) ◽  
pp. 259-264 ◽  
Author(s):  
J. H. Jeong ◽  
K. B. Choi ◽  
B. C. Yi ◽  
C. H. Chun ◽  
K.-Y. Sung ◽  
...  
Keyword(s):  
Magnetic Fields ◽  
Low Frequency ◽  
Pain Thresholds ◽  
Extremely Low Frequency

scholarly journals The effects of anger and sadness on clinical pain reports and experimentally-induced pain thresholds in women with and without fibromyalgia

2010 ◽  
Vol 62 (10) ◽  
pp. 1370-1376 ◽  
Author(s):  
Henriët van Middendorp ◽  
Mark A. Lumley ◽  
Johannes W. G. Jacobs ◽  
Johannes W. J. Bijlsma ◽  
Rinie Geenen
Keyword(s):  
Pain Thresholds ◽  
Clinical Pain ◽  
Pain Reports ◽  
Experimentally Induced

Somatosensory and trophic findings in the referred pain area in patients with kidney stone disease

2013 ◽  
Vol 4 (3) ◽  
pp. 165-170 ◽  
Author(s):  
Katja Venborg Pedersen ◽  
Asbjørn Mohr Drewes ◽  
Ole Graumann ◽  
Susanne Sloth Osther ◽  
Anne Estrup Olesen ◽  
...  
Keyword(s):  
Ct Scan ◽  
Kidney Stone ◽  
Stone Disease ◽  
Referred Pain ◽  
Lateral Side ◽  
Pain Thresholds ◽  
Kidney Stone Disease ◽  
Trophic Changes ◽  
Electrical Stimuli ◽  
Pain Area

AbstractBackground and purposeVisceral and somatic afferents activate the same neuronal structures in the central nervous system. Assessing somatosensory function and trophic changes in the referred pain area may therefore indirectly increase information on mechanisms involved in painful visceral diseases. The aim of this study was to evaluate the sensory and trophic changes in the flank corresponding to the referred pain area in patients with kidney stone disease.MethodsA total of 24 patients with unilateral pain-causing kidney stone disease were studied before and after endoscopic percutaneous kidney stone surgery. Trophic changes and sensitivity on the affected and on the contra-lateral side in the pain free period were investigated. For this purpose we used standardized experimental sensory testing including pressure stimulation and electrical (single and repeated) skin stimulation. Five repeated stimuli were used to investigate temporal summation (increased responses to repeated stimuli). To investigate trophic changes ultrasound as well as CT-scan was used, since the latter is considered more precise for exact tissue layer measurements.ResultsThe pain tolerance thresholds to pressure and pain thresholds to electrical stimulation were not significantly different on the two sides (all P>0.1). After surgery no significant alterations in sensitivity were detected, but there was a tendency to higher pain thresholds to electrical stimuli on the affected side (single stimuli P=0.06; repeated stimuli P=0.09). No trophic changes were observed (all P>0.3), and there were no relations between the pain thresholds or trophic findings and the number of colics (all P >0.08).ConclusionIn patients with unilateral pain-causing kidney stone disease the pain to experimental pressure and electrical stimuli were comparable on the affected and contra-lateral side. For the first time a CT-scan was used to evaluate tissue thickness in the referred pain area. No trophic changes were seen in the muscle or subcutaneous tissue at the affected side, and there were no correlations between the pain thresholds or trophic findings and the patients history of number of colics. After the operation no significant alterations in sensitivity were detected.ImplicationsThis study could not confirm previous studies showing referred hyperalgesia in the skin and trophic changes in the referred pain area to painful visceral disease. Differences in the pain intensity/duration between different diseases and hence the corresponding central neuronal changes may explain the negative findings in the present study.

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