scholarly journals Humanized bone marrow, liver and thymus (huBLT) mouse model of Kaposi's sarcoma–associated herpes virus (KSHV) infection

2014 ◽  
Vol 7 (9) ◽  
pp. 269-269
Keyword(s):  
Bone Marrow ◽  
Mouse Model ◽  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Kshv Infection ◽  
Herpès Virus

Blood Dendritic Cells From Myeloma Patients Are Not Infected With Kaposi's Sarcoma-Associated Herpesvirus (KSHV/HHV-8)

Blood ◽  
1998 ◽  
Vol 92 (2) ◽  
pp. 402-404 ◽  
Author(s):  
Qing Yi ◽  
Marianne Ekman ◽  
Doina Anton ◽  
Susanne Bergenbrant ◽  
Anders Österborg ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Dendritic Cells ◽  
Cell Lines ◽  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Bone Marrow Cells ◽  
Kaposi’S Sarcoma ◽  
Myeloma Cell ◽  
Herpès Virus ◽  
Marrow Cells

In recent studies, the sequence of Kaposi's sarcoma-associated herpes virus (KSHV) or human herpes virus-8 (HHV-8) was detected in dendritic cells (DC) of patients with multiple myeloma (MM). A concern was raised whether there is an causal association between the viral infection and development of these tumors. In the present study, we have examined DC generated from blood adherent cells from 8 Swedish MM patients at different clinical stages and 2 patients with monoclonal gammopathy of undetermined significance. In addition, 6 myeloma cell lines and bone marrow cells from 2 MM patients were also studied. By polymerase chain reaction (PCR), including nested PCR, no virus DNA was demonstrable in the patients' DC or in myeloma cell lines or fresh bone marrow cells. Moreover, no antibody against KSHV was found in the serum of these 10 patients. Thus, our results indicate that blood-derived DC of MM patients in Sweden usually are not infected with KSHV/HHV-8. This study also suggests that KSHV/HHV-8 is not regularly associated with MM and consequently does not play a primary role in the pathogenesis of these tumors.

Blood Dendritic Cells From Myeloma Patients Are Not Infected With Kaposi's Sarcoma-Associated Herpesvirus (KSHV/HHV-8)

Blood ◽  
1998 ◽  
Vol 92 (2) ◽  
pp. 402-404 ◽  
Author(s):  
Qing Yi ◽  
Marianne Ekman ◽  
Doina Anton ◽  
Susanne Bergenbrant ◽  
Anders Österborg ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Dendritic Cells ◽  
Cell Lines ◽  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Bone Marrow Cells ◽  
Kaposi’S Sarcoma ◽  
Myeloma Cell ◽  
Herpès Virus ◽  
Marrow Cells

Abstract In recent studies, the sequence of Kaposi's sarcoma-associated herpes virus (KSHV) or human herpes virus-8 (HHV-8) was detected in dendritic cells (DC) of patients with multiple myeloma (MM). A concern was raised whether there is an causal association between the viral infection and development of these tumors. In the present study, we have examined DC generated from blood adherent cells from 8 Swedish MM patients at different clinical stages and 2 patients with monoclonal gammopathy of undetermined significance. In addition, 6 myeloma cell lines and bone marrow cells from 2 MM patients were also studied. By polymerase chain reaction (PCR), including nested PCR, no virus DNA was demonstrable in the patients' DC or in myeloma cell lines or fresh bone marrow cells. Moreover, no antibody against KSHV was found in the serum of these 10 patients. Thus, our results indicate that blood-derived DC of MM patients in Sweden usually are not infected with KSHV/HHV-8. This study also suggests that KSHV/HHV-8 is not regularly associated with MM and consequently does not play a primary role in the pathogenesis of these tumors.

MOLECULAR DETECTION OF KAPOSI’S SARCOMA ASSOCIATED VIRUS (HUMAN HERPES VIRUS 8) IN SINO-NASAL CARCINOMA TISSUES

2020 ◽  
Vol 23 (04) ◽  
pp. 286-297
Author(s):  
Hind Hamed Shaker ◽  
Luma Amer Yasir ◽  
Ausama Abed-Alkadum Alajeely ◽  
Saad Hasan Mohammed Ali ◽  
Shakir H. Mohammed Al-Alwany
Keyword(s):  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Molecular Detection ◽  
Kaposi’S Sarcoma ◽  
Human Herpes ◽  
Human Herpes Virus 8 ◽  
Human Herpes Virus ◽  
Herpès Virus ◽  
Nasal Carcinoma

Human herpes virus 8 (Kaposi’s sarcoma herpesvirus)

Oral Oncology ◽  
1998 ◽  
Vol 34 (1) ◽  
pp. 5-14 ◽  
Author(s):  
S.R Porter ◽  
L Di Alberti ◽  
N Kumar
Keyword(s):  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Human Herpes ◽  
Human Herpes Virus 8 ◽  
Human Herpes Virus ◽  
Herpès Virus

Targeting the PI3K and MAPK pathways to treat Kaposi’s sarcoma-associated herpes virus infection and pathogenesis

2007 ◽  
Vol 11 (5) ◽  
pp. 589-599 ◽  
Author(s):  
Phelps J Lambert ◽  
Aniqa Z Shahrier ◽  
Audy G Whitman ◽  
Ossie F Dyson ◽  
Adrian J Reber ◽  
...  
Keyword(s):  
Virus Infection ◽  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Herpes Virus Infection ◽  
Mapk Pathways ◽  
Herpès Virus

Association of human herpes virus with pulmonary Kaposi's sarcoma

The Lancet ◽  
1995 ◽  
Vol 346 (8976) ◽  
pp. 712 ◽  
Author(s):  
Mark Howard ◽  
Nicola Brink ◽  
Robert Miller ◽  
Richard Tedder
Keyword(s):  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Human Herpes ◽  
Human Herpes Virus ◽  
Herpès Virus

scholarly journals Kaposi's Sarcoma Associated-Herpes Virus (KSHV) Seroprevalence in Pregnant Women in South Africa

2010 ◽  
Vol 5 (1) ◽  
pp. 14 ◽  
Author(s):  
Babatyi I Malope-Kgokong ◽  
Patrick MacPhail ◽  
Georgina Mbisa ◽  
Edith Ratshikhopa ◽  
Mhairi Maskew ◽  
...  
Keyword(s):  
South Africa ◽  
Pregnant Women ◽  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Herpès Virus

Kaposi's sarcoma-associated herpes virus complement control protein: KCP – complement inhibition and more

2007 ◽  
Vol 44 (1-3) ◽  
pp. 11-22 ◽  
Author(s):  
Linda Mark ◽  
O. Brad Spiller ◽  
Bruno O. Villoutreix ◽  
Anna M. Blom
Keyword(s):  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Complement Inhibition ◽  
Complement Control Protein ◽  
Herpès Virus ◽  
Control Protein

scholarly journals Impaired CTL Recognition of Cells Latently Infected with Kaposi’s Sarcoma-Associated Herpes Virus

2000 ◽  
Vol 165 (4) ◽  
pp. 2077-2083 ◽  
Author(s):  
Christian Brander ◽  
Todd Suscovich ◽  
Yun Lee ◽  
Phuong Thi Nguyen ◽  
Paula O’Connor ◽  
...  
Keyword(s):  
Kaposi's Sarcoma ◽  
Herpes Virus ◽  
Kaposi’S Sarcoma ◽  
Latently Infected ◽  
Herpès Virus
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