scholarly journals Bone marrow transplantation for transfused patients with severe aplastic anemia using cyclophosphamide and total lymphoid irradiation as conditioning therapy: long-term follow-up from a single center

1999 ◽  
Vol 24 (3) ◽  
pp. 253-257 ◽  
Author(s):  
D Gaziev ◽  
C Giardini ◽  
M Galimberti ◽  
G Lucarelli ◽  
E Angelucci ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Aplastic Anemia ◽  
Marrow Transplantation ◽  
Single Center ◽  
Total Lymphoid Irradiation ◽  
Long Term Follow Up ◽  
Conditioning Therapy

scholarly journals Increased incidence of solid malignant tumors after bone marrow transplantation for severe aplastic anemia [see comments]

Blood ◽  
1991 ◽  
Vol 78 (2) ◽  
pp. 277-279 ◽  
Author(s):  
G Socie ◽  
M Henry-Amar ◽  
JM Cosset ◽  
A Devergie ◽  
T Girinsky ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Aplastic Anemia ◽  
Marrow Transplantation ◽  
Malignant Tumors ◽  
Conditioning Regimen ◽  
Severe Aplastic Anemia ◽  
Male Patients

Abstract From May 1980 to December 1989, 107 consecutive patients with non- constitutional severe aplastic anemia underwent bone marrow transplantation at our institution using cyclophosphamide and thoraco- abdominal irradiation as conditioning regimen. During the same period, 40 patients with Fanconi anemia were also grafted after a similar conditioning, giving a total series of 147 patients. With a mean follow- up of 64 months, four male patients developed a solid malignant tumor, a number that leads to an 8-year cumulative incidence rate of 22% (eg, relative risk to general population = 41, P less than .001). These results should be considered as a warning to clinicians who follow these successfully grafted long-term patients.

scholarly journals Long-Term Follow-Up of Thyroid Function in Patients Who Received Bone Marrow Transplantation during Childhood and Adolescence

2004 ◽  
Vol 89 (12) ◽  
pp. 5981-5986 ◽  
Author(s):  
Hiroyuki Ishiguro ◽  
Yukiharu Yasuda ◽  
Yuuichiro Tomita ◽  
Tsuyoshi Shinagawa ◽  
Takashi Shimizu ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplantation ◽  
Thyroid Function ◽  
Marrow Transplantation ◽  
Childhood And Adolescence ◽  
Long Term Follow Up
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